Camila Simões
Assistant Professor
University of Arkansas for Medical Sciences
faculty
Pathology, College of Medicine
Research Areas
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Biography and Research Information
OverviewAI-generated summary
Camila Simões is an Assistant Professor in the Department of Pathology at the University of Arkansas for Medical Sciences. Her research focuses on developing novel therapeutic strategies for various cancers, particularly liver and pancreatic cancers. She investigates the potential of oncolytic viruses, such as Morreton virus and Jurona virus, as platforms for cancer virotherapy, often in combination with immune checkpoint blockade.
Dr. Simões' work also explores dietary interventions, such as methionine restriction, to enhance the response to immune checkpoint inhibitors in colorectal cancer models. Additionally, her research includes repurposing existing vaccines, like the MMR vaccine, for cancer immunotherapy. Her scholarly output includes work on the histopathology of liver diseases and the validation of diagnostic markers, such as metallothionein immunohistochemistry for Wilson Disease. She has published 50 papers, with an h-index of 7 and 128 total citations. Key collaborators include Steven R. Post, Martin J. Cannon, Alexei G. Basnakian, and Mulu Z. Tesfay.
Metrics
- h-index: 7
- Publications: 50
- Citations: 128
Selected Publications
- Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models (2025) DOI
- Pancreatic tumor microenvironment reprogramming via alloantigen-expressing virotherapy elicits tumor rejection and improves immunotherapy response (2025) DOI
- Abstract 945: Live attenuated MMR vaccines modulate tumor immune cell infiltration and synergize with standard of care to prolong survival in preclinical HCC models (2025) DOI
- Enhancing immune response and survival in hepatocellular carcinoma with novel oncolytic Jurona virus and immune checkpoint blockade (2024) DOI
- S5193 More Than Just a Variceal Bleed: Multiple Portal Hypertensive Gastric Polyps in a Case of Advanced Cirrhosis (2024) DOI
- Validation of Metallothionein Immunohistochemistry as a Highly Sensitive Screening Test for Wilson Disease (2024) DOI
- Enhancing Neoadjuvant Virotherapy’s Effectiveness by Targeting Stroma to Improve Resectability in Pancreatic Cancer (2024) DOI
- Abstract 588: Preclinical evaluation of novel chimeric vesiculovirus mediated expression of proteolytic enzymes targeting two major stromal components of pancreatic ductal adenocarcinoma (2024) DOI
- Abstract 5004: Oncolytic Jurona-driven systemic and intratumoral immunotherapy combined with immune checkpoint blockade boost immune response and survival in hepatocellular carcinoma models (2024) DOI
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model (2023) DOI
- S3266 A Comparison of Two Cases of Acute Graft versus Host Disease Following Liver Transplant (2022) DOI
- Repurposing live attenuated trivalent MMR vaccine as cost-effective cancer immunotherapy (2022) DOI
- Characterization of Morreton virus as an oncolytic virotherapy platform for liver cancers (2022) DOI
- Characterization of Morreton Virus (MORV) as a Novel Oncolytic Virotherapy Platform for Liver Cancers (2022) DOI
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