Jia‐Long Fang Source Confirmed

OverviewAI-generated summary

Jia-Long Fang's research investigates the toxicological and pharmacological effects of various chemical compounds and natural products. His work includes studies on the carcinogenicity of dyes such as gentian violet and malachite green, and the evaluation of polyethylene glycols' toxicity in Sprague Dawley rats. Fang also explores the mechanisms underlying metabolic disorders, specifically focusing on the thromboxane A2/thromboxane A2 receptor axis in non-alcoholic fatty liver disease. His recent publications demonstrate the amelioration of metabolic-associated fatty liver disease and glucolipid metabolism disorders through natural compounds like piperlongumine and ginkgolide B, which antagonize the thromboxane A2 receptor or inhibit its synthesis, respectively.

Further research by Fang examines the impact of microbial metabolites on physiological processes, such as the mitigation of oxidative stress-related intestinal aging by *Lactiplantibacillus plantarum* CCFM8610 through its metabolite indole-3-lactic acid. He has also contributed to understanding immune responses, including the evaluation of anti-PEG antibodies in relation to anaphylaxis after mRNA COVID-19 vaccination. His work also touches upon the biochemical pathways of drug metabolism, as seen in his study on the oxidation of 7-hydroxycannabidiol by NAD(P)+-dependent alcohol oxidoreductases.

Fang's scholarship metrics include an h-index of 29 and over 2,900 citations across 62 publications. He has collaborated with several researchers at the National Center for Toxicological Research, including Frederick A. Beland, Mackean P. Maisha, Michelle M. Vanlandingham, and Robert P. Felton.

Metrics

• h-index: 29
• Publications: 62
• Citations: 2,929