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Presence
Current · Arkansas
Last published
2022
Sources
OpenAlex · ORCID
Refreshed
2026-10-07
R
Ralph E. Patton
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Also affiliated: Tulane University (1996); United States Food and Drug Administration (2013); Charles River Laboratories (United States) (2005)
10 h-index
17 pubs
355 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Ralph E. Patton's research focuses on toxicological studies, primarily utilizing rodent models. His work has investigated the toxicity of various compounds, including high-molecular-weight polyethylene glycols and the carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Patton has conducted dose-response relationship studies and inhalation toxicity assessments, such as 14-day and 90-day nose-only inhalation studies of NNK in Sprague-Dawley rats. He has also explored the pharmacokinetic aspects of drug transfer across the placenta in pregnant rats, examining drugs with different physicochemical properties. Patton's scholarship metrics include an h-index of 10, with 17 total publications and 342 citations. He has collaborated with several colleagues at the National Center for Toxicological Research, including Mackean P. Maisha, Matthew Bryant, Robert P. Felton, and Seonggi Min, co-authoring multiple publications with them.
Metrics
- h-index: 10
- Publications: 17
- Citations: 355
Selected Publications
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Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats (2022)
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90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats (2021)
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14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats (2021)
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Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents (2016)
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Dose–response assessment of the dermal toxicity of triclosan in B6C3F1 mice (2015)
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Serum myoglobin, but not lipopolysaccharides, is predictive of AMPH-induced striatal neurotoxicity (2013)
Collaboration Network
Top Collaborators
Robert P. Felton
National Center for Toxicological Research
4 shared publications
In database
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
Kelly J. Davis
National Center for Toxicological Research
3 shared publications
In database
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- Serum myoglobin, but not lipopolysaccharides, is predictive of AMPH-induced striatal neurotoxicity
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
Michelle M. Vanlandingham
National Center for Toxicological Research
3 shared publications
In database
- Dose–response assessment of the dermal toxicity of triclosan in B6C3F1 mice
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents
Greg R. Olson
National Center for Toxicological Research
3 shared publications
In database
- Dose–response assessment of the dermal toxicity of triclosan in B6C3F1 mice
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents
Sherry M. Lewis
National Center for Toxicological Research
3 shared publications
In database
- Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
Estatira Sepehr
National Center for Toxicological Research (US)
3 shared publications
- Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
Matthew Bryant
National Center for Toxicological Research
3 shared publications
In database
- Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
Mackean P. Maisha
National Center for Toxicological Research
3 shared publications
In database
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
Jia‐Long Fang
National Center for Toxicological Research
2 shared publications
In database
- Dose–response assessment of the dermal toxicity of triclosan in B6C3F1 mice
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
Beth Elisa Juliar
2 shared publications
- Dose–response assessment of the dermal toxicity of triclosan in B6C3F1 mice
- Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents
Frederick A. Beland
National Center for Toxicological Research
2 shared publications
In database
- Dose–response assessment of the dermal toxicity of triclosan in B6C3F1 mice
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
Gonçalo Gamboa da Costa
National Center for Toxicological Research
2 shared publications
In database
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents
Mallikarjuna Shivapura Basavarajappa
National Center for Toxicological Research (US)
2 shared publications
- Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
Shu-Chieh Hu
National Center for Toxicological Research
2 shared publications
In database
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
Seonggi Min
National Center for Toxicological Research
2 shared publications
In database
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
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