Michelle M. Vanlandingham
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Also affiliated: United States Food and Drug Administration (2010–2025)
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Michelle M. Vanlandingham's research focuses on the toxicological evaluation of bisphenol A (BPA), a compound found in various consumer products. Her work investigates the pharmacokinetic properties and tissue distribution of BPA in different life stages and species, including Sprague-Dawley rats, mice, and monkeys, with extrapolation to humans. Vanlandingham has published research on the effects of developmental exposure to BPA on spatial learning and memory in rats, as well as its impact on estrogen receptor expression in the juvenile and adult female rat hypothalamus.
Her research also involves comparing the internal dosimetry of BPA with other estrogenic compounds, such as ethinyl estradiol, to understand its mode of action. Vanlandingham has contributed to the NIEHS/FDA CLARITY-BPA research program. Her scholarship metrics include an h-index of 24, 42 total publications, and 1,753 total citations, designating her as a highly cited researcher. She has collaborated with several researchers at the National Center for Toxicological Research, including Frederick A. Beland, Luísa Camacho, Gonçalo Gamboa da Costa, and Volodymyr Tryndyak.
Metrics
- h-index: 24
- Publications: 42
- Citations: 1,759
Selected Publications
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Pharmacokinetics of cannabidiol and its metabolites in rhesus monkeys and New Zealand White rabbits (2025)
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Wastewater dataset on the SARS-CoV-2 sublineages circulating in Central Arkansas, USA, post-COVID-19 pandemic (2025)
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The effect of black cohosh extract and risedronate coadministration on bone health in an ovariectomized rat model (2024)
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Evaluating the toxicokinetics of some metabolites of a C6 polyfluorinated compound, 6:2 fluorotelomer alcohol in pregnant and nonpregnant rats after oral exposure to the parent compound (2023)
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Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice (2023)
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Route of Arsenic Exposure Differentially Impacts the Expression of Genes Involved in Gut-Mucosa-Associated Immune Responses and Gastrointestinal Permeability (2023)
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Investigation of microorganisms in cannabis after heating in a commercial vaporizer (2023)
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Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats (2022)
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In vivo localization and postmortem stability of benzo[a]pyrene‐DNA adducts (2019)
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Comparative pharmacokinetic and biodistribution study of two distinct squalene-containing oil-in-water emulsion adjuvants in H5N1 influenza vaccines (2019)
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A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results (2019)
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A single or short time repeated arsenic oral exposure in mice impacts mRNA expression for signaling and immunity related genes in the gut (2019)
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Metabolism and disposition of arsenic species from controlled dosing with dimethylarsinic acid (DMAV) in adult female CD-1 mice. V. Toxicokinetic studies following oral and intravenous administration (2019)
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Metabolism and disposition of arsenic species from oral dosing with sodium arsenite in neonatal CD-1 mice. IV. Toxicokinetics following gavage administration and lactational transfer (2018)
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Metabolism and disposition of arsenic species from controlled dosing with sodium arsenite in adult female CD-1 mice. III. Toxicokinetic studies following oral and intravenous administration (2018)
Collaboration Network
Top Collaborators
- Pharmacokinetics of bisphenol A in neonatal and adult Sprague-Dawley rats
- Distribution of bisphenol A into tissues of adult, neonatal, and fetal Sprague–Dawley rats
- Pharmacokinetic modeling: Prediction and evaluation of route dependent dosimetry of bisphenol A in monkeys with extrapolation to humans
- Comparison of Life-Stage-Dependent Internal Dosimetry for Bisphenol A, Ethinyl Estradiol, a Reference Estrogen, and Endogenous Estradiol to Test an Estrogenic Mode of Action in Sprague Dawley Rats
- Pharmacokinetics of Bisphenol A in neonatal and adult CD-1 mice: Inter-species comparisons with Sprague-Dawley rats and rhesus monkeys
Showing 5 of 19 shared publications
- Pharmacokinetics of bisphenol A in neonatal and adult Sprague-Dawley rats
- Distribution of bisphenol A into tissues of adult, neonatal, and fetal Sprague–Dawley rats
- NIEHS/FDA CLARITY-BPA research program update
- Pharmacokinetic modeling: Prediction and evaluation of route dependent dosimetry of bisphenol A in monkeys with extrapolation to humans
- Comparison of Life-Stage-Dependent Internal Dosimetry for Bisphenol A, Ethinyl Estradiol, a Reference Estrogen, and Endogenous Estradiol to Test an Estrogenic Mode of Action in Sprague Dawley Rats
Showing 5 of 17 shared publications
- Toxicity Evaluation of Bisphenol A Administered by Gavage to Sprague Dawley Rats From Gestation Day 6 Through Postnatal Day 90
- NIEHS/FDA CLARITY-BPA research program update
- Effects of developmental exposure to bisphenol A on spatial navigational learning and memory in rats: A CLARITY-BPA study
- Investigation of the Effects of Subchronic Low Dose Oral Exposure to Bisphenol A (BPA) and Ethinyl Estradiol (EE) on Estrogen Receptor Expression in the Juvenile and Adult Female Rat Hypothalamus
