Ralph E. Patton

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Researcher

NCTR

Also affiliated: Tulane University (1996); United States Food and Drug Administration (2013); Charles River Laboratories (United States) (2003–2005)

Faculty Researcher

10 h-index 17 pubs 347 cited

Research Areas

Biomedical Subjects

OverviewAI-generated summary

Ralph E. Patton's research focuses on toxicological studies, primarily utilizing rodent models. His work has investigated the toxicity of various compounds, including high-molecular-weight polyethylene glycols and the carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Patton has conducted dose-response relationship studies and inhalation toxicity assessments, such as 14-day and 90-day nose-only inhalation studies of NNK in Sprague-Dawley rats. He has also explored the pharmacokinetic aspects of drug transfer across the placenta in pregnant rats, examining drugs with different physicochemical properties. Patton's scholarship metrics include an h-index of 10, with 17 total publications and 342 citations. He has collaborated with several colleagues at the National Center for Toxicological Research, including Mackean P. Maisha, Matthew Bryant, Robert P. Felton, and Seonggi Min, co-authoring multiple publications with them.

Metrics

h-index: 10
Publications: 17
Citations: 347

Selected Publications

Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats (2022)

Toxicology Letters 22 citations DOI OpenAlex
90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats (2021)

Food and Chemical Toxicology 6 citations DOI OpenAlex
14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats (2021)

Toxicological Sciences 7 citations DOI OpenAlex
Characterization of the variability in the extent of nonalcoholic fatty liver induced by a high‐fat diet in the genetically diverse Collaborative Cross mouse model (2020)

The FASEB Journal 33 citations DOI OpenAlex
Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents (2016)

Food and Chemical Toxicology 16 citations DOI OpenAlex
Dose–response assessment of the dermal toxicity of triclosan in B6C3F1 mice (2015)

Toxicology Research 24 citations DOI OpenAlex
Serum myoglobin, but not lipopolysaccharides, is predictive of AMPH-induced striatal neurotoxicity (2013)

NeuroToxicology 6 citations DOI OpenAlex