Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
R
Renny Shang-Lun Lan
Assistant Professor
Also affiliated: National Institutes of Health (2009); Georgetown University (2009–2012); University of Arkansas Medical Center (2024–2026); The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (2015–2016); National Institute of Diabetes and Digestive and Kidney Diseases (2009); Arkansas Children's Nutrition Center (2020–2026); Georgetown Lombardi Comprehensive Cancer Center (2009–2012); Arkansas Children's Research Institute (2021–2026); The Ohio State University (2015–2017)
14 h-index
62 pubs
1,005 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Renny Shang-Lun Lan's research focuses on the application of metabolomics and mass spectrometry to investigate biological processes and disease mechanisms. He has explored metabolic reprogramming in mantle cell lymphoma, examining how it influences oxidative phosphorylation and presents a potential therapeutic target. His work also includes the development and refinement of analytical techniques, such as a scoping review on current practices in LC-MS untargeted metabolomics, specifically regarding the use of pooled quality control samples. Lan has investigated the role of iron uptake regulated by transferrin receptor 1 in bone mass maintenance in mice, particularly its impact on osteoclast mitochondria and cytoskeleton. Additionally, his research has examined the effects of glutathione peroxidase-1 overexpression on oxidative stress and kidney pathology in aged mice, as well as metabolomic profiles in cigarette smokers and the associations between maternal obesity and offspring gut microbiome.
Metrics
- h-index: 14
- Publications: 62
- Citations: 1,005
Positions
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Assistant Professor 2020–presentUniversity of Arkansas for Medical Sciences Pediatrics ORCID
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Assistant Professor 2020–presentArkansas Children's Hospital Pediatrics ORCID
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Operations Director, Metabolomics and Analytical Chemistry Core 2020–presentArkansas Children's Nutrition Center Pediatrics ORCID
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Instructor 2016–2020University of Arkansas for Medical Sciences Biochemistry and Molecular Biology ORCID
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Research Graduate Associate 2012–2016Ohio State University Comprehensive Cancer Center ORCID
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Lab Manager/ Research Scientist 2007–2012Georgetown University Comprehensive Cancer Center ORCID
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Research/Teaching assistant 2003–2006North Carolina State University Microbiology ORCID
Selected Publications
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From known chemical space to unannotated metabolites: a cluster-guided retention-time driven framework for biologically informed annotation (2026)
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Lactiplantibacillus plantarum promotes intestinal goblet cell differentiation via indole-3-lactic acid–AHR signaling in pigs (2026)
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Metabolic phenotypes of doxorubicin-induced cardiotoxicity among patients with breast cancer (2026)
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Carnitine deficiency alters fuel metabolism and voluntary wheel running in mice (2026)
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Integrating fingerprint prediction and physicochemical property filtering to annotate unknown metabolites from high-resolution MS/MS spectra (2026)
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Metabolic Reprogramming Induced by Mitochondrial Citrate Carrier Deletion Mitigates Antibiotics-Induced Acute Tubular Injury (2026)
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Carnitine deficiency alters fuel metabolism and voluntary wheel running in mice (2026)
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Improvement of glucose homeostasis during leptin treatment does not alter the intestinal microbiome in male diabetic UC Davis type-2 diabetes mellitus rats (2026)
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Circulating short- and medium-chain fatty acids in pregnancy and associations with maternal and infant metabolism, inflammation, and body composition (2026)
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Xenometabolomics reveals metabolic functional guilds unique to specific inulin subtypes in human gut microbiota cultures (2025)
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Prenatal Exercise Training Alters Plasma Metabolite Responses To Acute Exercise In Pregnant Women With Obesity (2025)
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Associations Between Serum Gut-Derived Tryptophan Metabolites and Cardiovascular Health Markers in Adolescents with Obesity (2025)
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Beyond the Known Metabolome: Predictive Strategies for Dark Matter Discovery (2025)
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A narrative review of metabolomics approaches in identifying biomarkers of doxorubicin-induced cardiotoxicity (2025)
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Evaluation of ion source parameters and liquid chromatography methods for plasma untargeted metabolomics using orbitrap mass spectrometer (2025)
Collaboration Network
Top Collaborators
Lindsay Pack
Arkansas Children's Nutrition Center
13 shared publications
In database
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- Infant intakes of human milk branched chain amino acids are negatively associated with infant growth and influenced by maternal body mass index
- Elamipretide treatment during pregnancy ameliorates the progression of polycystic kidney disease in maternal and neonatal mice with PKD1 mutations
- Net release and uptake of xenometabolites across intestinal, hepatic, muscle, and renal tissue beds in healthy conscious pigs
Showing 5 of 13 shared publications
Brian D. Piccolo
Arkansas Children's Nutrition Center
11 shared publications
In database
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Exercise training modifies xenometabolites in gut and circulation of lean and obese adults
- Net release and uptake of xenometabolites across intestinal, hepatic, muscle, and renal tissue beds in healthy conscious pigs
- Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues
