Steven J. Murdock
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Also affiliated: Virginia Commonwealth University (2020)
Research Areas
Biomedical Subjects
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Biography and Research Information
OverviewAI-generated summary
Steven J. Murdock's research focuses on understanding the molecular mechanisms of viral infections and the host immune response. He has investigated the role of tumor suppressor protein p53 in restricting gammaherpesvirus-driven germinal center B cell expansion during latency establishment. Murdock also studies how HIF-α activation impacts macrophage function during murine Leishmania major infection, exploring the molecular underpinnings of these interactions. His work also delves into the mechanisms of KSHV latency establishment and maintenance, as well as the potential implications of KSHV LANA in immune evasion by repressing productive viral replication and reducing adaptive immune activation. Murdock has published on topics including regulatory T cells and breast cancer progression, and the functional reprogramming of myeloid cells. His scholarship metrics include an h-index of 4 with 72 total citations across 9 publications. He has collaborated with several researchers at the University of Arkansas for Medical Sciences, including J. Craig Forrest and Mark Manzano.
Metrics
- h-index: 4
- Publications: 8
- Citations: 73
Selected Publications
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Repression of productive viral replication by KSHV LANA correlates with reduced adaptive immune activation: potential implications for KSHV immune evasion (2026)
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The amplitude of gammaherpesvirus lytic replication dictates adaptive immune activation: Potential implications for KSHV LANA in immune evasion (2026)
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Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment (2025)
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Molecular Mechanisms of KSHV Latency Establishment and Maintenance (2024)
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HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection (2021)
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HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection (2021)
Collaboration Network
Top Collaborators
- Molecular Mechanisms of KSHV Latency Establishment and Maintenance
- Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment
- Repression of productive viral replication by KSHV LANA correlates with reduced adaptive immune activation: potential implications for KSHV immune evasion
- Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment
- The amplitude of gammaherpesvirus lytic replication dictates adaptive immune activation: Potential implications for KSHV LANA in immune evasion
- Repression of productive viral replication by KSHV LANA correlates with reduced adaptive immune activation: potential implications for KSHV immune evasion
- Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment
- The amplitude of gammaherpesvirus lytic replication dictates adaptive immune activation: Potential implications for KSHV LANA in immune evasion
- Repression of productive viral replication by KSHV LANA correlates with reduced adaptive immune activation: potential implications for KSHV immune evasion
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
- Molecular Mechanisms of KSHV Latency Establishment and Maintenance
- Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Molecular Mechanisms of KSHV Latency Establishment and Maintenance
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