Alexx Weaver

Researcher

UAMS primary Arkansas State University

Also affiliated: Arkansas Biosciences Institute (2023–2024)

Faculty Researcher

2 h-index 10 pubs 15 cited

Research Areas

Biomedical Subjects

OverviewAI-generated summary

Alexx Weaver's research has focused on the molecular mechanisms underlying disease, particularly leishmaniasis and breast cancer. Weaver has investigated the role of enhanced translational activity in lymphatic endothelial cell activation in cutaneous leishmaniasis, a parasitic disease transmitted by sandflies. This work has involved studying disease models in animals and exploring potential therapeutic compounds. Weaver's publications also include investigations into the anticancer effects of plant-derived compounds, such as arachidin-1 and stilbene-rich extracts, in combination with paclitaxel for triple-negative and hormone receptor-positive breast cancer cells. These studies explore how these compounds enhance the efficacy of chemotherapy and elucidate their mechanisms of action. Weaver collaborates with researchers at the University of Arkansas for Medical Sciences, including Hayden Roys, Anne K. Bowlin, and Lucy Fry, as well as Fabricio Medina-Bolívar at Arkansas State University.

Metrics

h-index: 2
Publications: 10
Citations: 15

Selected Publications

Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis 4267 (2025)

The Journal of Immunology DOI OpenAlex
Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis (2025)

Lymphatic Research and Biology 1 citation DOI OpenAlex
Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs (2024)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis (2024)

bioRxiv (Cold Spring Harbor Laboratory) 2 citations DOI OpenAlex
Stilbene-rich extract increases the cytotoxic effects of paclitaxel in hormone receptor-positive and triple-negative breast cancer spheroids (2024)

Phytomedicine Plus DOI OpenAlex
Arachidin-1, a Prenylated Stilbenoid from Peanut, Enhances the Anticancer Effects of Paclitaxel in Triple-Negative Breast Cancer Cells (2023)

Cancers 12 citations DOI OpenAlex
Elucidating the Anticancer Mechanism of Arachidin‐1 in Triple‐Negative Breast Cancer Cells (2022)

The FASEB Journal DOI OpenAlex
Prenylated Stilbenoids as Potential Adjuvants for Paclitaxel in the Treatment of Triple‐Negative Breast Cancer (2022)

The FASEB Journal DOI OpenAlex