Tiffany Weinkopff
Assistant Professor
Also affiliated: University of Maryland, Baltimore (2018); Centers for Disease Control and Prevention (2014); University of Georgia (2009–2014); University of Arkansas Medical Center (2024); World Health Organization (2014–2015); Division of Parasitic Diseases and Malaria (2014); University of Pennsylvania (2015–2016); University of Lausanne (2012–2015)
Microbiology & Immunology, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Tiffany Weinkopff is an Assistant Professor in the Department of Microbiology & Immunology at the University of Arkansas for Medical Sciences. Her research focuses on understanding the host-pathogen interactions during parasitic infections, particularly cutaneous leishmaniasis. Weinkopff investigates how the host immune system responds to infection by *Leishmania major*, employing single-cell resolution techniques to analyze cellular heterogeneity and transcriptomic profiling in infected mice.
Her work has explored the role of signaling pathways, such as Hypoxia-Inducible Factor (HIF) signaling, in modulating macrophage function and promoting lymphangiogenesis during infection. She also studies the impact of the inflammatory microenvironment on macrophage transcriptional remodeling in leishmanial lesions. Weinkopff has published 40 papers, accumulating 679 citations and an h-index of 14. Her recent collaborations include work with Charity L. Washam, Manjunath Bettadapura, Steven Murdock, and Hayden Roys, all at the University of Arkansas for Medical Sciences.
Metrics
- h-index: 15
- Publications: 42
- Citations: 720
Positions
-
Associate Professor 2026–presentUniversity of Arkansas for Medical Sciences Microbiology and Immunology ORCID
-
Assistant Professor 2017–presentUniversity of Arkansas for Medical Sciences Microbiology & Immunology, College of Medicine Institutional directory
-
Postdoc publications 2015–2016University of Pennsylvania ORCID
-
Postdoctoral Fellow 2013–2017University of Pennsylvania Pathobiology ORCID
-
Postdoctoral Fellow 2010–2012University of Lausanne Department de Biochemie ORCID
-
Summer Scholar Program 2003Eastern Virginia Medical School Pediatric Research Center for Pediatric Research ORCID
-
Undergraduate Summer Research Training Program 2002National Institute of Diabetes and Digestive and Kidney Diseases Laboratory of Biochemistry and Genetics ORCID
Selected Publications
-
Guanylate-binding proteins balance iNOS/Arg-1 in myeloid cells during L. major infection and promote host defense to infection (2026)
-
Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis 4267 (2025)
-
Impaired lymphatic remodeling leads to immunopathology during non-healing cutaneous leishmaniasis 4376 (2025)
-
From defense to disease: the multifaceted role of lymphatics during infection (2025)
-
Guanylate-Binding Proteins Promote Host Defense Against Leishmania major by Balancing iNOS/Arg-1 in Myeloid Cells (2025)
-
Dysregulated lymphatic remodeling promotes immunopathology during non-healing cutaneous leishmaniasis (2025)
-
Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis (2025)
-
HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection (2025)
-
Platelets Modulate Leukocyte Population Composition Within Perivascular Adipose Tissue (2025)
-
Host guanylate binding proteins participate in parasite control during Leishmania infection (2024)
-
HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection (2024)
-
Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs (2024)
-
Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis (2024)
-
Metabolically active neutrophils represent a permissive niche for Mycobacterium tuberculosis (2024)
-
Investigating the platelet contribution to diet induced PVAT leukocyte infiltration (2024)
Research Interests
Leishmania, leishmaniasis, lymphatics, macrophages, vascular remodeling
Grants & Funding
As listed on this researcher's institutional profile.
- Partnerships for Biomedical Research in Arkansas - Admin Supplement NIH/Nat. Inst. of General Medical Sciences Principal Investigator
- Partnerships for Biomedical Research in Arkansas NIH Co-Investigator
- The Role of Myeloid Lineage Cells in Leishmaniasis NIH Principal Investigator
- Regulation of macrophage function during acute infection with Plasmodium NIH Co-Investigator
Collaboration Network
Top Collaborators
- Leishmania Infection Induces Macrophage Vascular Endothelial Growth Factor A Production in an ARNT/HIF-Dependent Manner
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
Showing 5 of 19 shared publications
- Leishmania Infection Induces Macrophage Vascular Endothelial Growth Factor A Production in an ARNT/HIF-Dependent Manner
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
Showing 5 of 19 shared publications
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
Showing 5 of 16 shared publications
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
Showing 5 of 13 shared publications
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
- In vivo reprogramming of murine host immune response genes following Leishmania major infection
Showing 5 of 10 shared publications
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
Showing 5 of 9 shared publications
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
- In vivo reprogramming of murine host immune response genes following Leishmania major infection
Showing 5 of 8 shared publications
- Lymphatic Type 1 Interferon Responses Are Critical for Control of Systemic Reovirus Dissemination
- Lymphatic type-1 interferon responses are critical for control of systemic reovirus dissemination
- Abstract 11421: The M2 Gene is a Determinant of Reovirus-Induced Myocarditis
- Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs
- From defense to disease: the multifaceted role of lymphatics during infection
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis
- Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis 4267
- Lymphatic Type 1 Interferon Responses Are Critical for Control of Systemic Reovirus Dissemination
- Lymphatic type-1 interferon responses are critical for control of systemic reovirus dissemination
- Abstract 11421: The M2 Gene is a Determinant of Reovirus-Induced Myocarditis
- Lymphatic Type 1 Interferon Responses Are Critical for Control of Systemic Reovirus Dissemination
- Lymphatic type-1 interferon responses are critical for control of systemic reovirus dissemination
- Abstract 11421: The M2 Gene is a Determinant of Reovirus-Induced Myocarditis
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection
- Leishmania Infection Induces Macrophage Vascular Endothelial Growth Factor A Production in an ARNT/HIF-Dependent Manner
- Erratum for Weinkopff et al., “ Leishmania Infection Induces Macrophage Vascular Endothelial Growth Factor A Production in an ARNT/HIF-Dependent Manner”
- Lymphatic Type 1 Interferon Responses Are Critical for Control of Systemic Reovirus Dissemination
- Lymphatic type-1 interferon responses are critical for control of systemic reovirus dissemination
Similar Researchers
Based on overlapping research topics