Match tier Listed
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Lucy Fry

Researcher

Faculty Researcher

2 h-index 17 pubs 20 cited

  • Leishmaniasis, Cutaneous
  • Leishmania major
  • Animals
  • Macrophages
  • Mice
  • Female
  • Endothelial Cells
  • Humans
  • Leishmania
  • Disease Models, Animal
  • Mice, Inbred C57BL
  • Signal Transduction
  • Mice, Knockout
  • Hypoxia-Inducible Factor 1, alpha Subunit
  • Protein Biosynthesis

Biography and Research Information

OverviewAI-generated summary

Researcher Lucy Fry investigates host-pathogen interactions, focusing on the cellular and molecular mechanisms of leishmaniasis. Her work examines how infections, specifically with *Leishmania major*, impact host cells like macrophages and endothelial cells. Fry's research has explored the role of hypoxia-inducible factors (HIF-α) in regulating macrophage inflammatory responses during murine leishmanial infections and how enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis. She also studies the transcriptional remodeling that occurs in macrophages in response to infection status and the inflammatory microenvironment. Fry has published 17 papers, with an h-index of 2, and collaborates with researchers including Hayden Roys and Anne K. Bowlin at the University of Arkansas for Medical Sciences.

Metrics

  • h-index: 2
  • Publications: 17
  • Citations: 20

Selected Publications

  • Guanylate-binding proteins balance iNOS/Arg-1 in myeloid cells during <i>L. major</i> infection and promote host defense to infection (2026)
    mBio DOI OpenAlex
  • Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis 4267 (2025)
    The Journal of Immunology DOI OpenAlex
  • Impaired lymphatic remodeling leads to immunopathology during non-healing cutaneous leishmaniasis 4376 (2025)
    The Journal of Immunology DOI OpenAlex
  • From defense to disease: the multifaceted role of lymphatics during infection (2025)
    The Journal of Immunology DOI OpenAlex
  • Guanylate-Binding Proteins Promote Host Defense Against <i>Leishmania major</i> by Balancing iNOS/Arg-1 in Myeloid Cells (2025)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Dysregulated lymphatic remodeling promotes immunopathology during non-healing cutaneous leishmaniasis (2025)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis (2025)
    Lymphatic Research and Biology 1 citation DOI OpenAlex
  • HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection (2025)
    Frontiers in Immunology 2 citations DOI OpenAlex
  • Host guanylate binding proteins participate in parasite control during Leishmania infection (2024)
    The Journal of Immunology DOI OpenAlex
  • HIF-α signaling regulates the macrophage inflammatory response during <i>Leishmania major</i> infection (2024)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs (2024)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis (2024)
    bioRxiv (Cold Spring Harbor Laboratory) 2 citations DOI OpenAlex
  • Distinct lymphatic remodeling is associated with healing and non-healing murine cutaneous leishmaniasis (2023)
    The Journal of Immunology DOI OpenAlex
  • Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions (2023)
    Journal of Parasitology 3 citations DOI OpenAlex
  • HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection (2021)
    Pathogens 10 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

36 Collaborators 7 Institutions 3 Countries

Top Collaborators

View profile →
View profile →
View profile →
View profile →
View profile →
View profile →
View profile →
View profile →

Similar Researchers

Based on overlapping research topics