Linda L. Hardy
Vice-Chair for Research and Faculty Affairs
Also affiliated: University of Arkansas Medical Center (2015)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Linda Hardy investigates the role of RNA-binding proteins, specifically Musashi, in regulating gene expression within the pituitary gland. Her research focuses on how these proteins control the translation of messenger RNA (mRNA) in specific cell lineages, influencing pituitary function and cell fate determination. Recent publications demonstrate her work on how Musashi interacts with other protein complexes, such as LSM14B, to mediate translational activation of key pituitary mRNAs. Hardy's studies also examine the dynamic protein-protein interactions that regulate Musashi activity and its contribution to the specification and maintenance of distinct pituitary cell types. Her work has been supported by collaborations with researchers at the University of Arkansas for Medical Sciences, including Angus M. MacNicol and Gwen V. Childs, with whom she has co-authored multiple publications. Hardy's scholarly output includes 27 publications with 457 citations and an h-index of 11.
Metrics
- h-index: 11
- Publications: 25
- Citations: 344
Positions
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Vice-Chair for Research and Faculty Affairs publications 2009–2026University of Arkansas for Medical Sciences Institution web page
Selected Publications
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ELAVL1 and ELAVL4 Are Required for Musashi-Dependent Translational Activation (2026)
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ELAVL1 and ELAVL4 are required for Musashi-dependent translational activation (2026)
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SAT-016 Musashi Contributes to the Specification and Maintenance of Distinct Pituitary Cell Lineages. (2025)
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Musashi-dependent mRNA translational activation is mediated through association with the Scd6/Like-sm family member, LSM14B (2025)
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The Musashi RNA binding proteins direct the translational activation of key pituitary mRNAs (2024)
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FRI289 It Takes A Village: Musashi And Its Associated Proteins In The Adenohypophysis (2023)
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Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle (2023)
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The Cell Fate Determinant Musashi Is Controlled Through Dynamic Protein:Protein Interactions (2021)
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Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi (2020)
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Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators (2020)
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SAT-284 Musashi Exerts Translational Control Within Anterior Pituitary Cells of the POU1F1 Lineage (2020)
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SAT-406 Deletion of Musashi in Gonadotropes Leads to Increased GnRHR Protein Levels and Gonadotrope Dysfunction (2019)
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Association of Gnrhr mRNA With the Stem Cell Determinant Musashi: A Mechanism for Leptin-Mediated Modulation of GnRHR Expression (2017)
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Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2 (2017)
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Neural stem and progenitor cell fate transition requires regulation of Musashi1 function (2015)
Collaboration Network
Top Collaborators
- Enforcing temporal control of maternal mRNA translation during oocyte cell‐cycle progression
- Ringo/Cyclin-dependent Kinase and Mitogen-activated Protein Kinase Signaling Pathways Regulate the Activity of the Cell Fate Determinant Musashi to Promote Cell Cycle Re-entry in Xenopus Oocytes
- Association of Gnrhr mRNA With the Stem Cell Determinant Musashi: A Mechanism for Leptin-Mediated Modulation of GnRHR Expression
- Neural stem and progenitor cell fate transition requires regulation of Musashi1 function
- Efficient Translation of Dnmt1 Requires Cytoplasmic Polyadenylation and Musashi Binding Elements
Showing 5 of 19 shared publications
- Enforcing temporal control of maternal mRNA translation during oocyte cell‐cycle progression
- Ringo/Cyclin-dependent Kinase and Mitogen-activated Protein Kinase Signaling Pathways Regulate the Activity of the Cell Fate Determinant Musashi to Promote Cell Cycle Re-entry in Xenopus Oocytes
- Association of Gnrhr mRNA With the Stem Cell Determinant Musashi: A Mechanism for Leptin-Mediated Modulation of GnRHR Expression
- Neural stem and progenitor cell fate transition requires regulation of Musashi1 function
- Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2
Showing 5 of 16 shared publications
- Association of Gnrhr mRNA With the Stem Cell Determinant Musashi: A Mechanism for Leptin-Mediated Modulation of GnRHR Expression
- Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2
- Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi
- Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
Showing 5 of 13 shared publications
- Association of Gnrhr mRNA With the Stem Cell Determinant Musashi: A Mechanism for Leptin-Mediated Modulation of GnRHR Expression
- Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi
- Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- The Musashi RNA binding proteins direct the translational activation of key pituitary mRNAs
Showing 5 of 10 shared publications
- Association of Gnrhr mRNA With the Stem Cell Determinant Musashi: A Mechanism for Leptin-Mediated Modulation of GnRHR Expression
- Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- The Musashi RNA binding proteins direct the translational activation of key pituitary mRNAs
- SAT-406 Deletion of Musashi in Gonadotropes Leads to Increased GnRHR Protein Levels and Gonadotrope Dysfunction
Showing 5 of 6 shared publications
- Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- The Musashi RNA binding proteins direct the translational activation of key pituitary mRNAs
- Musashi-dependent mRNA translational activation is mediated through association with the Scd6/Like-sm family member, LSM14B
- SAT-284 Musashi Exerts Translational Control Within Anterior Pituitary Cells of the POU1F1 Lineage
Showing 5 of 6 shared publications
- Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- The Musashi RNA binding proteins direct the translational activation of key pituitary mRNAs
- Musashi-dependent mRNA translational activation is mediated through association with the Scd6/Like-sm family member, LSM14B
- SAT-284 Musashi Exerts Translational Control Within Anterior Pituitary Cells of the POU1F1 Lineage
Showing 5 of 6 shared publications
- Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi
- Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- The Musashi RNA binding proteins direct the translational activation of key pituitary mRNAs
- SAT-284 Musashi Exerts Translational Control Within Anterior Pituitary Cells of the POU1F1 Lineage
Showing 5 of 6 shared publications
- Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- The Musashi RNA binding proteins direct the translational activation of key pituitary mRNAs
- SAT-406 Deletion of Musashi in Gonadotropes Leads to Increased GnRHR Protein Levels and Gonadotrope Dysfunction
- SAT-284 Musashi Exerts Translational Control Within Anterior Pituitary Cells of the POU1F1 Lineage
- Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- SAT-284 Musashi Exerts Translational Control Within Anterior Pituitary Cells of the POU1F1 Lineage
- SAT-016 Musashi Contributes to the Specification and Maintenance of Distinct Pituitary Cell Lineages.
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Musashi-dependent mRNA translational activation is mediated through association with the Scd6/Like-sm family member, LSM14B
- The Cell Fate Determinant Musashi Is Controlled Through Dynamic Protein:Protein Interactions
- FRI289 It Takes A Village: Musashi And Its Associated Proteins In The Adenohypophysis
- Musashi-dependent mRNA translational activation is mediated through association with the Scd6/Like-sm family member, LSM14B
- SAT-016 Musashi Contributes to the Specification and Maintenance of Distinct Pituitary Cell Lineages.
- ELAVL1 and ELAVL4 are required for Musashi-dependent translational activation
- ELAVL1 and ELAVL4 Are Required for Musashi-Dependent Translational Activation
- Heck products of parthenolide and melampomagnolide-B as anticancer modulators that modify cell cycle progression
- ELAVL1 and ELAVL4 are required for Musashi-dependent translational activation
- ELAVL1 and ELAVL4 Are Required for Musashi-Dependent Translational Activation
- Ringo/Cyclin-dependent Kinase and Mitogen-activated Protein Kinase Signaling Pathways Regulate the Activity of the Cell Fate Determinant Musashi to Promote Cell Cycle Re-entry in Xenopus Oocytes
- Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2
- Heck products of parthenolide and melampomagnolide-B as anticancer modulators that modify cell cycle progression
- Enforcing temporal control of maternal mRNA translation during oocyte cell‐cycle progression
- Ringo/Cyclin-dependent Kinase and Mitogen-activated Protein Kinase Signaling Pathways Regulate the Activity of the Cell Fate Determinant Musashi to Promote Cell Cycle Re-entry in Xenopus Oocytes
- Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2
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