Jerry Ware
Professor
faculty
Physiology & Cell Biology, College of Medicine
Research Areas
Biography and Research Information
OverviewAI-generated summary
Jerry Ware, Professor in the Department of Physiology & Cell Biology at the University of Arkansas for Medical Sciences (UAMS) College of Medicine, investigates the role of platelets in various physiological and pathological processes. His research group has a significant focus on platelet function in chronic kidney disease (CKD), examining how platelets contribute to inflammation and dysregulation in patients with advanced stages of the condition. His work has explored therapeutic interventions, comparing the effects of antiplatelet agents like ticagrelor and clopidogrel on platelet aggregation and inflammatory markers in CKD patients.
Beyond CKD, Ware's research extends to the involvement of platelets in other conditions, including non-alcoholic steatohepatitis (NASH) and its potential link to liver cancer, as well as the role of platelet-neutrophil interactions in systemic sclerosis. He has utilized murine models, including transgenic and knockout mice, to study specific platelet glycoproteins, such as GPIb-IX, and their functions. Ware has received federal funding for his research, including a $693,302 grant from the NIH to study platelets in radiation-induced immune dysregulation.
With a distinguished academic career, Ware holds a h-index of 60 and has authored over 220 publications, accumulating more than 13,000 citations. He maintains collaborations with researchers at UAMS, including Nishank Jain, Adam Corken, Rupak Pathak, and Yasir Rahmatallah. His designation as a highly cited researcher underscores the impact of his contributions to the fields of physiology and cell biology.
Metrics
- h-index: 60
- Publications: 220
- Citations: 13,312
Selected Publications
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Identification and Characterization of Platelet Surface-membrane-derived Microparticles before and after Total-body Irradiation (2025)
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Contrasting Effects of Platelet GPVI Deletion Versus Syk Inhibition on Mouse Jugular Vein Puncture Wound Structure (2025)
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A GPVI-platelet-neutrophil-NET axis drives systemic sclerosis (2025)
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OC 10.3 Platelets Mediate Intracranial Aneurysm Formation and Rupture in Mice (2023)
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Platelet Count and Platelet Volume in Patients with CKD (2023)
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438 Platelets, Inflammation and Thrombosis in Chronic Kidney Disease (2023)
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Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease (2023)
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Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study (2022)
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Murine models of glycoprotein Ib-IX (2022)
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Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer (2022)
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Platelet glycoprotein Ibα provides radiation protection (2021)
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Role of Platelets in Chronic Kidney Disease (2021)
Federal Grants 2 $4,731,203 total
Grants & Funding
- Platelets in radiation-induced immune dysregulation NIH/Nat. Inst. of Allergy & Infectious Diseases Principal Investigator
- Leukocyte-platelet modulation of the systemic inflammatory response NIH Principal Investigator
- Transgenic analysis of platelet receptor expression NIH Principal Investigator
- Murine Hemostatic Properties of Thrombosomes DHHS - Biomedical Advanced Research and Development Authority - Pass Through: Cellphire, Inc. Principal Investigator
- In vivo, noninvasive, ultrasensitive photoacoustic detection of early breast cancer metastasis in bone US Department of the Army Principal Investigator
- Characterization and Analysis of Platelet Septins NIH Principal Investigator
- Murine Hemostatic Properties of Thrombosomes DHHS - Biomedical Advanced Research and Development Authority - Pass Through: Cellphire, Inc. Principal Investigator
- Platelet-leukocyte regulation of inflammatory responses- Resubmission- Resubmission American Heart Association Co-Investigator
Collaboration Network
Top Collaborators
- Role of Platelets in Chronic Kidney Disease
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease
- Platelet Count and Platelet Volume in Patients with CKD
- 438 Platelets, Inflammation and Thrombosis in Chronic Kidney Disease
Showing 5 of 6 shared publications
- Role of Platelets in Chronic Kidney Disease
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease
- Platelet Count and Platelet Volume in Patients with CKD
- 564 Platelets and Leukocytes Interact to Modulate Inflammation in Patients with CKD
- Role of Platelets in Chronic Kidney Disease
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease
- Platelet glycoprotein Ibα provides radiation protection
- Platelet glycoprotein Ibα provides radiation protection
- 564 Platelets and Leukocytes Interact to Modulate Inflammation in Patients with CKD
- Identification and Characterization of Platelet Surface-membrane-derived Microparticles before and after Total-body Irradiation
- Role of Platelets in Chronic Kidney Disease
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- 438 Platelets, Inflammation and Thrombosis in Chronic Kidney Disease
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease
- Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease
- Platelet Count and Platelet Volume in Patients with CKD
- Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease
- 438 Platelets, Inflammation and Thrombosis in Chronic Kidney Disease
- Platelet Count and Platelet Volume in Patients with CKD
- 564 Platelets and Leukocytes Interact to Modulate Inflammation in Patients with CKD
- Contrasting Effects of Platelet GPVI Deletion versus Syk Inhibition on Mouse Jugular Vein Puncture Wound Structure
- Contrasting Effects of Platelet GPVI Deletion Versus Syk Inhibition on Mouse Jugular Vein Puncture Wound Structure
- Contrasting Effects of Platelet GPVI Deletion versus Syk Inhibition on Mouse Jugular Vein Puncture Wound Structure
- Contrasting Effects of Platelet GPVI Deletion Versus Syk Inhibition on Mouse Jugular Vein Puncture Wound Structure
- Contrasting Effects of Platelet GPVI Deletion versus Syk Inhibition on Mouse Jugular Vein Puncture Wound Structure
- Contrasting Effects of Platelet GPVI Deletion Versus Syk Inhibition on Mouse Jugular Vein Puncture Wound Structure
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