Jerry Ware

High Impact

Professor

University of Arkansas for Medical Sciences

faculty

Physiology & Cell Biology, College of Medicine

60 h-index 220 pubs 13,272 cited

Research Areas

Platelet Disorders and Treatments Immune Response and Inflammation Health disparities and outcomes Cancer-related molecular mechanisms research Liver Disease Diagnosis and Treatment Cardiovascular Function and Risk Factors Chronic Obstructive Pulmonary Disease (COPD) Research Dialysis and Renal Disease Management

Links

ORCID Google Scholar Lab Website Research Group UAMS TRI Profile

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OverviewAI-generated summary

Jerry Ware, Professor in the Department of Physiology & Cell Biology at the University of Arkansas for Medical Sciences, investigates the multifaceted roles of platelets in various disease states. His research group focuses on understanding how platelets contribute to inflammation and disease progression, particularly in chronic kidney disease (CKD). Recent publications examine the inflammatory dysregulation driven by platelets in patients with advanced CKD and compare the efficacy of antiplatelet agents like ticagrelor and clopidogrel in mitigating this inflammation. His work also extends to the involvement of platelet glycoproteins, such as GPVI and GPIbα, in conditions like systemic sclerosis and non-alcoholic steatohepatitis (NASH), exploring their potential as therapeutic targets.

Ware's scholarship is characterized by a significant publication record, with 220 total publications and over 13,000 citations, reflected in his h-index of 60. He has received federal funding, including a $693,302 award from the NIH to study the role of platelets in radiation-induced immune dysregulation. His research network includes collaborations with several colleagues at the University of Arkansas for Medical Sciences, such as Nishank Jain and Adam Corken, with whom he has co-authored multiple publications. Ware leads an active research group and maintains a lab website, indicating ongoing research activities.

Metrics

h-index: 60
Publications: 220
Citations: 13,272

Selected Publications

Identification and Characterization of Platelet Surface-membrane-derived Microparticles before and after Total-body Irradiation (2025) DOI
Contrasting Effects of Platelet GPVI Deletion Versus Syk Inhibition on Mouse Jugular Vein Puncture Wound Structure (2025) DOI
A GPVI-platelet-neutrophil-NET axis drives systemic sclerosis (2025) DOI
OC 10.3 Platelets Mediate Intracranial Aneurysm Formation and Rupture in Mice (2023) DOI
Platelet Count and Platelet Volume in Patients with CKD (2023) DOI
438 Platelets, Inflammation and Thrombosis in Chronic Kidney Disease (2023) DOI
Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease (2023) DOI
Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study (2022) DOI
Murine models of glycoprotein Ib-IX (2022) DOI
Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer (2022) DOI
Platelet glycoprotein Ibα provides radiation protection (2021) DOI
Role of Platelets in Chronic Kidney Disease (2021) DOI

Federal Grants 1 $693,302 total

NIH/NIH Office of the Director Co-PI Jul 2022 - May 2027

Platelets in radiation-induced immune dysregulation

NIH Office of the Director $693,302 U01

Grants & Funding

Platelets in radiation-induced immune dysregulation NIH/Nat. Inst. of Allergy & Infectious Diseases Principal Investigator
Leukocyte-platelet modulation of the systemic inflammatory response NIH Principal Investigator
Transgenic analysis of platelet receptor expression NIH Principal Investigator
Murine Hemostatic Properties of Thrombosomes DHHS - Biomedical Advanced Research and Development Authority - Pass Through: Cellphire, Inc. Principal Investigator
In vivo, noninvasive, ultrasensitive photoacoustic detection of early breast cancer metastasis in bone US Department of the Army Principal Investigator
Characterization and Analysis of Platelet Septins NIH Principal Investigator
Murine Hemostatic Properties of Thrombosomes DHHS - Biomedical Advanced Research and Development Authority - Pass Through: Cellphire, Inc. Principal Investigator
Platelet-leukocyte regulation of inflammatory responses- Resubmission- Resubmission American Heart Association Co-Investigator