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Presence Current · Arkansas
Last published 2024
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Emory G. Malone

Graduate Research Assistant

Graduate Student Researcher

3 h-index 7 pubs 34 cited

  • DNA Helicases
  • Saccharomyces cerevisiae Proteins
  • G-Quadruplexes
  • DNA, Single-Stranded
  • Saccharomyces cerevisiae
  • DNA
  • DNA Replication
  • Viral Proteins
  • Bacteriophage T4
  • Humans
  • Models, Molecular
  • Protein Binding
  • Crystallography, X-Ray
  • Genomic Instability
  • Bacterial Proteins

Biography and Research Information

OverviewAI-generated summary

Emory G. Malone's research focuses on the molecular mechanisms of DNA processing and genome stability, with a particular emphasis on helicase function and DNA replication. Malone has investigated the role and regulation of Pif1 family helicases at the replication fork and their ability to unwind G-quadruplex and double-stranded DNA. Research also includes examining structural features of helicases, such as the Dda helicase, that influence their interaction with DNA-bound molecules. Additionally, Malone has explored aspects of genome editing, including distance-dependent effects of CRISPR/Cas9 in *Schizosaccharomyces pombe* and the genetic basis of specific alleles in this organism. The work also touches upon yeast genetics, investigating factors that affect spore and cell plating efficiency and the activation of meiotic recombination hotspots.

Metrics

  • h-index: 3
  • Publications: 7
  • Citations: 34

Selected Publications

  • Abstract 3871 Transcription factor Toe2 activates the meiotic recombination hotspot 4156 (2026)
    Journal of Biological Chemistry DOI OpenAlex
  • Agar lot-specific inhibition in the plating efficiency of yeast spores and cells (2024)
    G3 Genes Genomes Genetics 1 citation DOI OpenAlex
  • Distance-dependent effects on CRISPR/Cas9-mediated genome editing in Schizosaccharomyces pombe compromise efficiency and create unsought alleles (2024)
    PubMed 2 citations DOI OpenAlex
  • Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge (2024)
    Nature Communications 9 citations DOI OpenAlex
  • DNA sequences and distinct mechanisms for ura4-595 and ura4-294 alleles of S. pombe (2024)
    PubMed DOI OpenAlex
  • Role and Regulation of Pif1 Family Helicases at the Replication Fork (2022)
    International Journal of Molecular Sciences 14 citations DOI OpenAlex
  • Monitoring helicase-catalyzed unwinding of multiple duplexes simultaneously (2022)
    Methods in enzymology on CD-ROM/Methods in enzymology DOI OpenAlex
  • A structural feature of Dda helicase which enhances displacement of streptavidin and <i>trp</i> repressor from <scp>DNA</scp> (2021)
    Protein Science 8 citations DOI OpenAlex

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Collaboration Network

22 Collaborators 8 Institutions 3 Countries

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