David W. Ussery

◆ ARA Academy High Impact

Professor of Genetics

UAMS primary University of Arkansas

Also affiliated: Kunming University of Science and Technology (2018); Universitat de Miguel Hernández d'Elx (2012); Oklahoma State University (2026); Oak Ridge National Laboratory (2011–2017); Siriraj Hospital (2018); Norwegian Computing Center (2007); University of New Mexico (1984); Texas A&M University System (1992–1993); University of Oslo (2007–2011); Mahidol University (2018); University of Arkansas Medical Center (2017–2021); John Radcliffe Hospital (1994–1997); Moffitt Cancer Center (1994); University of Oxford (1994–1997); Molecular Microbiology and Genomics Consultants (Germany) (2017–2018); University of Applied Management Studies (2025); Oklahoma State University Oklahoma City (2025); Joint Institute for Computational Sciences (2014–2015); Anstalt für Verbrennungskraftmaschinen List (Austria) (2019); University of Cincinnati (1991); University of Tennessee at Knoxville (2014–2015); Texas A&M University (1996); University of Cincinnati Medical Center (1991); Technical University of Denmark (1999–2016)

Faculty Researcher

62 h-index 361 pubs 26,620 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website Research Group UAMS TRI Profile

OverviewAI-generated summary

David W. Ussery studies the bioinformatic analysis of bacterial genomes, a field he has engaged with since 1995. His research has focused on comparative genomics, including the investigation of Escherichia coli phylogroups and the genomic surveillance of pathogens like SARS-CoV-2 and Monkeypox virus. He led the Arkansas Center for Genomic Epidemiology and Medicine from 2016 to 2025, during which his group sequenced the first COVID-19 Omicron variant in Arkansas and developed methods for wastewater pathogen monitoring.

Ussery has experience teaching graduate courses in bioinformatics and has conducted numerous comparative genomics workshops globally. His scholarly work includes over 360 publications, with a significant number of highly cited papers, and an h-index of 62. He has established collaborative projects with researchers in several countries and maintains active lab operations. His work is supported by collaborations with colleagues at the University of Arkansas for Medical Sciences and the University of Arkansas at Little Rock.

His research interests also extend to areas such as the origins of mutational signatures in cancer and DNA structural features of MHC locus sequences. Ussery's contributions have been recognized with designations such as an ARA Academy member and a highly-impacted researcher.

Metrics

h-index: 62
Publications: 361
Citations: 26,620

Selected Publications

A Randomized Double-Blind Placebo-Controlled Phase I/II Clinical Trial of a Human Papillomavirus Therapeutic Vaccine, PepCan, for Reducing Head and Neck Cancer Recurrence (2026)

DOI OpenAlex
A Tracts of Homozygosity Approach Identifies Methylation-Regulated CSMD1 Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior (2025)

DOI OpenAlex
Using machine learning to predict the severity of salmonella infection (2025)

DOI OpenAlex
Abstract 1923: A tract of homozygosity analysis reveals methylation-driven CSMD1 expression in non-small cell lung cancers (2025)

DOI OpenAlex
A Randomized Double-Blind Phase 2 Clinical Trial Treating Cervical Intraepithelial Neoplasia 2/3 with PepCan or Candida (2025)

2 citations DOI OpenAlex
Investigating the origins of the mutational signatures in cancer (2025)

Nucleic Acids Research 18 citations DOI OpenAlex
C.S. Lewis Philosopher — Who Changed My Life. Notes on the Margins of The Magician's Twin (2024)

DOI OpenAlex
Review 1: "Emergence of Transmissible SARS-CoV-2 Variants with Decreased Sensitivity to Antivirals in Immunocompromised Patients with Persistent Infections" (2024)

DOI OpenAlex
Reviews of "Emergence of Transmissible SARS-CoV-2 Variants with Decreased Sensitivity to Antivirals in Immunocompromised Patients with Persistent Infections" (2024)

DOI OpenAlex
DNA structural features and variability of complete MHC locus sequences (2024)

Frontiers in Bioinformatics 7 citations DOI OpenAlex
Immune responses in a phase 2 clinical trial of peptide-based therapeutic human papillomavirus vaccine, PepCan, versus Candida adjuvant alone in treating cervical intraepithelial neoplasia 2/3. (2024)

1 citation DOI OpenAlex
Genomic surveillance of SARS-CoV-2 using long-range PCR primers (2024)

Frontiers in Microbiology 10 citations DOI OpenAlex
Review of: "Can the definitions of SARS-Cov-2 and Covid-19 stand up to epistemological scrutiny?" (2023)

DOI OpenAlex
Review of: "Evolution of new variants of SARS-CoV-2 during the pandemic: mutation-limited or selection-limited?" (2023)

DOI OpenAlex
Genomic Surveillance of SARS-CoV-2 Using Long-Range PCR Primers (2023)

1 citation DOI OpenAlex