Match tier
Listed
Presence
Current · Arkansas
Last published
2021
Sources
OpenAlex · ORCID
Refreshed
2026-10-08
A
April C.L. Bostian
Role not yet determined Is this you? Add your title
Also affiliated: University of Arkansas Medical Center (2013–2016); Arkansas Biosciences Institute (2017)
4 h-index
8 pubs
81 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
April C.L. Bostian investigates the molecular mechanisms underlying cancer, with a recent focus on glioma cells. Her work examines the role of tryptophan 2,3-dioxygenase (TDO) and its impact on DNA damage tolerance and repair pathways within these cells. Bostian's research has shown that inhibiting TDO can impair these critical cellular processes in glioma, suggesting potential therapeutic avenues. Her scholarship metrics include an h-index of 4, with a total of 8 publications and 77 citations. She has collaborated with researchers at the University of Arkansas for Medical Sciences, including Amit Ketkar, Robert L. Eoff, Maroof K. Zafar, and Alan J. Tackett, on shared publications.
Metrics
- h-index: 4
- Publications: 8
- Citations: 81
Selected Publications
-
Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells (2021)
-
Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells (2020)
-
Inhibition of Kynurenine Signaling Decreases Glioblastoma Multiforme Genomic Instability and Sensitizes Cells to Chemotherapeutic Treatment (2017)
-
Aberrant Kynurenine Signaling Modulates DNA Replication Stress Factors and Promotes Genomic Instability in Gliomas (2016)
-
Dioxol and dihydrodioxin analogs of 2- and 3-phenylacetonitriles as potent anti-cancer agents with nanomolar activity against a variety of human cancer cells (2016)
-
Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells (2015)
Collaboration Network
Top Collaborators
Robert L. Eoff
University of Arkansas for Medical Sciences
6 shared publications
In database
- Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
- Aberrant Kynurenine Signaling Modulates DNA Replication Stress Factors and Promotes Genomic Instability in Gliomas
- Dioxol and dihydrodioxin analogs of 2- and 3-phenylacetonitriles as potent anti-cancer agents with nanomolar activity against a variety of human cancer cells
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
Showing 5 of 6 shared publications
Leena Maddukuri
University of Arkansas for Medical Sciences
4 shared publications
In database
- Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
- Inhibition of Kynurenine Signaling Decreases Glioblastoma Multiforme Genomic Instability and Sensitizes Cells to Chemotherapeutic Treatment
Megan R. Reed
University of Arkansas for Medical Sciences
4 shared publications
In database
- Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
- Inhibition of Kynurenine Signaling Decreases Glioblastoma Multiforme Genomic Instability and Sensitizes Cells to Chemotherapeutic Treatment
Amit Ketkar
University of Arkansas for Medical Sciences
3 shared publications
In database
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
- Dioxol and dihydrodioxin analogs of 2- and 3-phenylacetonitriles as potent anti-cancer agents with nanomolar activity against a variety of human cancer cells
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
Maroof K. Zafar
University of Arkansas for Medical Sciences
3 shared publications
In database
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
- Inhibition of Kynurenine Signaling Decreases Glioblastoma Multiforme Genomic Instability and Sensitizes Cells to Chemotherapeutic Treatment
Stephanie D. Byrum
Arkansas Children's Hospital
2 shared publications
In database
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
Alan J. Tackett
Arkansas Children's Hospital
2 shared publications
In database
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
- Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
Tatsiana Savenka
University of Arkansas for Medical Sciences (US)
1 shared publication
- Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells
Jessica H. Hartman
University of Arkansas for Medical Sciences (US)
1 shared publication
- Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells
Lauren Evoy Davis
University of Arkansas for Medical Sciences (US)
1 shared publication
- Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells
Dakota L. Pouncey
University of Arkansas for Medical Sciences
1 shared publication
In database
- Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells
Grover P. Miller
University of Arkansas for Medical Sciences
1 shared publication
In database
- Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells
Nikhil Reddy Madadi
University of Arkansas for Medical Sciences (US)
1 shared publication
- Dioxol and dihydrodioxin analogs of 2- and 3-phenylacetonitriles as potent anti-cancer agents with nanomolar activity against a variety of human cancer cells
Narsimha Reddy Penthala
University of Arkansas for Medical Sciences
1 shared publication
In database
- Dioxol and dihydrodioxin analogs of 2- and 3-phenylacetonitriles as potent anti-cancer agents with nanomolar activity against a variety of human cancer cells
Peter A. Crooks
University of Arkansas for Medical Sciences
1 shared publication
In database
- Dioxol and dihydrodioxin analogs of 2- and 3-phenylacetonitriles as potent anti-cancer agents with nanomolar activity against a variety of human cancer cells
Similar Researchers
Based on overlapping research topics
Andres A. Caro
Hendrix College
Cancer-related molecular mechanisms research
Disease Mechanisms Research
Metabolism and Genetic Disorders
Andrew J. Pierce
Ouachita Baptist University
Cancer-related molecular mechanisms research
Disease Mechanisms Research
DNA Repair Mechanisms
LF Hutchins
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
Disease Mechanisms Research
Metabolism and Genetic Disorders
Clara M. Stiefel
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
Disease Mechanisms Research
DNA Repair Mechanisms
S. G. Lamb
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
Disease Mechanisms Research
Metabolism and Genetic Disorders
J.T. Pilkington
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
Disease Mechanisms Research
Metabolism and Genetic Disorders