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Institution-verified
Presence
Current · Arkansas
Last published
2026
Sources
Institutional record
Refreshed
2026-10-05
G
Gohar Azhar
Sourced from institutional research profiles (UAMS TRI or ARA).
High Impact
Professor
Also affiliated: Beth Israel Deaconess Medical Center (1996–2002); The University of Texas MD Anderson Cancer Center (2024); Harvard University (1996–2001); The University of Texas at San Antonio Health Science Center (2012); University of Arkansas Medical Center (2005–2025); Central Arkansas Veterans Healthcare System (2004–2019); Riddet Institute (2020); Politeknik Negeri Malang (2024–2025); Massey University (2020)
33 h-index
533 pubs
3,220 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Gohar Azhar's research has focused on the molecular and physiological mechanisms underlying cardiovascular aging and disease. Early work investigated oxidative stress pathways in cardiac muscle cells, exploring the role of c-Jun NH2-terminal kinase in DNA fragmentation and caspase activation. Further studies examined the effects of aging and gender on the autonomic control of blood pressure dynamics and cardiac morphology and function in senescent rats.
Azhar's group has also explored genetic and molecular factors influencing heart health. This includes research on the expression of microRNAs in the aging heart and the impact of serum response factor overexpression on cardiomyopathy in transgenic mice. Investigations into age-associated differences in the expression of Bcl-2 and Bax following coronary occlusion in adult rats have also been conducted.
With a highly cited researcher designation, Azhar has a significant publication record of 533 papers and over 3,200 citations, with an h-index of 33. Key collaborators include Jeanne Y. Wei, Pankaj Patyal, Ambika Verma, and Shakshi Sharma, all from the University of Arkansas for Medical Sciences, with whom Azhar has co-authored numerous publications. Azhar currently leads a research group and remains recently active.
Metrics
- h-index: 33
- Publications: 533
- Citations: 3,220
Positions
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Professor 2018–presentUniversity of Arkansas for Medical Sciences Department of Geriatrics ORCID
Selected Publications
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Biology of Aging I Antisense Oligonucleotide-Mediated SRF Reduction Ameliorates Mitochondrial Dysfunction in Cardiac Aging (2025)
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Dysregulation of SRF-Regulated Genes Accelerates the Development of Myocardial Aging (2025)
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Assessment of Caregiver Stress Across Dementia and Non-Dementia Groups (2025)
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Isoform-specific roles of SIRT2 in regulating mitochondrial gene expression (2025)
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P. gingivalis-LPS Activates the Alzheimer’s Disease-Associated Amyloid Secretase Pathway via Caspase-4 (2025)
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Opinions towards Aging in the Marshallese Community residing in Northwest Arkansas (2025)
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RETRACTED: Duloxetine, an SNRI, Targets pSTAT3 Signaling: In-Silico, RNA-Seq and In-Vitro Evidence for a Pleiotropic Mechanism of Pain Relief (2025)
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Mitochondrial Dynamics in Aging Heart (2025)
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Assessment of electrolyte abnormalities in older adults with COVID-19 and delirium (2025)
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Alternative Splicing of Serum Response Factor Reveals Isoform-Specific Remodeling in Cardiac Diseases (2025)
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Differential microRNA profiling of the Marshallese population in Arkansas reveals a higher association with chronic diseases (2025)
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Porphyromonas gingivalis-Lipopolysaccharide Induced Caspase-4 Dependent Noncanonical Inflammasome Activation Drives Alzheimer’s Disease Pathologies (2025)
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Cardiac-specific overexpression of serum response factor regulates age-associated decline in mitochondrial function (2025)
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KNOWLEDGE GAPS REGARDING NALOXONE USE AMONG OLDER ADULTS IN HIGH OPIOID PRESCRIBING REGIONS IN SOUTHERN USA (2024)
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DIFFERENTIAL EFFECT OF SIRT1 ON MITOCHONDRIAL FUNCTION: INSIGHTS INTO MITOCHONDRIAL RESPIRATORY COMPLEXES (2024)
Grants & Funding
As listed on this researcher's institutional profile.
