Kartik Balachandran
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Professor
Also affiliated: University of Notre Dame (2008); Georgia Institute of Technology (2006–2011); University of Leeds (2022); Harvard University (2011–2014); University of Liverpool (2021–2022); Emory University (2009); Medical University of Silesia (2022); Washington University in St. Louis (1971); The Wallace H. Coulter Department of Biomedical Engineering (2006–2011); In-Q-Tel (2016); University of Belgrade (2023); Liverpool Heart and Chest Hospital (2021–2022); Laboratoire Informatique d'Avignon (2022); Silesian Center for Heart Disease (2022); Chelsea and Westminster Hospital (2024); Inspire Institute (2011); Leeds Dental Hospital (2022); Aalborg University (2021–2022)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Kartik Balachandran's research focuses on studying disease mechanisms and developing physiological models to investigate health conditions. He has received federal funding for two projects totaling $486,642. One grant, from the NIH/National Institute of Allergy and Infectious Diseases, awarded $436,642 for research into ACE2 SARS-CoV2-mediated valve disease using a microphysiological tissue-chip model. Another NSF grant of $50,000 supported his work on the translation potential of a co-cultured cardiomyocyte-on-a-chip heart model.
His recent publications explore a range of topics, including the breakdown of the blood-brain barrier and astrocyte reactivity after traumatic brain injury, and the use of label-free multiphoton microscopy for detecting calcific aortic valve disease. He has also investigated a three-dimensional valve-on-chip microphysiological system to understand early calcific aortic valve disease progression, the effect of mechanical strain on endothelial progenitor cells, and the development of a nasal airway-on-chip model. Further work examines the cellular microenvironment of aortic valves and the role of the local renin-angiotensin system in regulating cellular function within these valves.
Balachandran holds a high-impact researcher designation due to his significant citation count (2,785) and has published 89 total works, with an h-index of 26. He actively collaborates with researchers at the University of Arkansas at Fayetteville, including Ishita Tandon, Amanda Walls, Gustavo Vaca-Diez, and Denise Fabiano do Nascimento.
Metrics
- h-index: 26
- Publications: 90
- Citations: 2,800
Selected Publications
-
Characterization of Human Aortic Valve Cells isolated from Calcified Aortic Valve Replacement Explants: Implications for Calcific Aortic Valve Disease Research (2026)
-
Development of a nasal airway-on-chip co-culture model to study particulate matter exposure (2026)
-
Characterizing Piezoelectric‐Blended Polydimethylsiloxane for Use as a Mechanoelectrical Responsive Cell Culture Substrate (2025)
-
Elucidating the mechanosensitive pathways of physiological and pathological strain on valve cells in a novel human valve-on-chip system (2025)
-
The future is fully defined: recombinant fragment E8 of laminin-511 is a viable xenofree alternative to Matrigel for hiPSC culture and differentiation into neurovascular cell types (2024)
-
The effect of traumatic injuries on the nervous system (2024)
-
Contributors (2024)
-
A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression (2024)
-
A nasal airway-on-chip model to evaluate airflow pre-conditioning during epithelial cell maturation at the air-liquid interface (2024)
-
The future is fully defined: recombinant fragment E8 of laminin-511 is a viable xenofree alternative to Matrigel for hiPSC culture and differentiation into neurovascular cell types (2024)
-
A Three-Dimensional Valve-on-Chip Microphysiological System Reveals Novel Biomarkers of Early Calcific Aortic Valve Disease Progression (2023)
-
Functional Analysis of the Cortical Transcriptome and Proteome Reveal Neurogenesis, Inflammation, and Cell Death after Repeated Traumatic Brain Injury <i>In vivo</i> (2022)
-
Effect of Cyclic Uniaxial Mechanical Strain on Endothelial Progenitor Cell Differentiation (2022)
-
Aortic valve cell microenvironment: Considerations for developing a valve-on-chip (2021)
-
Local Renin-Angiotensin System Signaling Mediates Cellular Function of Aortic Valves (2021)
Federal Grants 2 $486,642 total
ACE2 SARS-CoV2-mediated valve disease in a microphysiological tissue-chip model
I-Corps: Translation Potential of a Co-cultured Cardiomyocyte-on-a-Chip Heart Model Platform
Collaboration Network
Top Collaborators
- Label-Free Multiphoton Microscopy for the Detection and Monitoring of Calcific Aortic Valve Disease
