Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-08
Ha‐Neui Kim
Federal Grant PI
High Impact
Associate Professor
Also affiliated: Seoul National University (2006–2023); University of Arkansas Medical Center (2021); Korea Institute of Oriental Medicine (2012); Central Arkansas Veterans Healthcare System (2013–2023); Seoul National University Dental Hospital (2008–2023)
Internal Med, College of Medicine
30 h-index
83 pubs
3,388 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Ha-Neui Kim's research focuses on the molecular mechanisms regulating bone homeostasis and disease. He studies osteoclast and osteoblast differentiation and function, investigating the roles of transcription factors and signaling pathways in bone remodeling. His work has explored the impact of FoxO proteins on osteoclastogenesis and bone resorption, as well as the involvement of Sirtuin1 in cortical bone formation.
Kim has received federal funding from the NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases for two projects. One, where he serves as Principal Investigator, investigates the role of mitochondrial quality control in bone homeostasis and disease. The other, where he is a Co-Principal Investigator, examines the antagonism of RANKL signaling by estrogen in osteoclasts. His research utilizes mouse models to study age-related changes in bone, such as intracortical bone remodeling and porosity, and the potential contribution of DNA damage and senescence in osteoprogenitors.
His scholarship metrics include an h-index of 30, with 83 total publications and 3,383 total citations. Kim collaborates with researchers at the University of Arkansas for Medical Sciences, including Maria Almeida, Aaron Warren, Stavros C. Manolagas, and Charles A. O’Brien.
Metrics
- h-index: 30
- Publications: 83
- Citations: 3,388
Positions
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Associate Professor publications 2013–2026University of Arkansas for Medical Sciences Internal Med, College of Medicine Institutional directory
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University of Arkansas for Medical Sciences publications 2013–2026ORCID
Selected Publications
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Targeting cellular senescence alleviates bone marrow aging (2026)
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Abstract LB220: Can dietary calcium prevent myeloma onset (2026)
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Deletion of the scavenger receptor Scarb1 in osteoblast progenitors and myeloid cells does not affect bone mass (2025)
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The Aging Landscape by scRNAseq of Mesenchymal Lineage Cells in Mouse Bone (2025)
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Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells (2025)
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Estrogens protect bone mass by inhibiting NAD + metabolism in osteoclasts (2025)
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Deletion of the scavenger receptor Scarb1 in osteoblast progenitors and myeloid cells does not affect bone mass (2025)
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Sirtuin-3 promotes osteoclast maturation and bone loss by regulating mitochondrial ROS production during ionizing radiation exposure (2025)
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Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells (2025)
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Oestradiol and osteoclast differentiation: Effects on p53 and mitochondrial metabolism (2024)
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Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone (2024)
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TMI-Based Dose-Escalated Bone Marrow Transplantation Can Help Preserve the Bone Marrow Microenvironment and Reduce Cellular Senescence in Old Mice (2023)
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A framework for defining mesenchymal cell types associated with murine periosteal and endosteal bone (2023)
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OR27-02 The Bone Anabolic Effect Of An Antibody Blocking Oxidized Phospholipids Is Associated With An Increase In Wnt10b In Osteoblasts. (2023)
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Peptidylarginine deiminase 2 plays a key role in osteogenesis by enhancing RUNX2 stability through citrullination (2023)
Federal Grants 2 $752,246 total
NIH
Co-PI
Mar 2024 - Feb 2029
NIH
Contact PI
Aug 2022 - Jul 2027
Role of Mitochondrial Quality Control in Bone Homeostasis and Disease
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- DNA damage in bone cells UAMS Intramural Grant Programs Principal Investigator
- Role of FoxOs in Skeletal Homeostasis- Resubmission - Continuation-Continuation - Continuation - Continuation NIH/Nat. Inst. of Arthritis & Musculoskeletal & Skin Diseases Co-Investigator
- Mechanisms of decreased bone formation with aging NIH/Nat. Inst. of Arthritis & Musculoskeletal & Skin Diseases Principal Investigator
- Role of Mitochondrial Deacetylase Sirt3 in Skeletal Homeostasis UAMS CMDR Principal Investigator
- Novel role of immunoproteaseome during renal cold storage and transplantation UAMS College of Medicine Principal Investigator
- Estrogen, Androgen, Aging and Bone Loss in Males VA Merit Co-Investigator
- DEAP Awards - H. Kim - UAMS VCRI - FY26 - Musculoskeletal Disintegration RESH Research Administration Principal Investigator
Collaboration Network
Top Collaborators
Maria Almeida
University of Arkansas for Medical Sciences
32 shared publications
In database
- FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation
- Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity
- Old age causes de novo intracortical bone remodeling and porosity in mice
- DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age
- Sirtuin1 (Sirt1) Promotes Cortical Bone Formation by Preventing β-Catenin Sequestration by FoxO Transcription Factors in Osteoblast Progenitors
Showing 5 of 32 shared publications
Charles A. O’Brien
Central Arkansas Veterans Healthcare System
19 shared publications
In database
- FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation
- Old age causes de novo intracortical bone remodeling and porosity in mice
- DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age
- Sirtuin1 (Sirt1) Promotes Cortical Bone Formation by Preventing β-Catenin Sequestration by FoxO Transcription Factors in Osteoblast Progenitors
- The Effects of Aging and Sex Steroid Deficiency on the Murine Skeleton Are Independent and Mechanistically Distinct
Showing 5 of 19 shared publications
Stavros C. Manolagas
University of Arkansas for Medical Sciences
17 shared publications
In database
- Old age causes de novo intracortical bone remodeling and porosity in mice
- DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age