- Arkansas Claude Pepper Older Americans Independence Center at UAMS NIH
- State Targeted Response (STR) No-Cost Extension AR Dept of Human Services/Division of Aging and Adult Services
- Consortium w/Essential: Nutritional Therapy in the Elderly with Heart Failure- Resubmission NIH/Nat. Inst. on Aging via Essential Blends, LLC
- Wolfe-FORTE: Effects of Fortetropin on Skeletal Muscle Protein Fractional Synthetic Rate in Older Men and Women MYOS RENS via University of California, Berkeley
- TCIA Sustainment and Scalability - Platforms for Quantitative Imaging Informatics in Precision Medicine NIH
- Phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy, safety, & tolerability of AVP-786 (deudextromethorphan hydrobromide/quinidine sulfate) for agitation treatment in patients w/ dementia of the Alzheimer's type Avanir Pharmaceuticals
- Advancing Health Disparities Research in Aging: The Aging Research in Criminal Justice & Health (ARCH) Network NIH
- Overcoming TWEAK Signaling to Restore Muscle and Mobility Function after Joint Replacement - Continuation - Continuation NIH/National Institutes of Health via University of Alabama at Birmingham
- Ferrando - D.E.B. Dairy - Effect of Dietary Protein Intake Distribution on Protein Metabolism and Skeletal Muscle National Dairy Council
- Ferrando - Dairy Macronutrient Effects on the Metabolic System The Dairy Research Institute
- Arkansas DHS State Opioid Response Grant Supplement SAMHSA
- Subcontract w/Essential Blends, LLC: UpBeat Phase 2 NIH/Nat. Inst. on Aging via Essential Blends, LLC
- PRagmatic EValuation of evENTS And Benefits of Lipid-lowering in oldEr adults (PREVENTABLE) (IRB 274254) NIH/Nat. Inst. on Aging via Duke University
- Transcription Regulation in the Aging Heart NIH
- DAABHS SOR III OPAL Narcan Drug Project Substance Abuse & Mental Health Services Administration via Arkansas Department of Human Services
- State Opioid Response Grant Substance Abuse & Mental Health Services Administration via Arkansas Department of Human Services
- Care Coordination and Home Telehealth Program for Older Adults with Cardiovascular Disease NIH/Nat. Inst. on Aging via Environment and Health Group, Inc.
Collaboration Network
Top Collaborators
Jeanne Y. Wei
University of Arkansas for Medical Sciences
77 shared publications
In database
- The Expression of microRNA and microRNA Clusters in the Aging Heart
- Hydration health literacy in the elderly
- Trends in Percutaneous Endoscopic Gastrostomy Placement in the Elderly From 1993 to 2003
- Exposure to High or Low Glucose Levels Accelerates the Appearance of Markers of Endothelial Cell Senescence and Induces Dysregulation of Nitric Oxide Synthase
- Valine improves mitochondrial function and protects against oxidative stress
Showing 5 of 77 shared publications
Xiaomin Zhang
Institute on Aging (US)
38 shared publications
- The Expression of microRNA and microRNA Clusters in the Aging Heart
- Exposure to High or Low Glucose Levels Accelerates the Appearance of Markers of Endothelial Cell Senescence and Induces Dysregulation of Nitric Oxide Synthase
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Identification of a Novel Serum Response Factor Cofactor in Cardiac Gene Regulation
Showing 5 of 38 shared publications
Pankaj Patyal
University of Arkansas for Medical Sciences
21 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
- Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function
Showing 5 of 21 shared publications
Ambika Verma
University of Arkansas for Medical Sciences
20 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
- Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function
Showing 5 of 20 shared publications
Robert R. Wolfe
Institute on Aging
19 shared publications
In database
- The anabolic response to a meal containing different amounts of protein is not limited by the maximal stimulation of protein synthesis in healthy young adults
- Protein intake distribution pattern does not affect anabolic response, lean body mass, muscle strength or function over 8 weeks in older adults: A randomized-controlled trial
- Acute ingestion of citrulline stimulates nitric oxide synthesis but does not increase blood flow in healthy young and older adults with heart failure
- Anabolic response to essential amino acid plus whey protein composition is greater than whey protein alone in young healthy adults
- Metabolic Evaluation of the Dietary Guidelines’ Ounce Equivalents of Protein Food Sources in Young Adults: A Randomized Controlled Trial
Showing 5 of 19 shared publications
Scott Schutzler
University of Arkansas for Medical Sciences
14 shared publications
In database
- The anabolic response to a meal containing different amounts of protein is not limited by the maximal stimulation of protein synthesis in healthy young adults
- Protein intake distribution pattern does not affect anabolic response, lean body mass, muscle strength or function over 8 weeks in older adults: A randomized-controlled trial
- Acute ingestion of citrulline stimulates nitric oxide synthesis but does not increase blood flow in healthy young and older adults with heart failure
- Anabolic response to essential amino acid plus whey protein composition is greater than whey protein alone in young healthy adults