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
- Effect of Cyclic Uniaxial Mechanical Strain on Endothelial Progenitor Cell Differentiation
- Aortic valve cell microenvironment: Considerations for developing a valve-on-chip
- Local Renin-Angiotensin System Signaling Mediates Cellular Function of Aortic Valves
Showing 5 of 9 shared publications
- Functional Analysis of the Cortical Transcriptome and Proteome Reveal Neurogenesis, Inflammation, and Cell Death after Repeated Traumatic Brain Injury <i>In vivo</i>
- The future is fully defined: recombinant fragment E8 of laminin-511 is a viable xenofree alternative to Matrigel for hiPSC culture and differentiation into neurovascular cell types
- Contributors
- The effect of traumatic injuries on the nervous system
- The future is fully defined: recombinant fragment E8 of laminin-511 is a viable xenofree alternative to Matrigel for hiPSC culture and differentiation into neurovascular cell types
Showing 5 of 6 shared publications
- Label-Free Multiphoton Microscopy for the Detection and Monitoring of Calcific Aortic Valve Disease
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
- A Three-Dimensional Valve-on-Chip Microphysiological System Reveals Novel Biomarkers of Early Calcific Aortic Valve Disease Progression
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
- A Three-Dimensional Valve-on-Chip Microphysiological System Reveals Novel Biomarkers of Early Calcific Aortic Valve Disease Progression
- Elucidating the mechanosensitive pathways of physiological and pathological strain on valve cells in a novel human valve-on-chip system
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
- The future is fully defined: recombinant fragment E8 of laminin-511 is a viable xenofree alternative to Matrigel for hiPSC culture and differentiation into neurovascular cell types
- The future is fully defined: recombinant fragment E8 of laminin-511 is a viable xenofree alternative to Matrigel for hiPSC culture and differentiation into neurovascular cell types
- The future is fully defined: recombinant fragment E8 of laminin-511 is a viable xenofree alternative to Matrigel for hiPSC culture and differentiation into neurovascular cell types
- The future is fully defined: recombinant fragment E8 of laminin-511 is a viable xenofree alternative to Matrigel for hiPSC culture and differentiation into neurovascular cell types
- Characterizing Piezoelectric‐Blended Polydimethylsiloxane for Use as a Mechanoelectrical Responsive Cell Culture Substrate
- Blood–Brain Barrier Breakdown and Astrocyte Reactivity Evident in the Absence of Behavioral Changes after Repeated Traumatic Brain Injury
- Functional Analysis of the Cortical Transcriptome and Proteome Reveal Neurogenesis, Inflammation, and Cell Death after Repeated Traumatic Brain Injury <i>In vivo</i>
- Blood–Brain Barrier Breakdown and Astrocyte Reactivity Evident in the Absence of Behavioral Changes after Repeated Traumatic Brain Injury
- Functional Analysis of the Cortical Transcriptome and Proteome Reveal Neurogenesis, Inflammation, and Cell Death after Repeated Traumatic Brain Injury <i>In vivo</i>
- Blood–Brain Barrier Breakdown and Astrocyte Reactivity Evident in the Absence of Behavioral Changes after Repeated Traumatic Brain Injury
- Functional Analysis of the Cortical Transcriptome and Proteome Reveal Neurogenesis, Inflammation, and Cell Death after Repeated Traumatic Brain Injury <i>In vivo</i>
- Aortic valve cell microenvironment: Considerations for developing a valve-on-chip
- Local Renin-Angiotensin System Signaling Mediates Cellular Function of Aortic Valves
- Effect of Cyclic Uniaxial Mechanical Strain on Endothelial Progenitor Cell Differentiation
- Aortic valve cell microenvironment: Considerations for developing a valve-on-chip
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
- A Three-Dimensional Valve-on-Chip Microphysiological System Reveals Novel Biomarkers of Early Calcific Aortic Valve Disease Progression
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
- A Three-Dimensional Valve-on-Chip Microphysiological System Reveals Novel Biomarkers of Early Calcific Aortic Valve Disease Progression
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
- A Three-Dimensional Valve-on-Chip Microphysiological System Reveals Novel Biomarkers of Early Calcific Aortic Valve Disease Progression
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
- A Three-Dimensional Valve-on-Chip Microphysiological System Reveals Novel Biomarkers of Early Calcific Aortic Valve Disease Progression
Similar Researchers
Based on overlapping research topics