Shu-Chieh Hu

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Researcher

NCTR

Also affiliated: IIT Research Institute (2009–2015); United States Food and Drug Administration (2018–2024); Illinois Institute of Technology (2012)

Faculty Researcher

8 h-index 11 pubs 267 cited

Research Areas

Biomedical Subjects

Links

Lab Website

OverviewAI-generated summary

Shu-Chieh Hu conducts research focused on toxicology, with a particular emphasis on inhalation exposure and the study of nitrosamines. Recent publications investigate the toxicokinetic and genotoxicity of NNK (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone) in Sprague Dawley rats, examining different exposure routes including nose-only inhalation, intraperitoneal injection, and oral gavage. Further studies have explored the pharmacokinetics of nicotine and its metabolites in rats following various administration methods, and assessed the 14-day and 90-day nose-only inhalation toxicity of NNK in Sprague Dawley rats. Hu's work also includes analysis of Haber's Rule in relation to NNK inhalation toxicity. Hu has published 11 papers with 260 citations and an h-index of 8. Key collaborators include Matthew Bryant, Sherry M. Lewis, Hyun-Ki Kang, and Paul C. Howard, all from the National Center for Toxicological Research, with whom Hu has co-authored four publications each.

Metrics

h-index: 8
Publications: 11
Citations: 267

Selected Publications

Pharmacokinetic analysis of nicotine and its metabolites (cotinine and <i>trans</i>-3′-hydroxycotinine) in male Sprague-Dawley rats following nose-only inhalation, oral gavage, and intravenous infusion of nicotine (2024)

Toxicological Sciences 8 citations DOI OpenAlex
90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats (2021)

Food and Chemical Toxicology 6 citations DOI OpenAlex
14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats (2021)

Toxicological Sciences 7 citations DOI OpenAlex
Toxicokinetic and Genotoxicity Study of NNK in Male Sprague Dawley Rats Following Nose-Only Inhalation Exposure, Intraperitoneal Injection, and Oral Gavage (2021)

Toxicological Sciences 15 citations DOI OpenAlex
Evaluation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) mutagenicity using in vitro and in vivo Pig-a assays (2018)

Mutation Research/Genetic Toxicology and Environmental Mutagenesis 11 citations DOI OpenAlex