David W. Ussery
Professor of Genetics
faculty
Research Areas
Biography and Research Information
OverviewAI-generated summary
David W. Ussery is a professor with a long-standing focus on the bioinformatic analysis of bacterial genomes, a field he has engaged with since the publication of the first bacterial genome sequence in 1995. His work has involved leading the Arkansas Center for Genomic Epidemiology and Medicine from 2016 to 2025. During his tenure, his group achieved significant milestones, including the sequencing of the first COVID-19 Omicron variant in Arkansas in December 2021 and the development of methods for pathogen monitoring in wastewater.
Ussery has also contributed to graduate education, teaching courses in the UAMS Department of BioMedical Informatics. He has extensive experience in disseminating knowledge globally, having conducted over 30 "Comparative Genomics" workshops across North and South America, Europe, Asia, and Africa. His research network includes collaborations with international groups in the UK, Denmark, Norway, Germany, and Belgium. Ussery's scholarship is marked by a high h-index of 62, with over 338 publications and more than 26,000 citations, including seven papers cited over a thousand times.
Metrics
- h-index: 62
- Publications: 336
- Citations: 26,207
Selected Publications
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A Randomized Double-Blind Placebo-Controlled Phase I/II Clinical Trial of a Human Papillomavirus Therapeutic Vaccine, PepCan, for Reducing Head and Neck Cancer Recurrence (2026)
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A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior (2025)
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Using machine learning to predict the severity of salmonella infection (2025)
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Abstract 1923: A tract of homozygosity analysis reveals methylation-driven <i>CSMD1</i> expression in non-small cell lung cancers (2025)
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A Randomized Double-Blind Phase 2 Clinical Trial Treating Cervical Intraepithelial Neoplasia 2/3 with PepCan or <i>Candida</i> (2025)
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Investigating the origins of the mutational signatures in cancer (2025)
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C.S. Lewis Philosopher — Who Changed My Life. Notes on the Margins of The Magician's Twin (2024)
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Review 1: "Emergence of Transmissible SARS-CoV-2 Variants with Decreased Sensitivity to Antivirals in Immunocompromised Patients with Persistent Infections" (2024)
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Reviews of "Emergence of Transmissible SARS-CoV-2 Variants with Decreased Sensitivity to Antivirals in Immunocompromised Patients with Persistent Infections" (2024)
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DNA structural features and variability of complete MHC locus sequences (2024)
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Immune responses in a phase 2 clinical trial of peptide-based therapeutic human papillomavirus vaccine, PepCan, versus <i>Candida</i> adjuvant alone in treating cervical intraepithelial neoplasia 2/3. (2024)
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Genomic surveillance of SARS-CoV-2 using long-range PCR primers (2024)
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Review of: "Can the definitions of SARS-Cov-2 and Covid-19 stand up to epistemological scrutiny?" (2023)
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Review of: "Evolution of new variants of SARS-CoV-2 during the pandemic: mutation-limited or selection-limited?" (2023)
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Genomic Surveillance of SARS-CoV-2 Using Long-Range PCR Primers (2023)
ARA Academy 2016 ARA Scholar
Collaboration Network
Top Collaborators
- Abstract 1923: A tract of homozygosity analysis reveals methylation-driven <i>CSMD1</i> expression in non-small cell lung cancers
- A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Supplementary Fig. S2 from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Data from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Supplementary Fig. S3 from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
Showing 5 of 15 shared publications
- Abstract 1923: A tract of homozygosity analysis reveals methylation-driven <i>CSMD1</i> expression in non-small cell lung cancers
- A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Supplementary Fig. S2 from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Data from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Supplementary Fig. S3 from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
Showing 5 of 15 shared publications
- Abstract 1923: A tract of homozygosity analysis reveals methylation-driven <i>CSMD1</i> expression in non-small cell lung cancers
- A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Supplementary Fig. S2 from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Data from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Supplementary Fig. S3 from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
Showing 5 of 15 shared publications
- Abstract 1923: A tract of homozygosity analysis reveals methylation-driven <i>CSMD1</i> expression in non-small cell lung cancers
- A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Supplementary Fig. S2 from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Data from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Supplementary Fig. S3 from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
Showing 5 of 15 shared publications
- Abstract 1923: A tract of homozygosity analysis reveals methylation-driven <i>CSMD1</i> expression in non-small cell lung cancers
- A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Supplementary Fig. S2 from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Data from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Supplementary Fig. S3 from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
Showing 5 of 15 shared publications
- A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Supplementary Fig. S2 from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Data from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Supplementary Fig. S3 from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
- Supplementary Fig. S4 from A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior
Showing 5 of 14 shared publications
- Two SARS-CoV-2 Genome Sequences of Isolates from Rural U.S. Patients Harboring the D614G Mutation, Obtained Using Nanopore Sequencing
- Investigating the origins of the mutational signatures in cancer
- Is amplification bias consequential in transposon sequencing (TnSeq) assays? A case study with a Staphylococcus aureus TnSeq library subjected to PCR-based and amplification-free enrichment methods
- A peptide-based human papillomavirus therapeutic vaccine, PepCan, or <i>Candida</i> adjuvant alone in treatment of cervical intraepithelial neoplasia 2/3 (CIN2/3).
