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Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-20
Angela K. Odle profile photo

Angela K. Odle

Federal Grant PI

Assistant Professor

Also affiliated: Instituto de Neurociencias (2023); Arkansas Department of Agriculture (2024)

Faculty Researcher

Neurobiology & Developmental Science, College of Medicine

17 h-index 73 pubs 1,203 cited

  • Animals
  • Mice
  • Female
  • Male
  • Leptin
  • Pituitary Gland
  • Somatotrophs
  • Receptors, Leptin
  • Obesity
  • Diet, High-Fat
  • Humans
  • Gene Expression Regulation
  • Mice, Inbred C57BL
  • Growth Hormone
  • Signal Transduction

Biography and Research Information

OverviewAI-generated summary

Angela K. Odle's research investigates the molecular mechanisms underlying metabolic adaptation and reproductive function, with a focus on the influence of diet and oxidative stress on the pituitary gland. Her work explores how factors such as high-fat diets impact gene expression and cell metabolism within the anterior pituitary. Odle also studies the role of specific RNA-binding proteins, like Musashi, in controlling mRNA translation and their contribution to reproductive cycles. Her research extends to the effects of leptin receptor signaling on somatotrope transcriptome maturation and the potential for maternal nutrition to influence offspring's metabolic resilience.

Her federally funded research, supported by a $443,348 grant from the NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, focuses on paracrine and endocrine influences on gonadotrope development and function. Odle leads a research group and has a publication record including work on adipo-glial signaling in peripheral nerve regeneration and chemotherapy-induced oxidative stress in the ovary. Her scholarship metrics include an h-index of 17 and over 1,100 citations.

Metrics

  • h-index: 17
  • Publications: 73
  • Citations: 1,203

Selected Publications

  • ELAVL1 and ELAVL4 Are Required for Musashi-Dependent Translational Activation (2026)
    Biomolecules DOI OpenAlex
  • ELAVL1 and ELAVL4 are required for Musashi-dependent translational activation (2026)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Gonadotrope remodeling in sustained low estrogen states: single-cell transcriptomic analysis reveals gonadotrope subtypes and activation of stem cell populations (2026)
    Biology of Reproduction 1 citation DOI OpenAlex
  • Secretogranin II–derived peptide secretoneurin differentially stimulates luteinizing hormone secretion by age and sex in ex vivo murine pituitaries (2026)
    Biology of Reproduction DOI OpenAlex
  • OR13-08 Secretoneurin Modulates Gonadotrope Function Cyclically to Regulate LH Secretion (2025)
    Journal of the Endocrine Society DOI OpenAlex
  • SAT-001 Impact of VCD-induced Menopause on Gonadotrope Transcriptomics Reveals Estrogen-dependent Genes in the GnRH Signaling Pathway (2025)
    Journal of the Endocrine Society DOI OpenAlex
  • SAT-016 Musashi Contributes to the Specification and Maintenance of Distinct Pituitary Cell Lineages. (2025)
    Journal of the Endocrine Society DOI OpenAlex
  • High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes (2025)
    Frontiers in Endocrinology 1 citation DOI OpenAlex
  • Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice (2025)
    Endocrinology 5 citations DOI OpenAlex
  • Solving the Mystery of the Neonatal GH Surge (2024)
    Endocrinology DOI OpenAlex
  • 8572 A 30% Maternal Caloric Restriction Alters Expression of Musashi Targets in the Neonatal and Adult Pituitary Proteomes of FVB Mice (2024)
    Journal of the Endocrine Society DOI OpenAlex
  • 8649 Ablation of Leptin Receptors in Somatotropes Impacts Transcriptomic Plasticity in the Pou1f1 Lineage of Female Pituitary Cells (2024)
    Journal of the Endocrine Society DOI OpenAlex
  • The Musashi RNA binding proteins direct the translational activation of key pituitary mRNAs (2024)
    Scientific Reports 8 citations DOI OpenAlex
  • Maternal undernutrition results in transcript changes in male offspring that may promote resistance to high fat diet induced weight gain (2024)
    Frontiers in Endocrinology 4 citations DOI OpenAlex
  • Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism (2023)
    Endocrinology 12 citations DOI OpenAlex

View all publications on OpenAlex →

Federal Grants 1 $443,348 total

NIH Contact PI Jul 2026 - Apr 2031

Paracrine and Endocrine Influences on Gonadotrope Development and Function

Eunice Kennedy Shriver National Institute of Child Health and Human Development $443,348 R01

Grants & Funding

As listed on this researcher's institutional profile. Federal awards with verified records are shown above.

  • Enhancement Project to Improve Access to Food Services and Mental Well-Being Administration for Community Living Principal Investigator
  • The Impact of Obesity on Somatotrope Function NIH Co-Investigator
  • Post-transcriptional Pathways that Signal Leptin Regulation of Gonadotropes NIH Co-Investigator
  • The Significance of Leptin Signals to Neonatal Somatotropes and Gonadotropes NIH Co-Investigator
  • Molecular mechanisms of pituitary plasticity NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases Co-Investigator

Collaboration Network

40 Collaborators 11 Institutions 3 Countries

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