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Presence Current · Arkansas
Last published 2021
Sources OpenAlex · ORCID
Refreshed 2026-10-07

Thomas R. Groves

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Also affiliated: University of Arkansas Medical Center (2018); Veterans Health Administration (2018); Shriners Hospitals for Children - Philadelphia (2020); Temple University (2020)

14 h-index 18 pubs 542 cited

  • Animals
  • Mice, Inbred C57BL
  • Mice
  • Hippocampus
  • Male
  • Dendrites
  • Dendritic Spines
  • Cognition
  • Female
  • Aging
  • Fluorouracil
  • Neurons
  • Behavior, Animal
  • Spatial Memory
  • Gene Expression Regulation

Biography and Research Information

OverviewAI-generated summary

Thomas R. Groves investigates the neurological and cognitive effects of various medical treatments and environmental exposures in murine models. His research has examined the impact of chemotherapy agents, such as 5-fluorouracil and methotrexate, as well as charged particle radiation, on neuronal morphology, dendritic complexity, and cognitive function, particularly in aged mice and across sexes. Groves also studies the role of glial cells in axon regeneration and functional recovery within the central nervous system. His work has explored how Alzheimer's amyloid-beta peptide affects glucose transporter localization in astrocytes, with implications for brain and blood glucose levels. Groves's research is supported by his publication record, including studies on the late effects of radiation on social and cognitive behavior, and has resulted in 19 publications with an h-index of 14 and 538 citations.

Metrics

  • h-index: 14
  • Publications: 18
  • Citations: 542

Selected Publications

  • The Effects of 5-Fluorouracil/Leucovorin Chemotherapy on Cognitive Function in Male Mice (2021)
    Frontiers in Molecular Biosciences 16 citations DOI OpenAlex
  • Late Effects of 1H + 16O on Short-Term and Object Memory, Hippocampal Dendritic Morphology and Mutagenesis (2020)
    Frontiers in Behavioral Neuroscience 22 citations DOI OpenAlex
  • Early Effects of Cyclophosphamide, Methotrexate, and 5-Fluorouracil on Neuronal Morphology and Hippocampal-Dependent Behavior in a Murine Model (2019)
    Toxicological Sciences 24 citations DOI OpenAlex
  • Loss of C/EBPδ Exacerbates Radiation-Induced Cognitive Decline in Aged Mice due to Impaired Oxidative Stress Response (2019)
    International Journal of Molecular Sciences 15 citations DOI OpenAlex
  • Late Effects of 16O-Particle Radiation on Female Social and Cognitive Behavior and Hippocampal Physiology (2019)
    Radiation Research 34 citations DOI OpenAlex
  • Effects of thioTEPA chemotherapy on cognition and motor coordination (2018)
    Synapse 10 citations DOI OpenAlex
  • Behavioral Effects of Focal Irradiation in a Juvenile Murine Model (2018)
    Radiation Research 13 citations DOI OpenAlex
  • Early effects of 16O radiation on neuronal morphology and cognition in a murine model (2018)
    Life Sciences in Space Research 37 citations DOI OpenAlex
  • Late effects of 1H irradiation on hippocampal physiology (2018)
    Life Sciences in Space Research 20 citations DOI OpenAlex
  • Assessment of Hippocampal Dendritic Complexity in Aged Mice Using the Golgi-Cox Method (2017)
    Journal of Visualized Experiments 6 citations DOI OpenAlex
  • Changes in cognition and dendritic complexity following intrathecal methotrexate and cytarabine treatment in a juvenile murine model (2017)
    Behavioural Brain Research 30 citations DOI OpenAlex
  • Effects of1H +16O Charged Particle Irradiation on Short-Term Memory and Hippocampal Physiology in a Murine Model (2017)
    Radiation Research 31 citations DOI OpenAlex
  • Assessment of Hippocampal Dendritic Complexity in Aged Mice Using the Golgi-Cox Method (2017)
    Journal of Visualized Experiments 18 citations DOI OpenAlex
  • 5-Fluorouracil chemotherapy upregulates cytokines and alters hippocampal dendritic complexity in aged mice (2016)
    Behavioural Brain Research 75 citations DOI OpenAlex

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Collaboration Network

33 Collaborators 4 Institutions 1 Country

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