Ikjae Shin

Instructor

UAMS

Also affiliated: The University of Texas MD Anderson Cancer Center (2016); Seoul National University (2009); Winthrop Rockefeller Foundation (2020)

Faculty Researcher

Internal Med, College of Medicine

2 h-index 9 pubs 12 cited

Research Areas

Biomedical Subjects

Links

Research Group UAMS TRI Profile

OverviewAI-generated summary

Ikjae Shin's research focuses on developing and applying advanced molecular and genomic techniques to enhance precision medicine and drug development. His work involves microdissection methods, single-cell subtype analysis, and the integration of genomics and proteomics to analyze complex biological samples, particularly from rare tumor types. Shin has investigated the impact of antigen retrieval on genomic DNA from immunodissected samples and developed novel approaches for accuracy and reproducibility in genomic data science, such as NPARS.

His recent publications highlight advancements in proteogenomic analysis of histological sections for drug development and the application of reproducible genomic data science methods to rare tumor analysis. Shin collaborates with researchers at the University of Arkansas for Medical Sciences, including Donald J. Johann, Matthew A. Steliga, and Jason Muesse, with whom he has co-authored multiple publications. His work aims to improve the precision and efficiency of molecular diagnostics and therapeutic strategies.

Metrics

h-index: 2
Publications: 9
Citations: 12

Selected Publications

A Microdissection Protocol for Proteogenomic Analysis of Histological Sections to Advance Drug Development (2024)

Methods in molecular biology DOI OpenAlex
Advancing drug development by leveraging microdissection for proteogenomic analysis of histological sections. (2024)

Journal of Clinical Oncology DOI OpenAlex
Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention (2023)

Elsevier eBooks DOI OpenAlex
An advanced molecular medicine case report of a rare human tumor using genomics, pathomics, and radiomics (2023)

Frontiers in Genetics 6 citations DOI OpenAlex
Effect of Antigen Retrieval on Genomic DNA From Immunodissected Samples (2022)

Journal of Histochemistry & Cytochemistry 4 citations DOI OpenAlex
Abstract 5038: Applying reproducible genomic data science methods for the analysis of a rare tumor type (2022)

Cancer Research 1 citation DOI OpenAlex
Microdissection Methods Utilizing Single-Cell Subtype Analysis and the Impact on Precision Medicine (2022)

Methods in molecular biology 2 citations DOI OpenAlex
NPARS—A Novel Approach to Address Accuracy and Reproducibility in Genomic Data Science (2021)

Frontiers in Big Data 4 citations DOI OpenAlex
Synergizing microdissection with ddPCR to advance precision oncology. (2021)

Journal of Clinical Oncology 1 citation DOI OpenAlex
Utilizing single-cell-subtype analysis via advanced microdissection methods and the impact on precision medicine. (2020)

Journal of Clinical Oncology DOI OpenAlex
Visualizing collagen proteolysis by peptide hybridization: From 3D cell culture to in vivo imaging (2018)

Biomaterials 86 citations DOI OpenAlex
Liquid biopsy and its role in an advanced clinical trial for lung cancer (2018)

Experimental Biology and Medicine 51 citations DOI OpenAlex
Thymic PTH Increases After Thyroparathyroidectomy in C57BL/KaLwRij Mice (2018)

Endocrinology 6 citations DOI OpenAlex
Surgical thyroparathyroidectomy prevents progression of 5TGM1 murine multiple myeloma in vivo (2018)

Journal of bone oncology 4 citations DOI OpenAlex
Rigosertib, a Pan RAS Inhibitor, Decreases Mouse and Human Myeloma Cell Growth in Preclinical Models (2016)

Blood 1 citation DOI OpenAlex

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Grants & Funding

As listed on this researcher's institutional profile.

Scientific and methodological advancement in liquid biopsies to further the development of lung cancer-based precision medicine (Bio 3) U.S. Food and Drug Administration via Arkansas Research Alliance Co-Investigator