Jason S. Stumhofer
Federal Grant PI
High Impact
Associate Professor
faculty
Microbiology & Immunology, College of Medicine
26 h-index
52 pubs
5,337 cited
Research Areas
Biography and Research Information
OverviewAI-generated summary
Jason S. Stumhofer's research focuses on the immune response to parasitic infections, particularly malaria. He investigates the cellular and molecular mechanisms that regulate the host's immune system during Plasmodium yoelii infection in mice. His work examines the roles of specific immune cells, such as B cells and T cells, and the cytokines they produce in controlling parasite burden and establishing long-term immunity.
Dr. Stumhofer has received federal funding from the National Institutes of Health/National Institute of Allergy and Infectious Diseases for two grants totaling over $261,000. These grants support his studies on the regulation of macrophage function during acute Plasmodium infection and the design of a B cell tetramer to track Plasmodium falciparum MSP2-specific B cells. His research group also investigates the role of intrinsic p53 activation in controlling germinal center B cell expansion during viral latency and the function of ICOS in germinal center maintenance.
With an h-index of 26 and over 5,299 citations across 52 publications, Dr. Stumhofer is recognized as a highly cited researcher. He collaborates with other researchers at the University of Arkansas for Medical Sciences, including Enatha Ntirandekura, Kara A. O’Neal, and Camille L. Foscue, on shared publications.
Metrics
- h-index: 26
- Publications: 52
- Citations: 5,337
Selected Publications
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Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment (2025)
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Bhlhe40 limits early IL-10 production from CD4 <sup>+</sup> T cells during <i>Plasmodium yoelii</i> 17X infection (2023)
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IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i> (2022)
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Towards rainbow portable Cytophone with laser diodes for global disease diagnostics (2022)
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ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection (2022)
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ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection (2021)
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IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i> (2021)
Federal Grants 2 $261,375 total
NIH/National Institute of Allergy and Infectious Diseases
Contact PI
Jun 2024 - Apr 2026
Regulation of macrophage function during acute infection with Plasmodium
NIH/National Institute of Allergy and Infectious Diseases
Contact PI
Nov 2021 - Oct 2023
Design of a B cell tetramer to track PfMSP2-specific B cells
Grants & Funding
- Regulation of macrophage function during acute infection with Plasmodium NIH/Nat. Inst. of Allergy & Infectious Diseases Principal Investigator
- Stumhofer Start up Account UAMS College of Medicine Principal Investigator
- A protective role for IL-17 in blood-stage malaria NIH Principal Investigator
- No FP attached UAMS College of Medicine Principal Investigator
- Multicolor Photoacoustic Malaria Detector NIH Co-Investigator
- Understanding the contribution of atypical B cell progenitors to the humoral response NIH Principal Investigator
- Design of a B cell tetramer to track PfMSP2-specific B cells NIH/Nat. Inst. of Allergy & Infectious Diseases Principal Investigator
- Regulation and function of B cells during malaria infection- Resubmission NIH Principal Investigator
Collaboration Network
Top Collaborators
Enatha Ntirandekura
University of Arkansas for Medical Sciences
4 shared publications
In database
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i>
- ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection
- IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i>
- ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection
Kara A. O’Neal
University of Arkansas for Medical Sciences
3 shared publications
In database
- Bhlhe40 limits early IL-10 production from CD4 <sup>+</sup> T cells during <i>Plasmodium yoelii</i> 17X infection
- ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection
- ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection
Camille L. Foscue
University of Arkansas for Medical Sciences
3 shared publications
In database
- Bhlhe40 limits early IL-10 production from CD4 <sup>+</sup> T cells during <i>Plasmodium yoelii</i> 17X infection
- ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection
- ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection
Susie L. Brown
University of Arkansas for Medical Sciences
2 shared publications
In database
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i>
- IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i>
Jonathan J. Bauer
University of Arkansas for Medical Sciences
2 shared publications
In database
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i>
- IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i>
Juhyung Lee
University of Arkansas for Medical Sciences
2 shared publications
In database
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i>
- IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i>
Leah E. Latham
University of Arkansas for Medical Sciences
2 shared publications
In database
- ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection
- ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection
Shana M. Owens
University of Arkansas for Medical Sciences
2 shared publications
In database
- Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment
- Intrinsic p53 Activation Restricts Gammaherpesvirus-Driven Germinal Center B Cell Expansion during Latency Establishment
Jeffrey M. Sifford
University of Arkansas for Medical Sciences
2 shared publications
In database
- Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment
- Intrinsic p53 Activation Restricts Gammaherpesvirus-Driven Germinal Center B Cell Expansion during Latency Establishment
Steven Murdock
University of Arkansas for Medical Sciences
2 shared publications
In database
- Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment
- Intrinsic p53 Activation Restricts Gammaherpesvirus-Driven Germinal Center B Cell Expansion during Latency Establishment
Eduardo Salinas
University of Arkansas for Medical Sciences
2 shared publications
In database
- Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment
- Intrinsic p53 Activation Restricts Gammaherpesvirus-Driven Germinal Center B Cell Expansion during Latency Establishment
Mark Manzano
University of Arkansas for Medical Sciences
2 shared publications
In database
- Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment
- Intrinsic p53 Activation Restricts Gammaherpesvirus-Driven Germinal Center B Cell Expansion during Latency Establishment
Debopam Ghosh
University of Arkansas for Medical Sciences
2 shared publications
In database
- Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment
- Intrinsic p53 Activation Restricts Gammaherpesvirus-Driven Germinal Center B Cell Expansion during Latency Establishment
J. Craig Forrest
University of Arkansas for Medical Sciences
2 shared publications
In database
- Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment
- Intrinsic p53 Activation Restricts Gammaherpesvirus-Driven Germinal Center B Cell Expansion during Latency Establishment
Hind J. Jawad
University of Arkansas for Medical Sciences (US)
1 shared publication
- Towards rainbow portable Cytophone with laser diodes for global disease diagnostics
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