- Metabolic Evaluation of the Dietary Guidelines’ Ounce Equivalents of Protein Food Sources in Young Adults: A Randomized Controlled Trial
Showing 5 of 14 shared publications
Shakshi Sharma
Institute on Aging
14 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Mitochondrial Dynamics in Aging Heart
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- L-VALINE TREATMENT IMPROVES CELLULAR MITOCHONDRIAL FUNCTION
Showing 5 of 14 shared publications
Arny A. Ferrando
Institute on Aging
13 shared publications
In database
- The anabolic response to a meal containing different amounts of protein is not limited by the maximal stimulation of protein synthesis in healthy young adults
- Protein intake distribution pattern does not affect anabolic response, lean body mass, muscle strength or function over 8 weeks in older adults: A randomized-controlled trial
- Anabolic response to essential amino acid plus whey protein composition is greater than whey protein alone in young healthy adults
- Metabolic Evaluation of the Dietary Guidelines’ Ounce Equivalents of Protein Food Sources in Young Adults: A Randomized Controlled Trial
- Quality of meal protein determines anabolic response in older adults
Showing 5 of 13 shared publications
Amanda Pangle
Institute on Aging
12 shared publications
In database
- Hydration health literacy in the elderly
- Feasibility of Conducting a 6-Months Long Home-based Exercise Program with Protein Supplementation in Elderly Community-dwelling Individuals with Heart Failure
- Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults
- Disparity and Multimorbidity in Heart Failure Patients Over the Age of 80
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
Showing 5 of 12 shared publications
Il‐Young Kim
University of Arkansas for Medical Sciences (US)
10 shared publications
- The anabolic response to a meal containing different amounts of protein is not limited by the maximal stimulation of protein synthesis in healthy young adults
- Protein intake distribution pattern does not affect anabolic response, lean body mass, muscle strength or function over 8 weeks in older adults: A randomized-controlled trial
- Acute ingestion of citrulline stimulates nitric oxide synthesis but does not increase blood flow in healthy young and older adults with heart failure
- Metabolic Evaluation of the Dietary Guidelines’ Ounce Equivalents of Protein Food Sources in Young Adults: A Randomized Controlled Trial
- Quality of meal protein determines anabolic response in older adults
Showing 5 of 10 shared publications
Steven C. Rogers
University of Arkansas for Medical Sciences (US)
7 shared publications
- Exposure to High or Low Glucose Levels Accelerates the Appearance of Markers of Endothelial Cell Senescence and Induces Dysregulation of Nitric Oxide Synthase
- Overexpression of p49/STRAP alters cellular cytoskeletal structure and gross anatomy in mice
- MicroRNA Clusters in the Adult Mouse Heart: Age-Associated Changes
- Does p49/STRAP, a SRF-binding protein (SRFBP1), modulate cardiac mitochondrial function in aging?
- Elevated oxygen consumption rate in response to acute low-glucose stress: Metformin restores rate to normal level
Showing 5 of 7 shared publications
Yingni Che
University of Arkansas for Medical Sciences
7 shared publications
In database
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Neutrophil Biomarkers Can Predict Cardiotoxicity of Anthracyclines in Breast Cancer
- Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
Showing 5 of 7 shared publications
Karen Coker
University of Arkansas for Medical Sciences
7 shared publications
In database
- Daily Consumption of a Specially Formulated Essential Amino Acid-Based Dietary Supplement Improves Physical Performance in Older Adults With Low Physical Functioning
- Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults
- Quality Improvement in Delirium Health Literacy in Older Adult Patients and Their Caregivers Attending a Geriatric Clinic
- Correction to: Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement versus whey protein in low physical functioning older adults
- KNOWLEDGE GAPS REGARDING NALOXONE USE AMONG OLDER ADULTS IN HIGH OPIOID PRESCRIBING REGIONS IN SOUTHERN USA
Showing 5 of 7 shared publications
Priya Mendiratta
University of Arkansas for Medical Sciences (US)
6 shared publications
- Trends in Percutaneous Endoscopic Gastrostomy Placement in the Elderly From 1993 to 2003
- Quality Improvement in Delirium Health Literacy in Older Adult Patients and Their Caregivers Attending a Geriatric Clinic
- Bariatric Procedures in Older Adults in the United States: Analysis of a Multicenter Database
- The PBAR Protocol: Antipsychotic Medication Reduction in the Nursing Home
- HEALTHCARE DISPARITY IN THE ASSESSMENT OF DEMENTIA IN THE PRIMARY CARE SETTING
Showing 5 of 6 shared publications
Fathima S. Ameer
Institute on Aging
6 shared publications
In database
- Alternative Splicing Increases Sirtuin Gene Family Diversity and Modulates Their Subcellular Localization and Function
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- Low Glucose Enhances the Cytoprotective Effect of Metformin Against Doxorubicin Induced Cytotoxicity in Normal Cells
- Sirtuin gene isoforms and genomic sequences of mouse and humans: Divergence across species
Showing 5 of 6 shared publications
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