A
Ambika Verma
Assistant Staff Scientist
staff
Geriatrics, College of Medicine
13 h-index
61 pubs
528 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Ambika Verma's research investigates the molecular mechanisms underlying neuroinflammation and mitochondrial dysfunction, with a particular focus on the role of oxidative stress. Her work has explored how bacterial components, such as lipopolysaccharides from P. gingivalis, can induce these detrimental processes in neuronal and microglial cells. Verma has also examined the impact of specific nutrients, like valine, and pharmacological compounds on mitochondrial function and cellular protection against oxidative damage. Her publications include studies on the effects of amino acid-based dietary supplements on older adults and the mechanisms of bacterial effector suppression of host cellular responses. Verma has a publication record of 55 papers, with 492 citations and an h-index of 13. She collaborates with researchers at the University of Arkansas for Medical Sciences, including Pankaj Patyal, Gohar M. Azhar, Jeanne Y. Wei, and Robert R. Wolfe.
Metrics
- h-index: 13
- Publications: 61
- Citations: 528
Selected Publications
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Biology of Aging I Antisense Oligonucleotide-Mediated SRF Reduction Ameliorates Mitochondrial Dysfunction in Cardiac Aging (2025)
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P. gingivalis-LPS Activates the Alzheimer’s Disease-Associated Amyloid Secretase Pathway via Caspase-4 (2025)
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Mitochondrial Dynamics in Aging Heart (2025)
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Differential microRNA profiling of the Marshallese population in Arkansas reveals a higher association with chronic diseases (2025)
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Porphyromonas gingivalis-Lipopolysaccharide Induced Caspase-4 Dependent Noncanonical Inflammasome Activation Drives Alzheimer’s Disease Pathologies (2025)
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Cardiac-specific overexpression of serum response factor regulates age-associated decline in mitochondrial function (2025)
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CARDIAC SPECIFIC OVEREXPRESSION OF SERUM RESPONSE FACTOR ALTERS MITOCHONDRIAL STRUCTURE AND FUNCTION (2024)
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DIFFERENTIAL EFFECT OF SIRT1 ON MITOCHONDRIAL FUNCTION: INSIGHTS INTO MITOCHONDRIAL RESPIRATORY COMPLEXES (2024)
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DIFFERENTIAL MICRORNAS PROFILING OF MARSHALLESE IN ARKANSAS IS ASSOCIATED WITH CHRONIC DISEASES OF AGING (2024)
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P. GINGIVALIS-LPS PROMOTES AD/ADRD VIA CASPASE-4-MEDIATED NONCANONICAL INFLAMMASOME PATHWAY (2024)
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The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function (2024)
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Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells (2024)
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Deletion of Interleukin-1β Converting Enzyme Alters Mouse Cardiac Structure and Function (2024)
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Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome (2024)
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Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function (2024)
Collaboration Network
Top Collaborators
Pankaj Patyal
University of Arkansas for Medical Sciences
23 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
- Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function
Showing 5 of 23 shared publications
Jeanne Y. Wei
University of Arkansas for Medical Sciences
23 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
- Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function
Showing 5 of 23 shared publications
Gohar Azhar
Institute on Aging
21 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
- Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function
Showing 5 of 21 shared publications
Xiaomin Zhang
Institute on Aging (US)
16 shared publications
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
- Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function
Showing 5 of 16 shared publications
Shakshi Sharma
University of Arkansas for Medical Sciences
9 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
- DIFFERENTIAL EFFECT OF SIRT1 ON MITOCHONDRIAL FUNCTION: INSIGHTS INTO MITOCHONDRIAL RESPIRATORY COMPLEXES
Showing 5 of 9 shared publications
Changhoon Oh
6 shared publications
- Shigella OspC3 suppresses murine cytosolic LPS sensing
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
- <i>Shigella</i> OspC3 Suppresses Murine Cytosolic LPS Sensing
- Neutrophil Inflammasomes Sense the Subcellular Delivery Mechanism of Translocated Bacterial Effectors and Toxins
- Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
Showing 5 of 6 shared publications
Youssef Aachoui
6 shared publications
- Shigella OspC3 suppresses murine cytosolic LPS sensing
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
- <i>Shigella</i> OspC3 Suppresses Murine Cytosolic LPS Sensing
- Neutrophil Inflammasomes Sense the Subcellular Delivery Mechanism of Translocated Bacterial Effectors and Toxins
- Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
Showing 5 of 6 shared publications
Edward A. Miao
4 shared publications
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
- Neutrophil Inflammasomes Sense the Subcellular Delivery Mechanism of Translocated Bacterial Effectors and Toxins
- Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
Robert R. Wolfe
University of Arkansas for Medical Sciences
4 shared publications
In database
- Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
- Correction to: Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement versus whey protein in low physical functioning older adults
- EAAS AND WHEY PROTEIN MAY IMPROVE PHYSICAL FUNCTION OF OLDER ADULTS INDEPENDENTLY OF GUT MICROBIOME
Lupeng Li
3 shared publications
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
- Neutrophil Inflammasomes Sense the Subcellular Delivery Mechanism of Translocated Bacterial Effectors and Toxins
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
Arianna D. Reuven
3 shared publications
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
- Neutrophil Inflammasomes Sense the Subcellular Delivery Mechanism of Translocated Bacterial Effectors and Toxins
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
James B. Bliska
3 shared publications
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
- Neutrophil Inflammasomes Sense the Subcellular Delivery Mechanism of Translocated Bacterial Effectors and Toxins
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
Fathima S. Ameer
Institute on Aging (US)
3 shared publications
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- SIRTUIN 1 ISOFORMS DIFFERENTIALLY IMPACT MITOCHONDRIAL GENE EXPRESSION AND FUNCTION IN MUSCLE CELLS
Grishma KC
Institute on Aging (US)
3 shared publications
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
Yingni Che
University of Arkansas for Medical Sciences
3 shared publications
In database
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- SIRTUIN 1 ISOFORMS DIFFERENTIALLY IMPACT MITOCHONDRIAL GENE EXPRESSION AND FUNCTION IN MUSCLE CELLS
Similar Researchers
Based on overlapping research topics
Pankaj Patyal
University of Arkansas for Medical Sciences
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W. Sue T. Griffin
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University of Arkansas at Fayetteville
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