Match tier Listed
Presence Current · Arkansas
Last published 2025
Sources OpenAlex · ORCID
Refreshed 2026-08-15

Pilar Simmons

Researcher

Faculty Researcher

7 h-index 14 pubs 140 cited

  • Animals
  • Mice
  • Female
  • Antineoplastic Combined Chemotherapy Protocols
  • Dioxolanes
  • Mice, Inbred C57BL
  • Piperidones
  • Cognitive Dysfunction
  • Docetaxel
  • Cyclophosphamide
  • Doxorubicin
  • Brain
  • Hippocampus
  • Senotherapeutics
  • Antineoplastic Agents

Biography and Research Information

OverviewAI-generated summary

Pilar Simmons' research investigates the physiological and cognitive effects of various medical treatments and environmental exposures in animal models. Her work has explored chemotherapy-induced cognitive impairment, examining the impact of drug combinations such as docetaxel, doxorubicin, and cyclophosphamide, as well as the potential neuroprotective role of piperlongumine. Simmons has also studied the effects of simulated galactic cosmic rays on bone health and cognitive performance in mice, with a focus on mitochondrial metabolism in osteoclasts and hippocampal-dependent cognitive function. Additional research areas include evaluating tocotrienols as an anti-breast cancer agent and the implications of gut microbiome changes following chemotherapy on depressive-like behavior. Simmons collaborates with several researchers at the University of Arkansas for Medical Sciences, including Taylor H. McElroy, Taurean Brown, Fabio Ntagwabira, and Christa Corley.

Metrics

  • h-index: 7
  • Publications: 14
  • Citations: 140

Selected Publications

  • The adverse effects of chemotherapy on bone mass are not prevented by senolytics (2025)
    Scientific Reports DOI OpenAlex
  • The Impact of a UTI Pathway Bundle on Antibiotic Prescribing for Pediatric Urinary Tract Infections Through the Lens of Health Equity in Two Emergency Departments within a Children’s Hospital System (2024)
    Journal of the Pediatric Infectious Diseases Society DOI OpenAlex
  • A Bibliometric Analysis of Research Examining How Space Radiation Affects Human and Rodent Cognition, 1990–2023 (2024)
    Radiation DOI OpenAlex
  • Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior (2023)
    Frontiers in Neuroscience 13 citations DOI OpenAlex
  • Evaluating the effects of low-dose simulated galactic cosmic rays on murine hippocampal-dependent cognitive performance (2022)
    Frontiers in Neuroscience 7 citations DOI OpenAlex
  • Fractionated Proton Irradiation Does Not Impair Hippocampal-Dependent Short-Term or Spatial Memory in Female Mice (2022)
    Toxics 3 citations DOI OpenAlex
  • Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment (2022)
    International Journal of Molecular Sciences 32 citations DOI OpenAlex
  • Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue (2021)
    Journal of Visualized Experiments 2 citations DOI OpenAlex
  • Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue (2021)
    Journal of Visualized Experiments 3 citations DOI OpenAlex
  • Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice (2021)
    International Journal of Molecular Sciences 17 citations DOI OpenAlex
  • Tocotrienols as an Anti-Breast Cancer Agent (2021)
    Antioxidants 16 citations DOI OpenAlex
  • Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide (2021)
    Brain Research 26 citations DOI OpenAlex
  • A Bibliometric Review of Artificial Extracellular Matrices Based on Tissue Engineering Technology Literature: 1990 through 2019 (2020)
    Materials 14 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

31 Collaborators 6 Institutions 1 Country

Top Collaborators

View profile →
View profile →
View profile →
View profile →
View profile →

Similar Researchers

Based on overlapping research topics