Xinyu Li

High Impact

Researcher

University of Arkansas

Faculty Researcher

43 h-index 372 pubs 5,893 cited

Upstream record may be merged OpenAlex, the source of these figures, lists 191 institutions in 7 countries for this author record — a pattern that usually means it combines several researchers with similar names. The totals above may include work by other people.

Research Areas

Biomedical Subjects

Links

ORCID

OverviewAI-generated summary

Xinyu Li's research focuses on the intricate roles of extracellular vesicles, particularly exosomes, within the tumor microenvironment (TME) and their implications for cancer immunotherapy. Her work investigates how these vesicles, released by tumor cells, influence cellular signaling, immune responses, and angiogenesis, exploring their potential as therapeutic targets and delivery vehicles. Li has also examined the metabolic vulnerabilities of cancer cells, specifically "glutamine addiction," and its regulation by oncogenes, considering its relevance to clinical treatment strategies.

Further research interests include the mechanisms of viral entry and cell fusion, as exemplified by studies on the SARS-CoV-2 spike protein. Li also contributes to the understanding of cellular components like mast cells in the context of colorectal cancer progression and has explored advanced biomedical applications, such as the development of individualized porous implants for bone defect treatment using three-dimensional printing. Her work is characterized by a broad engagement with molecular mechanisms underlying disease and potential therapeutic interventions.

Metrics

h-index: 43
Publications: 372
Citations: 5,893

Selected Publications

Expanding the Genetic Code with Lysine Aminoacylation (2026)

DOI OpenAlex
Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655 (2026)

DOI OpenAlex
Functional consequences of lysine acetylation of phosphofructokinase isozymes (2025)

FEBS Journal 4 citations DOI OpenAlex
Characterizing lysine acetylation of glucokinase (2023)

Protein Science 5 citations DOI OpenAlex