- A Randomized Double-Blind Phase 2 Clinical Trial Treating Cervical Intraepithelial Neoplasia 2/3 with PepCan or <i>Candida</i>
Showing 5 of 7 shared publications
- Mash-based analyses of Escherichia coli genomes reveal 14 distinct phylogroups
- The first three waves of the Covid-19 pandemic hint at a limited genetic repertoire for SARS-CoV-2
- Comparison of Monkeypox virus genomes from the 2017 Nigeria outbreak and the 2022 outbreak
- Two SARS-CoV-2 Genome Sequences of Isolates from Rural U.S. Patients Harboring the D614G Mutation, Obtained Using Nanopore Sequencing
- DNA structural features and variability of complete MHC locus sequences
- Mash-based analyses of Escherichia coli genomes reveal 14 distinct phylogroups
- The first three waves of the Covid-19 pandemic hint at a limited genetic repertoire for SARS-CoV-2
- Comparison of Monkeypox virus genomes from the 2017 Nigeria outbreak and the 2022 outbreak
- DNA structural features and variability of complete MHC locus sequences
- Big data in genomic research for big questions with examples from covid-19 and other zoonoses
- A peptide-based human papillomavirus therapeutic vaccine, PepCan, or <i>Candida</i> adjuvant alone in treatment of cervical intraepithelial neoplasia 2/3 (CIN2/3).
- A Randomized Double-Blind Phase 2 Clinical Trial Treating Cervical Intraepithelial Neoplasia 2/3 with PepCan or <i>Candida</i>
- Immune responses in a phase 2 clinical trial of peptide-based therapeutic human papillomavirus vaccine, PepCan, versus <i>Candida</i> adjuvant alone in treating cervical intraepithelial neoplasia 2/3.
- A Randomized Double-Blind Placebo-Controlled Phase I/II Clinical Trial of a Human Papillomavirus Therapeutic Vaccine, PepCan, for Reducing Head and Neck Cancer Recurrence
- A peptide-based human papillomavirus therapeutic vaccine, PepCan, or <i>Candida</i> adjuvant alone in treatment of cervical intraepithelial neoplasia 2/3 (CIN2/3).
- A Randomized Double-Blind Phase 2 Clinical Trial Treating Cervical Intraepithelial Neoplasia 2/3 with PepCan or <i>Candida</i>
- Immune responses in a phase 2 clinical trial of peptide-based therapeutic human papillomavirus vaccine, PepCan, versus <i>Candida</i> adjuvant alone in treating cervical intraepithelial neoplasia 2/3.
- A Randomized Double-Blind Placebo-Controlled Phase I/II Clinical Trial of a Human Papillomavirus Therapeutic Vaccine, PepCan, for Reducing Head and Neck Cancer Recurrence
- A peptide-based human papillomavirus therapeutic vaccine, PepCan, or <i>Candida</i> adjuvant alone in treatment of cervical intraepithelial neoplasia 2/3 (CIN2/3).
- A Randomized Double-Blind Phase 2 Clinical Trial Treating Cervical Intraepithelial Neoplasia 2/3 with PepCan or <i>Candida</i>
- Immune responses in a phase 2 clinical trial of peptide-based therapeutic human papillomavirus vaccine, PepCan, versus <i>Candida</i> adjuvant alone in treating cervical intraepithelial neoplasia 2/3.
- A Randomized Double-Blind Placebo-Controlled Phase I/II Clinical Trial of a Human Papillomavirus Therapeutic Vaccine, PepCan, for Reducing Head and Neck Cancer Recurrence
- Mash-based analyses of Escherichia coli genomes reveal 14 distinct phylogroups
- A peptide-based human papillomavirus therapeutic vaccine, PepCan, or <i>Candida</i> adjuvant alone in treatment of cervical intraepithelial neoplasia 2/3 (CIN2/3).
- A Randomized Double-Blind Phase 2 Clinical Trial Treating Cervical Intraepithelial Neoplasia 2/3 with PepCan or <i>Candida</i>
- Genomic surveillance of SARS-CoV-2 using long-range PCR primers
- Genomic Surveillance of SARS-CoV-2 Using Long-Range PCR Primers
- Severe Acute Respiratory Syndrome Coronavirus-2 Lambda Variant Collected from a Child from Arkansas and Sequenced
- Genomic surveillance of SARS-CoV-2 using long-range PCR primers
- Genomic Surveillance of SARS-CoV-2 Using Long-Range PCR Primers
- Severe Acute Respiratory Syndrome Coronavirus-2 Lambda Variant Collected from a Child from Arkansas and Sequenced
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