Stepan Melnyk
Professor
Also affiliated: Louisiana State University (1999); Arkansas Children's Hospital (1999–2024); NewYork–Presbyterian Brooklyn Methodist Hospital (2003); University of British Columbia (2003–2006); Cornell University (2003); Saginaw Valley State University (1999); Arkansas Cardiology (2006); Tampere University (2002); Arkansas Children's Nutrition Center (2020–2024); Arkansas Department of Agriculture (2006); National Technical University "Kharkiv Polytechnic Institute" (2017); University of California, Davis (2002); Lviv Polytechnic National University (2013–2023)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Stepan Melnyk's research program focuses on the molecular mechanisms underlying disease, particularly in the areas of epigenetics, oxidative stress, and metabolism. He has investigated the role of DNA methylation and redox imbalance in early childhood obesity and their association with Autism Spectrum Disorder (ASD) outcomes, utilizing both targeted and untargeted metabolomics in human and animal models. His work includes a randomized controlled trial examining sulforaphane and metabolite discovery in children with ASD.
Melnyk also studies the impact of oxidative stress on various disease states. His publications include work on enhancer-activated RET conferring protection against oxidative stress in acute myeloid leukemia and examining associations between prenatal biomarkers of oxidative stress and offspring neurodevelopmental outcomes. He has also investigated methods for inducing and assessing intestinal permeability in rodent models of radiation injury.
With an h-index of 55 and over 10,900 citations across 171 publications, Melnyk is recognized as a highly cited researcher. His collaborations at the University of Arkansas for Medical Sciences include work with Igor Koturbash, Reza Hakkak, S. Jill James, and Martin Hauer‐Jensen.
Metrics
- h-index: 55
- Publications: 171
- Citations: 11,015
Selected Publications
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Exposure to a Single Dose of Space-Relevant Proton Radiation Alters the Intestinal One-Carbon Metabolism Pathway and Microbiome in Mice (2025)
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The association between prenatal oxidative stress levels measured by isoprostanes and offspring neurodevelopmental outcomes at 36 months (2024)
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Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression (2022)
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Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder (2021)
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Altered Metabolism of Mothers of Young Children with Autism Spectrum Disorder: A Case Control Study (2020)
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Altered Metabolism of Mothers of Young Children with Autism Spectrum Disorder: A Case Control Study (2020)
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Altered Metabolism of Mothers of Young Children with Autism Spectrum Disorder: A Case Control Study (2020)
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Altered Metabolism of Mothers of Young Children with Autism Spectrum Disorder: A Case Control Study (2020)
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Altered Metabolism of Mothers of Young Children with Autism Spectrum Disorder: A Case Control Study (2020)
Collaboration Network
Top Collaborators
- Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder
- Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression
- The association between prenatal oxidative stress levels measured by isoprostanes and offspring neurodevelopmental outcomes at 36 months
- Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression
- The association between prenatal oxidative stress levels measured by isoprostanes and offspring neurodevelopmental outcomes at 36 months
- Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression
- The association between prenatal oxidative stress levels measured by isoprostanes and offspring neurodevelopmental outcomes at 36 months
- Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression
- The association between prenatal oxidative stress levels measured by isoprostanes and offspring neurodevelopmental outcomes at 36 months
- Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression
- The association between prenatal oxidative stress levels measured by isoprostanes and offspring neurodevelopmental outcomes at 36 months
- Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression
- The association between prenatal oxidative stress levels measured by isoprostanes and offspring neurodevelopmental outcomes at 36 months
- Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder
- Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder
- Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder
- Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder
- Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder
- Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder
- Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder
- Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder
- Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder
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