Matthew D. Thompson

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Assistant Professor

UAMS

Also affiliated: National Institutes of Health (2015–2017); United States Food and Drug Administration (2019–2024); Center for Drug Evaluation and Research (2019–2025); University of Louisville (2019); Texas Woman's University (2009); Lyon College (2025); University of Washington (2004); Medical College of Wisconsin (2009–2012); Cornell University (2025); Leeds Teaching Hospitals NHS Trust (2019–2024); Bexley Hall (2024); St James's University Hospital (2020); University of Arkansas Community College at Batesville (2025); IQVIA (United Kingdom) (2018–2023); Universidad Real (2024); National Cancer Institute (2012–2017); Center for Cancer Research (2014); New York State College of Veterinary Medicine (2025); Washington State University (2020); Colorado State University (2008–2010); KU Leuven (2013)

Faculty Researcher

17 h-index 77 pubs 890 cited

Research Areas

Biomedical Subjects

Links

ORCID

OverviewAI-generated summary

Matthew D. Thompson's research focuses on understanding cancer treatment patterns and outcomes, particularly for non-small cell lung cancer. He has investigated trends in systemic anticancer therapy prescriptions and their correlation with mortality in advanced non-small cell lung cancer patients using real-world data from the I-O Optimise initiative. His work also extends to assessing the use of bone-targeting agents in patients with bone metastases from breast, lung, or prostate cancer, utilizing both structured and unstructured electronic health records.

Thompson also explores fundamental biological mechanisms, including the role and regulation of Pif1 family helicases at the replication fork and structural features of helicases that influence their DNA interaction. His publication record includes work on multi-omics data integration for triple-negative breast cancer and the application of CUT&Tag technology for sequence identification. He has a publication record of 77 papers and an h-index of 17, with 884 citations. Thompson collaborates with several researchers at the University of Arkansas for Medical Sciences, including Alicia K. Byrd and Maroof K. Zafar.

Metrics

h-index: 17
Publications: 77
Citations: 890

Selected Publications

Untargeted CUT&Tag reads are enriched at accessible chromatin and restrict identification of potential G4-forming sequences in G4-targeted CUT&Tag experiments (2025)

Nucleic Acids Research 8 citations DOI OpenAlex
Rare SNP in the HELB gene interferes with RPA interaction and cellular function of HELB (2025)

NAR Molecular Medicine DOI OpenAlex
Untargeted CUT&Tag and BG4 CUT&Tag are both enriched at G-quadruplexes and accessible chromatin (2024)

bioRxiv (Cold Spring Harbor Laboratory) 3 citations DOI OpenAlex
Rare SNP in the HELB gene interferes with RPA interaction and cellular function of HELB (2024)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
Role and Regulation of Pif1 Family Helicases at the Replication Fork (2022)

International Journal of Molecular Sciences 14 citations DOI OpenAlex
Monitoring helicase-catalyzed unwinding of multiple duplexes simultaneously (2022)

Methods in enzymology on CD-ROM/Methods in enzymology DOI OpenAlex
A structural feature of Dda helicase which enhances displacement of streptavidin and trp repressor from <scp>DNA</scp> (2021)

Protein Science 8 citations DOI OpenAlex
Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer (2021)

Molecular Omics 17 citations DOI OpenAlex