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Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
C
Cody Ashby
High Impact
Assistant Professor
Also affiliated: University of Arkansas Medical Center (2020–2023)
25 h-index
182 pubs
3,853 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Cody Ashby's research focuses on the molecular and genomic underpinnings of multiple myeloma and related B cell malignancies. His work investigates the evolutionary pathways from precursor stages to advanced disease, utilizing multi-omics approaches to understand alterations in the tumor microenvironment. Ashby has published research on the role of specific genetic and epigenetic factors in disease progression, including the impact of chromothripsis and TRIP13 modulation on tumor development.
His laboratory group also explores therapeutic strategies, with recent work examining the efficacy of bispecific CAR-T cells in controlling multiple myeloma growth. Additionally, Ashby's research has identified mechanisms by which certain factors, such as CST6, can suppress disease-related complications like osteolytic bone disease. He has a significant publication record, with an h-index of 25 and over 3,600 citations, and collaborates extensively with researchers at the University of Arkansas for Medical Sciences, including Fenghuang Zhan, John D. Shaughnessy, Carolina Schinke, and Sharmilan Thanendrarajan.
Metrics
- h-index: 25
- Publications: 182
- Citations: 3,853
Positions
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Assistant Professor 2014–presentUniversity of Arkansas for Medical Sciences Department of Biomedical Informatics Institutional directory
Selected Publications
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Rnd3 regulates lung cancer cell invasion and migration independently of ROCK1 signaling via alpha 5 integrin modulation (2026)
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Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Applying computational modelling to a high-risk multiple myeloma data set to create novel risk stratification groupings (2025)
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How Does Age at Diagnosis Influence Multiple Myeloma Survival? Empirical Evidence (2025)
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Equal survival for Black Americans with multiple myeloma when appropriately matched to White Americans (2025)
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The invisible divide: the impact of racial and geographic disparities on multiple myeloma outcomes - insights from a single-site study (2025)
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Prognostic impact of focal lesion location and persistence in multiple myeloma: insights from serial PET/DWI imaging (2025)
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Polyclonal plasma cell (PolyPC) signature as a key indicator for predicting the progression of MGUS to multiple myeloma (2025)
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Abstract 2645: Rnd3 depletion in lung cancer cell lines decreases cell invasion and migration in a ROCK1 independent manner (2025)
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Identification of Risk Factors for Myeloma Progression in African American Patients (2024)
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Single Nuclei Multiomic Profiling of Transcriptional and Chromatin Accessibility of Tumor Cells Underlines Extensive Cis-Regulatory Interaction during Multiple Myeloma Progression (2024)
Grants & Funding
As listed on this researcher's institutional profile.
- Contribution of osteocytes to the musculoskeletal effects of Multiple Myeloma NIH
- CD24 Tumor-initiating cell as a novel therapeutic target in myeloma US Department of Defense
- TRI KL2 Scholars award - Ashby UAMS College of Medicine
Collaboration Network
Top Collaborators
Gareth J. Morgan
New York University (US)
66 shared publications
- Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- Revealing the Impact of Structural Variants in Multiple Myeloma
Showing 5 of 66 shared publications
Brian A. Walker
Sylvester Comprehensive Cancer Center (US)
66 shared publications
- Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
- A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis
- Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma
Showing 5 of 66 shared publications
Carolina Schinke
University of Arkansas for Medical Sciences
61 shared publications
In database
- Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The level of deletion 17p and bi-allelic inactivation of TP53 has a significant impact on clinical outcome in multiple myeloma
Showing 5 of 61 shared publications
Frits van Rhee
Winthrop Rockefeller Foundation
60 shared publications
In database
- Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The level of deletion 17p and bi-allelic inactivation of TP53 has a significant impact on clinical outcome in multiple myeloma
Showing 5 of 60 shared publications
Michael Bauer
University of Arkansas for Medical Sciences
57 shared publications
In database
- Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
- A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis
- Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma
Showing 5 of 57 shared publications
Faith E. Davies
NYU Langone Health (US)
55 shared publications
- Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
- A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis
- Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma
Showing 5 of 55 shared publications
Maurizio Zangari
Winthrop Rockefeller Foundation
51 shared publications
In database
- Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The level of deletion 17p and bi-allelic inactivation of TP53 has a significant impact on clinical outcome in multiple myeloma
Showing 5 of 51 shared publications
Sharmilan Thanendrarajan
Winthrop Rockefeller Foundation
50 shared publications
In database
- Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The level of deletion 17p and bi-allelic inactivation of TP53 has a significant impact on clinical outcome in multiple myeloma
Showing 5 of 50 shared publications
Christopher P. Wardell
University of Arkansas Medical Center
43 shared publications
In database
- Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
- A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis
- Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
- Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
Showing 5 of 43 shared publications
Ruslana G. Tytarenko
University of Arkansas for Medical Sciences (US)
29 shared publications
- Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition?
Showing 5 of 29 shared publications
Eileen M. Boyle
NYU Langone Health (US)
27 shared publications
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- Revealing the Impact of Structural Variants in Multiple Myeloma
- Accelerated single cell seeding in relapsed multiple myeloma
- Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns
- Chromothripsis as a pathogenic driver of multiple myeloma
Showing 5 of 27 shared publications
Niels Weinhold
Heidelberg University (DE)
26 shared publications
- Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma
- Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly diagnosed patients
- The level of deletion 17p and bi-allelic inactivation of TP53 has a significant impact on clinical outcome in multiple myeloma
Showing 5 of 26 shared publications
Bart Barlogie
University of Arkansas for Medical Sciences
25 shared publications
In database
- Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The level of deletion 17p and bi-allelic inactivation of TP53 has a significant impact on clinical outcome in multiple myeloma
Showing 5 of 25 shared publications
Shayu Deshpande
University of Arkansas for Medical Sciences
22 shared publications
In database
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
- Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition?
- Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma
Showing 5 of 22 shared publications
Samer Al Hadidi
Winthrop Rockefeller Foundation
18 shared publications
In database
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- Concomitant deletion of the short arm (del(1p13.3)) and amplification or gain (1q21) of chromosome 1 by fluorescence in situ hybridization are associated with a poor clinical outcome in multiple myeloma
Showing 5 of 18 shared publications
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