Maroof Zafar
Research Program Manager
University of Arkansas for Medical Sciences
staff
Biochemistry & Molecular Biology, College of Medicine
Research Areas
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Biography and Research Information
OverviewAI-generated summary
Maroof Zafar's research investigates molecular mechanisms underlying cancer development and treatment. His work includes studies on triple-negative breast cancer, focusing on multi-omics data integration to identify regulatory features. He has also examined the role of specific enzymes, such as tryptophan 2,3-dioxygenase, in DNA damage tolerance and repair in glioma cells, and the function of DNA polymerase kappa in glioblastoma replication. Zafar's publications also address the impact of genetic variations, like rare SNPs in the HELB gene, on cellular function and protein interactions. He has collaborated with researchers from the University of Arkansas for Medical Sciences and Lyon College on multiple shared publications.
Metrics
- h-index: 15
- Publications: 33
- Citations: 666
Selected Publications
- Rare SNP in the <i>HELB</i> gene interferes with RPA interaction and cellular function of HELB (2025) DOI
- Rare SNP in the <i>HELB</i> gene interferes with RPA interaction and cellular function of HELB (2024) DOI
- Anti-Programmed Death Ligand-1 Induced Acute Vision Loss in a Patient With Cancer-Associated Retinopathy (2022) DOI
- A structural feature of Dda helicase which enhances displacement of streptavidin and <i>trp</i> repressor from <scp>DNA</scp> (2021) DOI
- Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer (2021) DOI
- DNA Polymerase Kappa Acts as a Barrier to Unrestrained Replication in Glioblastoma (2021) DOI
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells (2021) DOI
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