- Comparison of Life-Stage-Dependent Internal Dosimetry for Bisphenol A, Ethinyl Estradiol, a Reference Estrogen, and Endogenous Estradiol to Test an Estrogenic Mode of Action in Sprague Dawley Rats
Showing 5 of 13 shared publications
- Absorption and metabolism of triclosan after application to the skin of B 6 C 3 F 1 mice
- Role of peroxisome proliferator-activated receptor alpha (PPARα) and PPARα-mediated species differences in triclosan-induced liver toxicity
- Dose–response assessment of the dermal toxicity of triclosan in B6C3F1 mice
- Metabolism and disposition of arsenic species from controlled dosing with dimethylarsinic acid (DMAV) in adult female CD-1 mice. V. Toxicokinetic studies following oral and intravenous administration
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
Showing 5 of 13 shared publications
- Toxicity Evaluation of Bisphenol A Administered by Gavage to Sprague Dawley Rats From Gestation Day 6 Through Postnatal Day 90
- NIEHS/FDA CLARITY-BPA research program update
- Investigation of the Effects of Subchronic Low Dose Oral Exposure to Bisphenol A (BPA) and Ethinyl Estradiol (EE) on Estrogen Receptor Expression in the Juvenile and Adult Female Rat Hypothalamus
- Comparison of Life-Stage-Dependent Internal Dosimetry for Bisphenol A, Ethinyl Estradiol, a Reference Estrogen, and Endogenous Estradiol to Test an Estrogenic Mode of Action in Sprague Dawley Rats
- Lactational transfer of bisphenol A in Sprague–Dawley rats
Showing 5 of 9 shared publications
- Toxicity Evaluation of Bisphenol A Administered by Gavage to Sprague Dawley Rats From Gestation Day 6 Through Postnatal Day 90
- NIEHS/FDA CLARITY-BPA research program update
- Effects of developmental exposure to bisphenol A on spatial navigational learning and memory in rats: A CLARITY-BPA study
- Investigation of the Effects of Subchronic Low Dose Oral Exposure to Bisphenol A (BPA) and Ethinyl Estradiol (EE) on Estrogen Receptor Expression in the Juvenile and Adult Female Rat Hypothalamus
- A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results
Showing 5 of 9 shared publications
- NIEHS/FDA CLARITY-BPA research program update
- A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results
- Absorption and metabolism of triclosan after application to the skin of B 6 C 3 F 1 mice
- Effects of oral exposure to bisphenol A on gene expression and global genomic DNA methylation in the prostate, female mammary gland, and uterus of NCTR Sprague-Dawley rats
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
Showing 5 of 9 shared publications
- Pharmacokinetics of bisphenol A in neonatal and adult Sprague-Dawley rats
- Distribution of bisphenol A into tissues of adult, neonatal, and fetal Sprague–Dawley rats
- Pharmacokinetic modeling: Prediction and evaluation of route dependent dosimetry of bisphenol A in monkeys with extrapolation to humans
- Comparison of Life-Stage-Dependent Internal Dosimetry for Bisphenol A, Ethinyl Estradiol, a Reference Estrogen, and Endogenous Estradiol to Test an Estrogenic Mode of Action in Sprague Dawley Rats
- Pharmacokinetics of Bisphenol A in neonatal and adult CD-1 mice: Inter-species comparisons with Sprague-Dawley rats and rhesus monkeys
Showing 5 of 9 shared publications
- NIEHS/FDA CLARITY-BPA research program update
- Comparison of Life-Stage-Dependent Internal Dosimetry for Bisphenol A, Ethinyl Estradiol, a Reference Estrogen, and Endogenous Estradiol to Test an Estrogenic Mode of Action in Sprague Dawley Rats
- A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results
- Quantification of deuterated bisphenol A in serum, tissues, and excreta from adult Sprague‐Dawley rats using liquid chromatography with tandem mass spectrometry
- Metabolism and disposition of arsenic species from controlled oral dosing with sodium arsenite in adult female CD-1 mice. I. Pilot study to determine dosing, analytical measurements, and sampling strategies
Showing 5 of 7 shared publications
- A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results
- Role of peroxisome proliferator-activated receptor alpha (PPARα) and PPARα-mediated species differences in triclosan-induced liver toxicity
- Dose–response assessment of the dermal toxicity of triclosan in B6C3F1 mice
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents
Showing 5 of 6 shared publications
- Toxicity Evaluation of Bisphenol A Administered by Gavage to Sprague Dawley Rats From Gestation Day 6 Through Postnatal Day 90
- NIEHS/FDA CLARITY-BPA research program update
- A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results
- Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents
- The effect of black cohosh extract and risedronate coadministration on bone health in an ovariectomized rat model
- Toxicity Evaluation of Bisphenol A Administered by Gavage to Sprague Dawley Rats From Gestation Day 6 Through Postnatal Day 90
- NIEHS/FDA CLARITY-BPA research program update
- A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results
- Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents
- The effect of black cohosh extract and risedronate coadministration on bone health in an ovariectomized rat model
- Absorption and metabolism of triclosan after application to the skin of B 6 C 3 F 1 mice
- Role of peroxisome proliferator-activated receptor alpha (PPARα) and PPARα-mediated species differences in triclosan-induced liver toxicity
- Dose–response assessment of the dermal toxicity of triclosan in B6C3F1 mice
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice
- Toxicity Evaluation of Bisphenol A Administered by Gavage to Sprague Dawley Rats From Gestation Day 6 Through Postnatal Day 90
- A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents
- Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice
- Toxicity Evaluation of Bisphenol A Administered by Gavage to Sprague Dawley Rats From Gestation Day 6 Through Postnatal Day 90
- A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results
- Dose–response assessment of the dermal toxicity of triclosan in B6C3F1 mice
- Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents
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