- Sirtuin1 (Sirt1) Promotes Cortical Bone Formation by Preventing β-Catenin Sequestration by FoxO Transcription Factors in Osteoblast Progenitors
- The Effects of Aging and Sex Steroid Deficiency on the Murine Skeleton Are Independent and Mechanistically Distinct
- Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs
Showing 5 of 17 shared publications
Srividhya Iyer
University of Arkansas for Medical Sciences (US)
14 shared publications
- FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation
- DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age
- Sirtuin1 (Sirt1) Promotes Cortical Bone Formation by Preventing β-Catenin Sequestration by FoxO Transcription Factors in Osteoblast Progenitors
- The Effects of Aging and Sex Steroid Deficiency on the Murine Skeleton Are Independent and Mechanistically Distinct
- Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs
Showing 5 of 14 shared publications
Intawat Nookaew
University of Arkansas for Medical Sciences
12 shared publications
In database
- Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors
- Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone
- Piezo1 stimulates mitochondrial function via cAMP signaling
- The NAD salvage pathway in mesenchymal cells is indispensable for skeletal development in mice
- Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency
Showing 5 of 12 shared publications
Aaron Warren
University of Arkansas for Medical Sciences
10 shared publications
In database
- Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors
- A decrease in NAD+ contributes to the loss of osteoprogenitors and bone mass with aging
- The NAD salvage pathway in mesenchymal cells is indispensable for skeletal development in mice
- Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
Showing 5 of 10 shared publications
Robert L. Jilka
Central Arkansas Veterans Healthcare System
9 shared publications
In database
- FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation
- Old age causes de novo intracortical bone remodeling and porosity in mice
- DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age
- The Effects of Aging and Sex Steroid Deficiency on the Murine Skeleton Are Independent and Mechanistically Distinct
- Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors
Showing 5 of 9 shared publications
Elena Ambrogini
Central Arkansas Veterans Healthcare System
9 shared publications
In database
- FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation
- Increased marrow adipogenesis does not contribute to age‐dependent appendicular bone loss in female mice
- A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice
- RETRACTED: Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass
- Deletion of the Scavenger Receptor Scarb1 in Myeloid Cells Does Not Affect Bone Mass
Showing 5 of 9 shared publications
Horacio Gómez-Acevedo
University of Arkansas for Medical Sciences
9 shared publications
In database
- Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency
- A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice
- RETRACTED: Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass
- Mmp-13 deletion in cells of the mesenchymal lineage increases bone mass, decreases endocortical osteoclast number, and attenuates the cortical bone loss caused by estrogen deficiency in mice
- Mmp13 deletion in mesenchymal cells increases bone mass and attenuates the cortical bone loss caused by estrogen deficiency
Showing 5 of 9 shared publications
Li Han
University of Arkansas for Medical Sciences (US)
8 shared publications
- DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age
- Sirtuin1 (Sirt1) Promotes Cortical Bone Formation by Preventing β-Catenin Sequestration by FoxO Transcription Factors in Osteoblast Progenitors
- The Effects of Aging and Sex Steroid Deficiency on the Murine Skeleton Are Independent and Mechanistically Distinct
- Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs
- The Effects of Androgens on Murine Cortical Bone Do Not Require AR or ERα Signaling in Osteoblasts and Osteoclasts
Showing 5 of 8 shared publications
Daohong Zhou
The University of Texas at San Antonio Health Science Center (US)
8 shared publications
- Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity
- DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age
- Elimination of senescent osteoclast progenitors has no effect on the age‐associated loss of bone mass in mice
- Increased marrow adipogenesis does not contribute to age‐dependent appendicular bone loss in female mice
- Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice
Showing 5 of 8 shared publications
Michela Palmieri
Central Arkansas Veterans Healthcare System
7 shared publications
In database
- A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice
- RETRACTED: Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass
- Deletion of the Scavenger Receptor Scarb1 in Myeloid Cells Does Not Affect Bone Mass
- Retraction notice to “Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass” [Bone 170(2023) 116702]
- OR27-02 The Bone Anabolic Effect Of An Antibody Blocking Oxidized Phospholipids Is Associated With An Increase In Wnt10b In Osteoblasts.
Showing 5 of 7 shared publications
Filipa Ponte
University of Arkansas for Medical Sciences
6 shared publications
In database
- Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors
- A decrease in NAD+ contributes to the loss of osteoprogenitors and bone mass with aging
- Cxcl12 Deletion in Mesenchymal Cells Increases Bone Turnover and Attenuates the Loss of Cortical Bone Caused by Estrogen Deficiency in Mice
- Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency
- Mmp-13 deletion in cells of the mesenchymal lineage increases bone mass, decreases endocortical osteoclast number, and attenuates the cortical bone loss caused by estrogen deficiency in mice
Showing 5 of 6 shared publications
Adriana Lelis Carvalho
University of Arkansas for Medical Sciences
6 shared publications
In database
- Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors
- The role of reactive oxygen species in bone cell physiology and pathophysiology
- ECSIT is essential for RANKL-induced stimulation of mitochondria in osteoclasts and a target for the anti-osteoclastogenic effects of estrogens
- The NAD salvage pathway in mesenchymal cells is indispensable for skeletal development in mice
- Oestradiol and osteoclast differentiation: Effects on p53 and mitochondrial metabolism
Showing 5 of 6 shared publications
Qiang Fu
University of Arkansas for Medical Sciences
6 shared publications
In database
- Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone
- Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- Sirtuin-3 promotes osteoclast maturation and bone loss by regulating mitochondrial ROS production during ionizing radiation exposure
- A framework for defining mesenchymal cell types associated with murine periosteal and endosteal bone
Showing 5 of 6 shared publications
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