Pilar Simmons

Researcher

University of Arkansas for Medical Sciences

faculty

7 h-index 14 pubs 138 cited

Research Areas

Dementia and Cognitive Impairment Research Cancer Treatment and Pharmacology Neuroscience and Neuropharmacology Research Bone health and treatments Gut microbiota and health Mitochondrial Function and Pathology Behavioral and Psychological Studies Pharmacological Effects and Toxicity Studies

Links

Research Group

Is this your profile? Verify and claim your profile

OverviewAI-generated summary

Pilar Simmons' research investigates the physiological and cognitive impacts of various medical treatments, particularly those related to chemotherapy and radiation. Simmons has published work examining cognitive impairment resulting from docetaxel, doxorubicin, and cyclophosphamide, as well as exploring piperlongumine as a potential neuro-protectant against such impairments. Other publications address the effects of simulated galactic cosmic rays on bone health and cognitive function in mice, and the role of tocotrienols as an anti-breast cancer agent. Further research includes the physiological and cognitive changes following cyclophosphamide, methotrexate, and fluorouracil treatments, with attention to the gut microbiome and depressive-like behaviors. Simmons' work also touches upon the effects of fractionated proton irradiation on memory in mice and methods for dissociating mouse brain hippocampal tissue.

Metrics

h-index: 7
Publications: 14
Citations: 138

Selected Publications

The adverse effects of chemotherapy on bone mass are not prevented by senolytics (2025) DOI
The Impact of a UTI Pathway Bundle on Antibiotic Prescribing for Pediatric Urinary Tract Infections Through the Lens of Health Equity in Two Emergency Departments within a Children’s Hospital System (2024) DOI
A Bibliometric Analysis of Research Examining How Space Radiation Affects Human and Rodent Cognition, 1990–2023 (2024) DOI
Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior (2023) DOI
Evaluating the effects of low-dose simulated galactic cosmic rays on murine hippocampal-dependent cognitive performance (2022) DOI
Fractionated Proton Irradiation Does Not Impair Hippocampal-Dependent Short-Term or Spatial Memory in Female Mice (2022) DOI
Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment (2022) DOI
Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue (2021) DOI
Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue (2021) DOI
Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice (2021) DOI
Tocotrienols as an Anti-Breast Cancer Agent (2021) DOI
Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide (2021) DOI