- Colonic epithelial hypoxia remains constant during the progression of diabetes in male UC Davis type 2 diabetes mellitus rats
Showing 5 of 11 shared publications
Samuel G. Mackintosh
University of Arkansas for Medical Sciences
7 shared publications
In database
- Metabolic reprogramming toward oxidative phosphorylation identifies a therapeutic target for mantle cell lymphoma
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data
- Local and Relayed Effects of Deep Brain Stimulation of the Pedunculopontine Nucleus
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
Showing 5 of 7 shared publications
Elisabet Børsheim
Arkansas Children's Nutrition Center
7 shared publications
In database
- Infant intakes of human milk branched chain amino acids are negatively associated with infant growth and influenced by maternal body mass index
- Associations Between Serum Gut-Derived Tryptophan Metabolites and Cardiovascular Health Markers in Adolescents with Obesity
- Circulating long-chain acylcarnitine concentrations are not affected by exercise training in pregnant women with obesity
- Prenatal Exercise Training Alters Plasma Metabolite Responses To Acute Exercise In Pregnant Women With Obesity
- Carnitine deficiency alters fuel metabolism and voluntary wheel running in mice
Showing 5 of 7 shared publications
Hailemariam Abrha Assress
University of Arkansas for Medical Sciences
6 shared publications
In database
- Optimization of Mass Spectrometric Parameters in Data Dependent Acquisition for Untargeted Metabolomics on the Basis of Putative Assignments
- Evaluation of ion source parameters and liquid chromatography methods for plasma untargeted metabolomics using orbitrap mass spectrometer
- Prenatal Exercise Training Alters Plasma Metabolite Responses To Acute Exercise In Pregnant Women With Obesity
- Ion Source Optimization and Lc Separation Method Development for Comprehensive Untargeted Metabolomics Using Orbitrap Mass Spectrometer
- Evaluation of Ion Source Parameters and Liquid Chromatography Methods for Plasma Untargeted Metabolomics Using Orbitrap Mass Spectrometer
Showing 5 of 6 shared publications
Mário G. Ferruzzi
Arkansas Children's Hospital
6 shared publications
In database
- Optimization of Mass Spectrometric Parameters in Data Dependent Acquisition for Untargeted Metabolomics on the Basis of Putative Assignments
- Evaluation of ion source parameters and liquid chromatography methods for plasma untargeted metabolomics using orbitrap mass spectrometer
- Associations Between Serum Gut-Derived Tryptophan Metabolites and Cardiovascular Health Markers in Adolescents with Obesity
- Ion Source Optimization and Lc Separation Method Development for Comprehensive Untargeted Metabolomics Using Orbitrap Mass Spectrometer
- The Gut Microbiome Across the Murine Lifespan: Impact of Diet and Its Association With Inflammation, Lipids, Liver Cancer, and Lifespan
Showing 5 of 6 shared publications
Sean H. Adams
University of California, Davis
5 shared publications
In database
- Exercise training modifies xenometabolites in gut and circulation of lean and obese adults
- Net release and uptake of xenometabolites across intestinal, hepatic, muscle, and renal tissue beds in healthy conscious pigs
- Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues
- Xenometabolomics reveals metabolic functional guilds unique to specific inulin subtypes in human gut microbiota cultures
- Prenatal Exercise Training Alters Plasma Metabolite Responses To Acute Exercise In Pregnant Women With Obesity
Aline Andres
Arkansas Children's Nutrition Center
5 shared publications
In database
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Infant intakes of human milk branched chain amino acids are negatively associated with infant growth and influenced by maternal body mass index
- Circulating long-chain acylcarnitine concentrations are not affected by exercise training in pregnant women with obesity
- Circulating short- and medium-chain fatty acids in pregnancy and associations with maternal and infant metabolism, inflammation, and body composition
- Prenatal Exercise Training Alters Plasma Metabolite Responses To Acute Exercise In Pregnant Women With Obesity
Sree V. Chintapalli
Arkansas Children's Nutrition Center
4 shared publications
In database
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Gut Microbiome and Metabolome Modulation by Maternal High-Fat Diet and Thermogenic Challenge
- Beyond the Known Metabolome: Predictive Strategies for Dark Matter Discovery
- From known chemical space to unannotated metabolites: a cluster-guided retention-time driven framework for biologically informed annotation
Laxmi Yeruva
Arkansas Children's Nutrition Center
4 shared publications
In database
- Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues
- Colonic epithelial hypoxia remains constant during the progression of diabetes in male UC Davis type 2 diabetes mellitus rats
- Associations between maternal microbiome, metabolome and incidence of low-birth weight in Guatemalan participants from the Women First Trial
- Improvement of glucose homeostasis during leptin treatment does not alter the intestinal microbiome in male diabetic UC Davis type-2 diabetes mellitus rats
Alan J. Tackett
Arkansas Children's Hospital
3 shared publications
In database
- ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data
- Local and Relayed Effects of Deep Brain Stimulation of the Pedunculopontine Nucleus
- Phosphoproteomics Provides Novel Insights into the Response of Primary Acute Lymphoblastic Leukemia Cells to Microtubule Depolymerization in G1 Phase of the Cell Cycle
Dao‐Fu Dai
Johns Hopkins University (US)
3 shared publications
- Glutathione peroxidase‐1 overexpression reduces oxidative stress, and improves pathology and proteome remodeling in the kidneys of old mice
- Elamipretide treatment during pregnancy ameliorates the progression of polycystic kidney disease in maternal and neonatal mice with PKD1 mutations
- Metabolic Reprogramming Induced by Mitochondrial Citrate Carrier Deletion Mitigates Antibiotics-Induced Acute Tubular Injury
Bhaba Krishna Das
Southern California Institute for Research and Education (US)
3 shared publications
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
Toshifumi Fujiwara
Kyushu University Hospital (JP)
3 shared publications
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
Nükhet Aykin‐Burns
University of Arkansas for Medical Sciences
3 shared publications
In database
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
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