Biography and Research Information
OverviewAI-generated summary
Researcher Lucy Fry investigates host-pathogen interactions, focusing on the cellular and molecular mechanisms of leishmaniasis. Her work examines how infections, specifically with *Leishmania major*, impact host cells like macrophages and endothelial cells. Fry's research has explored the role of hypoxia-inducible factors (HIF-α) in regulating macrophage inflammatory responses during murine leishmanial infections and how enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis. She also studies the transcriptional remodeling that occurs in macrophages in response to infection status and the inflammatory microenvironment. Fry has published 17 papers, with an h-index of 2, and collaborates with researchers including Hayden Roys and Anne K. Bowlin at the University of Arkansas for Medical Sciences.
Metrics
- h-index: 2
- Publications: 17
- Citations: 18
Selected Publications
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Guanylate-binding proteins balance iNOS/Arg-1 in myeloid cells during <i>L. major</i> infection and promote host defense to infection (2026)
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Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis 4267 (2025)
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From defense to disease: the multifaceted role of lymphatics during infection (2025)
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Guanylate-Binding Proteins Promote Host Defense Against <i>Leishmania major</i> by Balancing iNOS/Arg-1 in Myeloid Cells (2025)
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Dysregulated lymphatic remodeling promotes immunopathology during non-healing cutaneous leishmaniasis (2025)
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Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis (2025)
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HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection (2025)
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Host guanylate binding proteins participate in parasite control during Leishmania infection (2024)
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HIF-α signaling regulates the macrophage inflammatory response during <i>Leishmania major</i> infection (2024)
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Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs (2024)
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Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis (2024)
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Distinct lymphatic remodeling is associated with healing and non-healing murine cutaneous leishmaniasis (2023)
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HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection (2021)
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HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection (2021)
Collaboration Network
Top Collaborators
Tiffany Weinkopff
University of Arkansas for Medical Sciences
16 shared publications
In database
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
- Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis
Showing 5 of 16 shared publications
Hayden Roys
University of Arkansas for Medical Sciences
15 shared publications
In database
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
Showing 5 of 15 shared publications
Anne K. Bowlin
University of Arkansas for Medical Sciences
15 shared publications
In database
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
Showing 5 of 15 shared publications
Jordan T. Bird
University of Arkansas for Medical Sciences (US)
9 shared publications
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
- Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis
- HIF-α signaling regulates the macrophage inflammatory response during <i>Leishmania major</i> infection
Showing 5 of 9 shared publications
Gopinath Venugopal
University of Arkansas for Medical Sciences (US)
8 shared publications
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
Showing 5 of 8 shared publications
Charity L. Washam
University of Arkansas for Medical Sciences
7 shared publications
In database
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
- HIF-α signaling regulates the macrophage inflammatory response during <i>Leishmania major</i> infection
- Guanylate-Binding Proteins Promote Host Defense Against <i>Leishmania major</i> by Balancing iNOS/Arg-1 in Myeloid Cells
Showing 5 of 7 shared publications
Stephanie D. Byrum
Arkansas Children's Hospital
7 shared publications
In database
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
Showing 5 of 7 shared publications
Alexx Weaver
University of Arkansas for Medical Sciences
4 shared publications
In database
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis
- Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis 4267
Stephanie D. Byrum
3 shared publications
- Guanylate-Binding Proteins Promote Host Defense Against <i>Leishmania major</i> by Balancing iNOS/Arg-1 in Myeloid Cells
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis 4267
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection 4332
Manjunath Bettadapura
University of Arkansas for Medical Sciences
2 shared publications
In database
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
Steven Murdock
University of Arkansas for Medical Sciences
2 shared publications
In database
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
Humphrey Wanjala
University of Arkansas for Medical Sciences
2 shared publications
In database
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
Karl W. Boehme
University of Arkansas for Medical Sciences (US)
2 shared publications
- Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs
- From defense to disease: the multifaceted role of lymphatics during infection
Flavia Neto de Jesus
2 shared publications
- Dysregulated lymphatic remodeling promotes immunopathology during non-healing cutaneous leishmaniasis
- Impaired lymphatic remodeling leads to immunopathology during non-healing cutaneous leishmaniasis 4376
Matheus Batista Heitor Carneiro
2 shared publications
- Dysregulated lymphatic remodeling promotes immunopathology during non-healing cutaneous leishmaniasis
- Impaired lymphatic remodeling leads to immunopathology during non-healing cutaneous leishmaniasis 4376
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