Leah E. Latham Data-verified

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Researcher

NCTR

Last publication 2025 Last refreshed 2026-04-04

faculty

4 h-index 11 pubs 54 cited

Research Areas

Links

ORCID

OverviewAI-generated summary

Leah E. Latham's research program investigates the neurotoxicological effects of various substances and stresses on neural stem cells and developing brains. Her work includes the establishment of neural stem cell models from nonhuman primate brains for toxicity testing and the assessment of drugs like ketamine and fentanyl on neonatal brain development. Latham has also examined the potential neuroprotective effects of compounds such as carnitine and the impact of cannabidiol and its metabolites on human neural stem cells.

Her research extends to evaluating the effects of environmental stressors and anesthetics like desflurane on neural stem cell models. Additionally, Latham has explored the behavioral deficits and neurotoxicity associated with phencyclidine (PCP). She collaborates with researchers at the National Center for Toxicological Research, including Shuliang Liu, Tucker A. Patterson, William Slikker, and John Talpos, with whom she has co-authored multiple publications. Latham's work contributes to understanding the mechanisms of neurodevelopmental toxicity and identifying potential therapeutic interventions.

Metrics

h-index: 4
Publications: 11
Citations: 54

Selected Publications

Assessing the developmental effects of fentanyl and impacts on lipidomic profiling using neural stem cell models (2025)

2 citations DOI OpenAlex
The effects of cannabidiol and its main metabolites on human neural stem cells (2025)

4 citations DOI OpenAlex
Assessing potential desflurane-induced neurotoxicity using nonhuman primate neural stem cell models (2025)

2 citations DOI OpenAlex
Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing (2023)

3 citations DOI OpenAlex
Development of a primate model to evaluate the effects of ketamine and surgical stress on the neonatal brain (2023)

3 citations DOI OpenAlex
Phencyclidine (PCP)-induced neurotoxicity and behavioral deficits (2022)

DOI OpenAlex
ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection (2022)

3 citations DOI OpenAlex
ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection (2021)

DOI OpenAlex
Neuroprotective Effects of Carnitine and Its Potential Application to Ameliorate Neurotoxicity (2021)

18 citations DOI OpenAlex