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Biography and Research Information
OverviewAI-generated summary
Bertha Osei's research focuses on neuronal structure and function, with a particular emphasis on mitochondrial morphology in neurons. Her work investigates how mitochondrial dynamics, specifically fusion and fission processes, are regulated in an activity-dependent manner within dendritic compartments of CA1 pyramidal neurons. Osei has also explored the impact of experimental conditions, such as fixative type and oxygen levels during perfusion, on the preservation of neuronal mitochondrial morphology. Her research extends to molecular mechanisms, including the function of eukaryotic Pif1 helicase in unwinding DNA structures and the cellular impact of specific genetic variations in the HELB gene. Additionally, she has investigated the effects of pathogen-associated molecular patterns on gene transcription in immune cells.
Metrics
- h-index: 7
- Publications: 26
- Citations: 198
Selected Publications
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Rare SNP in the <i>HELB</i> gene interferes with RPA interaction and cellular function of HELB (2025)
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Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge (2024)
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Rare SNP in the <i>HELB</i> gene interferes with RPA interaction and cellular function of HELB (2024)
Collaboration Network
Top Collaborators
Tommy L. Lewis
Oklahoma Medical Research Foundation (US)
4 shared publications
- Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo
- Neuronal mitochondrial morphology is significantly affected by both fixative and oxygen level during perfusion
- Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons
- Neuronal mitochondrial morphology is significantly affected by both fixative and oxygen level during perfusion
Alicia K. Byrd
University of Arkansas for Medical Sciences
3 shared publications
In database
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
- Rare SNP in the <i>HELB</i> gene interferes with RPA interaction and cellular function of HELB
- Rare SNP in the <i>HELB</i> gene interferes with RPA interaction and cellular function of HELB
Su Yeon Kim
Korea Institute of Science and Technology (KR)
2 shared publications
- Neuronal mitochondrial morphology is significantly affected by both fixative and oxygen level during perfusion
- Neuronal mitochondrial morphology is significantly affected by both fixative and oxygen level during perfusion
Klaudia Strucinska
Oklahoma Medical Research Foundation (US)
2 shared publications
- Neuronal mitochondrial morphology is significantly affected by both fixative and oxygen level during perfusion
- Neuronal mitochondrial morphology is significantly affected by both fixative and oxygen level during perfusion
Kihoon Han
Korea University (KR)
2 shared publications
- Neuronal mitochondrial morphology is significantly affected by both fixative and oxygen level during perfusion
- Neuronal mitochondrial morphology is significantly affected by both fixative and oxygen level during perfusion
Seok‐Kyu Kwon
Korea Institute of Brain Science (KR)
2 shared publications
- Neuronal mitochondrial morphology is significantly affected by both fixative and oxygen level during perfusion
- Neuronal mitochondrial morphology is significantly affected by both fixative and oxygen level during perfusion
Daniel M. Virga
Columbia University (US)
2 shared publications
- Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo
- Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons
Stevie Hamilton
Columbia University (US)
2 shared publications
- Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo
- Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons
Abigail Morgan
Oklahoma Medical Research Foundation (US)
2 shared publications
- Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo
- Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons
Emiliano Zamponi
Columbia University (US)
2 shared publications
- Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo
- Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons
Victoria L. Hewitt
Columbia University (US)
2 shared publications
- Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo
- Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons
David Zhang
Columbia University (US)
2 shared publications
- Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo
- Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons
Kevin C. Gonzalez
Columbia University (US)
2 shared publications
- Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo
- Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons
Erik B. Bloss
Jackson Laboratory (US)
2 shared publications
- Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo
- Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons
Franck Polleux
Columbia University (US)
2 shared publications
- Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo
- Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons
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