Biography and Research Information
OverviewAI-generated summary
Kara A. O’Neal investigates host immune responses to malaria infection, specifically focusing on the role of T-lymphocytes and cytokines in the context of *Plasmodium yoelii* infection in mice. Her recent work has examined how the transcription factor Bhlhe40 influences the production of Interleukin-10 (IL-10) by CD4+ T cells during the early stages of infection. Additionally, her research has explored the requirement of ICOS (Inducible T-cell costimulator) expression for the maintenance, though not the formation, of germinal centers in the spleen following *P. yoelii* exposure. O'Neal collaborates with researchers at the University of Arkansas for Medical Sciences, including Jason S. Stumhofer and Camille L. Foscue, as well as Leah E. Latham from the National Center for Toxicological Research.
Metrics
- h-index: 2
- Publications: 3
- Citations: 8
Selected Publications
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Early enhanced control of <i>Plasmodium yoelii</i> infection in IL-10–deficient mice is independent of IFN-γ, IL-12, and the humoral response (2026)
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Bhlhe40 limits early IL-10 production from CD4 <sup>+</sup> T cells during <i>Plasmodium yoelii</i> 17X infection (2023)
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ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection (2022)
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ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection (2021)
Collaboration Network
Top Collaborators
Camille L. Foscue
University of Arkansas for Medical Sciences
3 shared publications
In database
- Bhlhe40 limits early IL-10 production from CD4 <sup>+</sup> T cells during <i>Plasmodium yoelii</i> 17X infection
- ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection
- ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection
Jason S. Stumhofer
University of Arkansas for Medical Sciences
3 shared publications
In database
- Bhlhe40 limits early IL-10 production from CD4 <sup>+</sup> T cells during <i>Plasmodium yoelii</i> 17X infection
- ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection
- ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection
Leah E. Latham
University of Arkansas for Medical Sciences
2 shared publications
In database
- ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection
- ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection
Enatha Ntirandekura
University of Arkansas for Medical Sciences
2 shared publications
In database
- ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection
- ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection
Sheldon L. Zeltner
University of Arkansas for Medical Sciences
1 shared publication
In database
- Bhlhe40 limits early IL-10 production from CD4 <sup>+</sup> T cells during <i>Plasmodium yoelii</i> 17X infection
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