Shu-Chieh Hu Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Researcher

National Center for Toxicological Research

faculty

7 h-index 11 pubs 255 cited

Research Areas

Carcinogens and Genotoxicity Assessment Pharmacological Effects and Toxicity Studies Metabolism and Genetic Disorders Animal Models in Toxicology Research Health and Medical Research Impacts

Links

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OverviewAI-generated summary

Shu-Chieh Hu's research focuses on the toxicokinetics and genotoxicity of chemical compounds, particularly in the context of inhalation exposure. Her recent publications investigate the absorption, distribution, metabolism, and excretion of NNK, a known carcinogen, in Sprague-Dawley rats via nose-only inhalation, intraperitoneal injection, and oral gavage. Hu also studies the pharmacokinetics of nicotine and its metabolites under similar exposure routes. Her work includes detailed toxicity assessments, such as 14-day and 90-day nose-only inhalation toxicity studies, and examines the dose-response relationship using principles like Haber's Rule. Hu has a h-index of 7 with 11 total publications and 255 citations. She frequently collaborates with researchers at the National Center for Toxicological Research, including Matthew Bryant, Sherry M. Lewis, Hyun-Ki Kang, and Paul C. Howard, with whom she shares multiple publications.

Metrics

  • h-index: 7
  • Publications: 11
  • Citations: 255

Selected Publications

  • Pharmacokinetic analysis of nicotine and its metabolites (cotinine and <i>trans</i>-3′-hydroxycotinine) in male Sprague-Dawley rats following nose-only inhalation, oral gavage, and intravenous infusion of nicotine (2024) DOI
  • 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats (2021) DOI
  • 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats (2021) DOI
  • Toxicokinetic and Genotoxicity Study of NNK in Male Sprague Dawley Rats Following Nose-Only Inhalation Exposure, Intraperitoneal Injection, and Oral Gavage (2021) DOI

Collaborators

Researchers in the database who share publications

Matthew Bryant National Center for Toxicological Research 4 shared publications Sherry M. Lewis National Center for Toxicological Research 4 shared publications Hyun-Ki Kang National Center for Toxicological Research 4 shared publications Paul C. Howard National Center for Toxicological Research 4 shared publications Seonggi Min National Center for Toxicological Research 3 shared publications Dong-Jin Yang National Center for Toxicological Research 3 shared publications Raúl Trbojevich National Center for Toxicological Research 3 shared publications Mason G. Pearce National Center for Toxicological Research 3 shared publications

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