Landon B. Gatrell

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UAMS

Also affiliated: University of Arkansas Medical Center (2025)

2 h-index 4 pubs 25 cited

Research Areas

Biomedical Subjects

OverviewAI-generated summary

Landon B. Gatrell's research investigates cellular mechanisms related to aging, bone development, and tissue repair. His work has explored the role of the NAD salvage pathway in skeletal development in mice and the impact of mitochondrial oxidative stress and autophagy on bone mechanoresponsiveness in aging. Gatrell has also studied the effects of chemotherapy on bone mass and the contribution of cellular senescence to fibrotic repair in preclinical models. His publications include research on single-cell RNA sequencing of mesenchymal populations to identify pathways altered in age-associated osteoarthritis and the development of a transgenic rat model for assessing chondrogenesis <i>in vivo</i>. Gatrell collaborates with researchers at the University of Arkansas for Medical Sciences, including Aaron Warren and Maria Almeida.

Metrics

h-index: 2
Publications: 4
Citations: 25

Selected Publications

The Aging Landscape by scRNAseq of Mesenchymal Lineage Cells in Mouse Bone (2025)

Aging Cell 6 citations DOI OpenAlex
The adverse effects of chemotherapy on bone mass are not prevented by senolytics (2025)

Scientific Reports 1 citation DOI OpenAlex
Fibrocartilage repair involves chronic cellular senescence in a rat model of bone marrow stimulation (2025)

Osteoarthritis and Cartilage Open 1 citation DOI OpenAlex
Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness (2025)

Aging 4 citations DOI OpenAlex
Single cell RNA sequencing of mesenchymal populations from murine knees reveals distinct pathways altered in age-associated versus post-traumatic osteoarthritis (2024)

Osteoarthritis and Cartilage DOI OpenAlex
CHRONIC SENESCENCE CONTRIBUTES TO FIBROCARTILAGE REPAIR IN A PRECLINICAL MODEL OF BONE MARROW STIMULATION (2024)

Osteoarthritis and Cartilage DOI OpenAlex
The NAD salvage pathway in mesenchymal cells is indispensable for skeletal development in mice (2023)

Nature Communications 19 citations DOI OpenAlex
A Transgenic Rat for Noninvasive Assessment of Chondrogenesis in Vivo (2021)

Cartilage 3 citations DOI OpenAlex
Glucose effects on polyglutamine-induced proteotoxic stress in Caenorhabditis elegans (2019)

Biochemical and Biophysical Research Communications 28 citations DOI OpenAlex
Glucose availability impacts proteotoxic stress in Caenorhabditis elegans (2019)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex