Biography and Research Information
OverviewAI-generated summary
Baha’a Jabali's research focuses on the discovery and development of novel kinase inhibitors, particularly for cancer treatment. His work has led to the identification of compounds targeting specific pathways involved in tumor growth and proliferation. He has published research on macrocyclic kinase inhibitors, exploring strategies to limit conformational flexibility for improved targeting of the kinome.
Jabali's recent publications include the discovery of an orally active selective aurora kinase B inhibitor, N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide. He has also investigated pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors. His scholarship metrics include an h-index of 4, with 5 total publications and 104 total citations. Jabali collaborates with researchers at the University of Arkansas for Medical Sciences, including Brendan Frett and Baku Acharya.
Metrics
- h-index: 4
- Publications: 5
- Citations: 109
Selected Publications
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Discovery of N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide as the first orally active selective aurora kinase B inhibitor (2025)
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Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors (2024)
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Kinase inhibitor macrocycles: a perspective on limiting conformational flexibility when targeting the kinome with small molecules (2023)
Collaboration Network
Top Collaborators
Brendan Frett
University of Arkansas for Medical Sciences
3 shared publications
In database
- Kinase inhibitor macrocycles: a perspective on limiting conformational flexibility when targeting the kinome with small molecules
- Discovery of N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide as the first orally active selective aurora kinase B inhibitor
- Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors
Baku Acharya
University of Arkansas for Medical Sciences
2 shared publications
In database
- Kinase inhibitor macrocycles: a perspective on limiting conformational flexibility when targeting the kinome with small molecules
- Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors
Debasmita Saha
Discovery Institute (US)
2 shared publications
- Kinase inhibitor macrocycles: a perspective on limiting conformational flexibility when targeting the kinome with small molecules
- Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors
Daniel W. Armstrong
University of Arkansas for Medical Sciences
2 shared publications
In database
- Kinase inhibitor macrocycles: a perspective on limiting conformational flexibility when targeting the kinome with small molecules
- Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors
Maha Hanafi
Cairo University (EG)
2 shared publications
- Kinase inhibitor macrocycles: a perspective on limiting conformational flexibility when targeting the kinome with small molecules
- Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors
Alan Herrera-Rueda
University of Arkansas for Medical Sciences
1 shared publication
In database
- Kinase inhibitor macrocycles: a perspective on limiting conformational flexibility when targeting the kinome with small molecules
Naga Rajiv Lakkaniga
Indian Institute of Technology Dhanbad (IN)
1 shared publication
- Kinase inhibitor macrocycles: a perspective on limiting conformational flexibility when targeting the kinome with small molecules
Noemi Garcia Garcia
University of Arkansas for Medical Sciences
1 shared publication
In database
- Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors
Katie R. Ryan
University of Arkansas for Medical Sciences
1 shared publication
In database
- Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors
Phuc Tran
University of Arkansas for Medical Sciences
1 shared publication
In database
- Discovery of N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide as the first orally active selective aurora kinase B inhibitor
Marialuisa Moccia
University of Naples Federico II (IT)
1 shared publication
- Discovery of N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide as the first orally active selective aurora kinase B inhibitor
Xiuqi Wang
University of Arkansas for Medical Sciences
1 shared publication
In database
- Discovery of N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide as the first orally active selective aurora kinase B inhibitor
Annalisa Brescia
University of Naples Federico II (IT)
1 shared publication
- Discovery of N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide as the first orally active selective aurora kinase B inhibitor
Giorgia Federico
University of Naples Federico II (IT)
1 shared publication
- Discovery of N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide as the first orally active selective aurora kinase B inhibitor
Gunaganti Naresh
University of Arkansas for Medical Sciences
1 shared publication
In database
- Discovery of N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide as the first orally active selective aurora kinase B inhibitor
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