Pilar Simmons

Researcher

Last publication 2025 Last refreshed 2026-05-16

faculty

7 h-index 14 pubs 144 cited

Biography and Research Information

OverviewAI-generated summary

Pilar Simmons' research investigates the physiological and cognitive effects of various medical treatments and environmental exposures in animal models. Her work has explored chemotherapy-induced cognitive impairment, examining the impact of drug combinations such as docetaxel, doxorubicin, and cyclophosphamide, as well as the potential neuroprotective role of piperlongumine. Simmons has also studied the effects of simulated galactic cosmic rays on bone health and cognitive performance in mice, with a focus on mitochondrial metabolism in osteoclasts and hippocampal-dependent cognitive function. Additional research areas include evaluating tocotrienols as an anti-breast cancer agent and the implications of gut microbiome changes following chemotherapy on depressive-like behavior. Simmons collaborates with several researchers at the University of Arkansas for Medical Sciences, including Taylor H. McElroy, Taurean Brown, Fabio Ntagwabira, and Christa Corley.

Metrics

  • h-index: 7
  • Publications: 14
  • Citations: 144

Selected Publications

  • The adverse effects of chemotherapy on bone mass are not prevented by senolytics (2025)
  • The Impact of a UTI Pathway Bundle on Antibiotic Prescribing for Pediatric Urinary Tract Infections Through the Lens of Health Equity in Two Emergency Departments within a Children’s Hospital System (2024)
  • A Bibliometric Analysis of Research Examining How Space Radiation Affects Human and Rodent Cognition, 1990–2023 (2024)
  • Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior (2023)
    13 citations DOI OpenAlex
  • Evaluating the effects of low-dose simulated galactic cosmic rays on murine hippocampal-dependent cognitive performance (2022)
    7 citations DOI OpenAlex
  • Fractionated Proton Irradiation Does Not Impair Hippocampal-Dependent Short-Term or Spatial Memory in Female Mice (2022)
    3 citations DOI OpenAlex
  • Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment (2022)
    30 citations DOI OpenAlex
  • Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue (2021)
    2 citations DOI OpenAlex
  • Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue (2021)
    2 citations DOI OpenAlex
  • Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice (2021)
    16 citations DOI OpenAlex
  • Tocotrienols as an Anti-Breast Cancer Agent (2021)
    16 citations DOI OpenAlex
  • Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide (2021)
    31 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

31 Collaborators 6 Institutions 1 Country

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