Stefanie Kennon‐McGill

Researcher

UAMS

Last publication 2026 Last refreshed 2026-05-16

faculty

12 h-index 32 pubs 826 cited

Research Areas

Links

ORCID Research Group

OverviewAI-generated summary

Stefanie Kennon‐McGill investigates the mechanisms underlying drug-induced liver injury, with a focus on acetaminophen. Her work has explored the role of metabolic pathways, such as pyruvate and alanine metabolism, in maintaining antioxidant capacity and resistance to oxidative stress during liver injury. Kennon‐McGill has also examined the potential of exogenous compounds, like phosphatidic acid, to mitigate acetaminophen-induced liver damage. Her research extends to the use of advanced models, including a human quad liver-on-chip system, to bridge the gap between animal studies and human responses in toxicology and pharmacology, particularly concerning cannabis extracts. Additionally, her work has addressed perceptions and use of marijuana and cannabidiol among pregnant individuals. Kennon‐McGill has collaborated with researchers from the University of Arkansas for Medical Sciences and the University of Arkansas at Fayetteville.

Metrics

h-index: 12
Publications: 32
Citations: 826

Selected Publications

NAPQI is absent in the mouse brain after sub-hepatotoxic and hepatotoxic doses of acetaminophen (2025)

3 citations DOI OpenAlex
Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract (2024)

3 citations DOI OpenAlex
Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult (2023)

25 citations DOI OpenAlex
Factors associated with ever using cannabidiol in a cohort of younger pregnant people (2023)

10 citations DOI OpenAlex
Proteomics Indicates Lactate Dehydrogenase Is Prognostic in Acetaminophen-Induced Acute Liver Failure Patients and Reveals Altered Signaling Pathways (2022)

36 citations DOI OpenAlex
Proteomics Indicates Lactate Dehydrogenase is Prognostic in Acetaminophen-induced Acute Liver Failure Patients and Reveals a Role for LKB1-AMPK Signaling (2021)

DOI OpenAlex
Short‐Term Safety of Repeated Acetaminophen Use in Patients With Compensated Cirrhosis (2021)

22 citations DOI OpenAlex
Exogenous phosphatidic acid reduces acetaminophen-induced liver injury in mice by activating hepatic interleukin-6 signaling through inter-organ crosstalk (2021)

21 citations DOI OpenAlex
Ototoxicity and Drug Transport in the Cochlea (2021)

DOI OpenAlex
55715 Quantification of Neonatal THC Exposure Following Prenatal Marijuana Use (2021)

DOI OpenAlex