Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Manjunath Bettadapura's research focuses on the molecular mechanisms underlying host-pathogen interactions, particularly in the context of leishmaniasis. His work investigates how signaling pathways within macrophages influence disease progression and the host's immune response. Bettadapura has studied the role of hypoxia-inducible factor (HIF) signaling in macrophages during infection with *Leishmania major*, a parasite responsible for cutaneous leishmaniasis.
His publications explore how HIF-alpha activation impacts macrophage function and contributes to lymphangiogenesis, the formation of new lymphatic vessels, in murine models of infection. These studies aim to elucidate the cellular and molecular events that govern the susceptibility and response to *Leishmania major* infection. Bettadapura has collaborated with researchers at the University of Arkansas for Medical Sciences and the University of Arkansas at Pine Bluff on these investigations.
Metrics
- h-index: 2
- Publications: 3
- Citations: 41
Selected Publications
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HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection (2021)
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HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection (2021)
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Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection (2021)
Collaboration Network
Top Collaborators
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
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