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Biography and Research Information
OverviewAI-generated summary
Pilar Simmons' research investigates the physiological and cognitive effects of various medical treatments and environmental exposures in animal models. Her work has explored chemotherapy-induced cognitive impairment, examining the impact of drug combinations such as docetaxel, doxorubicin, and cyclophosphamide, as well as the potential neuroprotective role of piperlongumine. Simmons has also studied the effects of simulated galactic cosmic rays on bone health and cognitive performance in mice, with a focus on mitochondrial metabolism in osteoclasts and hippocampal-dependent cognitive function. Additional research areas include evaluating tocotrienols as an anti-breast cancer agent and the implications of gut microbiome changes following chemotherapy on depressive-like behavior. Simmons collaborates with several researchers at the University of Arkansas for Medical Sciences, including Taylor H. McElroy, Taurean Brown, Fabio Ntagwabira, and Christa Corley.
Metrics
- h-index: 7
- Publications: 14
- Citations: 144
Selected Publications
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The adverse effects of chemotherapy on bone mass are not prevented by senolytics (2025)
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The Impact of a UTI Pathway Bundle on Antibiotic Prescribing for Pediatric Urinary Tract Infections Through the Lens of Health Equity in Two Emergency Departments within a Children’s Hospital System (2024)
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A Bibliometric Analysis of Research Examining How Space Radiation Affects Human and Rodent Cognition, 1990–2023 (2024)
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Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior (2023)
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Evaluating the effects of low-dose simulated galactic cosmic rays on murine hippocampal-dependent cognitive performance (2022)
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Fractionated Proton Irradiation Does Not Impair Hippocampal-Dependent Short-Term or Spatial Memory in Female Mice (2022)
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Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment (2022)
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Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue (2021)
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Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue (2021)
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Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice (2021)
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Tocotrienols as an Anti-Breast Cancer Agent (2021)
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Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide (2021)
Collaboration Network
Top Collaborators
- Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide
- Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment
- Tocotrienols as an Anti-Breast Cancer Agent
- Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice
- Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior
Showing 5 of 11 shared publications
- Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide
- Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment
- Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior
- Evaluating the effects of low-dose simulated galactic cosmic rays on murine hippocampal-dependent cognitive performance
- Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue
Showing 5 of 8 shared publications
- Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment
- Tocotrienols as an Anti-Breast Cancer Agent
- Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior
- Evaluating the effects of low-dose simulated galactic cosmic rays on murine hippocampal-dependent cognitive performance
- Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue
Showing 5 of 6 shared publications
- Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide
- Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment
- Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue
- Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue
- Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide
- Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment
- Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue
- Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue
- Tocotrienols as an Anti-Breast Cancer Agent
- Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior
- Fractionated Proton Irradiation Does Not Impair Hippocampal-Dependent Short-Term or Spatial Memory in Female Mice
- Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide
- Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide
- Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide
- Tocotrienols as an Anti-Breast Cancer Agent
- Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice
- Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice
- Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice
- Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice
- Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice
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