P
Paul D. Adams Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
High Impact
Professor
faculty
99 h-index
577 pubs
134,611 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Paul D. Adams' research focuses on the development and application of computational methods for understanding biological structures, particularly proteins. His work has contributed to advancements in predicting protein structures and interactions, utilizing approaches such as neural networks. Adams has investigated the utility of tools like AlphaFold, evaluating their role in accelerating experimental structure determination and as hypothesis-generating tools. His research also extends to the validation of structural models derived from techniques like cryo-electron microscopy and the development of foundational semantic tools for structural biology data management.
With a distinguished publication record, including 577 publications and over 134,000 citations, Adams is recognized as a highly cited researcher. His scholarship metrics, including an h-index of 99, underscore his significant contributions to the field. His collaborations include work with researchers at the University of Arkansas at Fayetteville and the University of Arkansas at Monticello, demonstrating a network of scientific exchange. Adams leads an active research group and maintains an updated laboratory website, indicating ongoing research activities.
Metrics
- h-index: 99
- Publications: 577
- Citations: 134,611
Selected Publications
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Fibroblast Growth Factors: Roles and Emerging Therapeutic Applications (2025)
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Board 198: An Innovation-Themed National Science Foundation S-STEM Grant Program (2024)
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Board 312: Increasing Retention for Rural and Underrepresented STEM Students (2024)
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Board 302: Helping Rural and Underrepresented Students Succeed in STEM (2024)
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A Simple Purification Method for Heat-Stable Recombinant Low Molecular Weight Proteins and Peptides Via GST-Fusion Products (2023)
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Targeting K-Ras Mutations Show Promise Towards Ending Ras’s“Undruggable” Era (2022)
Collaboration Network
Top Collaborators
J.H. Pereira
Lawrence Berkeley National Laboratory (US)
11 shared publications
- Accurate prediction of protein structures and interactions using a three-track neural network
- Complete integration of carbene-transfer chemistry into biosynthesis
- Efficient production of oxidized terpenoids via engineering fusion proteins of terpene synthase and cytochrome P450
- Accurate prediction of protein structures and interactions using a 3-track network
- Structural plasticity enables evolution and innovation of RuBisCO assemblies
Showing 5 of 11 shared publications
Nigel W. Moriarty
Lawrence Berkeley National Laboratory (US)
11 shared publications
- Structural dynamics in the water and proton channels of photosystem II during the S2 to S3 transition
- PDBx/mmCIF Ecosystem: Foundational Semantic Tools for Structural Biology
- Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2
- Macromolecular refinement of X-ray and cryoelectron microscopy structures with Phenix/OPLS3e for improved structure and ligand quality
- <i>In situ</i> ligand restraints from quantum-mechanical methods
Showing 5 of 11 shared publications
Pavel V. Afonine
Lawrence Berkeley National Laboratory (US)
10 shared publications
- AlphaFold predictions are valuable hypotheses and accelerate but do not replace experimental structure determination
- Improved AlphaFold modeling with implicit experimental information
- Cryo-EM model validation recommendations based on outcomes of the 2019 EMDataResource challenge
- Accelerating crystal structure determination with iterative <i>AlphaFold</i> prediction
- AlphaFold predictions are valuable hypotheses, and accelerate but do not replace experimental structure determination
Showing 5 of 10 shared publications
Trent R. Northen
Lawrence Berkeley National Laboratory (US)
9 shared publications
- Complete integration of carbene-transfer chemistry into biosynthesis
- Alkaline-SDS cell lysis of microbes with acetone protein precipitation for proteomic sample preparation in 96-well plate format
- Expanding Extender Substrate Selection for Unnatural Polyketide Biosynthesis by Acyltransferase Domain Exchange within a Modular Polyketide Synthase
- Experimental and theoretical insights into the effects of pH on catalysis of bond-cleavage by the lignin peroxidase isozyme H8 from Phanerochaete chrysosporium
- Low-abundance populations distinguish microbiome performance in plant cell wall deconstruction
Showing 5 of 9 shared publications
Christopher J. Petzold
Lawrence Berkeley National Laboratory (US)
9 shared publications
- Complete integration of carbene-transfer chemistry into biosynthesis
- Genome-scale and pathway engineering for the sustainable aviation fuel precursor isoprenol production in Pseudomonas putida
- Alkaline-SDS cell lysis of microbes with acetone protein precipitation for proteomic sample preparation in 96-well plate format
- Expanding Extender Substrate Selection for Unnatural Polyketide Biosynthesis by Acyltransferase Domain Exchange within a Modular Polyketide Synthase
- Simultaneous carbon catabolite repression governs sugar and aromatic co-utilization in <i>Pseudomonas putida</i> M2
Showing 5 of 9 shared publications
Billy K. Poon
Lawrence Berkeley National Laboratory (US)
9 shared publications
- AlphaFold predictions are valuable hypotheses and accelerate but do not replace experimental structure determination
- Improved AlphaFold modeling with implicit experimental information
- Accelerating crystal structure determination with iterative <i>AlphaFold</i> prediction
- AlphaFold predictions are valuable hypotheses, and accelerate but do not replace experimental structure determination
- Improved AlphaFold modeling with implicit experimental information
Showing 5 of 9 shared publications
Blake A. Simmons
Lawrence Berkeley National Laboratory (US)
8 shared publications
- Engineering Saccharomyces cerevisiae for isoprenol production
- Genome-scale and pathway engineering for the sustainable aviation fuel precursor isoprenol production in Pseudomonas putida
- Experimental and theoretical insights into the effects of pH on catalysis of bond-cleavage by the lignin peroxidase isozyme H8 from Phanerochaete chrysosporium
- Low-abundance populations distinguish microbiome performance in plant cell wall deconstruction
- Simultaneous carbon catabolite repression governs sugar and aromatic co-utilization in <i>Pseudomonas putida</i> M2
Showing 5 of 8 shared publications
Kai Deng
Sandia National Laboratories California (US)
8 shared publications
- Complete integration of carbene-transfer chemistry into biosynthesis
- Expanding Extender Substrate Selection for Unnatural Polyketide Biosynthesis by Acyltransferase Domain Exchange within a Modular Polyketide Synthase
- Experimental and theoretical insights into the effects of pH on catalysis of bond-cleavage by the lignin peroxidase isozyme H8 from Phanerochaete chrysosporium
- Low-abundance populations distinguish microbiome performance in plant cell wall deconstruction
- A multiplexed nanostructure-initiator mass spectrometry (NIMS) assay for simultaneously detecting glycosyl hydrolase and lignin modifying enzyme activities
Showing 5 of 8 shared publications
Yan Chen
Lawrence Berkeley National Laboratory (US)
8 shared publications
- Complete integration of carbene-transfer chemistry into biosynthesis
- Genome-scale and pathway engineering for the sustainable aviation fuel precursor isoprenol production in Pseudomonas putida
- Alkaline-SDS cell lysis of microbes with acetone protein precipitation for proteomic sample preparation in 96-well plate format
- Expanding Extender Substrate Selection for Unnatural Polyketide Biosynthesis by Acyltransferase Domain Exchange within a Modular Polyketide Synthase
- A multiplexed nanostructure-initiator mass spectrometry (NIMS) assay for simultaneously detecting glycosyl hydrolase and lignin modifying enzyme activities
Showing 5 of 8 shared publications
Jennifer Gin
Lawrence Berkeley National Laboratory (US)
8 shared publications
- Genome-scale and pathway engineering for the sustainable aviation fuel precursor isoprenol production in Pseudomonas putida
- Alkaline-SDS cell lysis of microbes with acetone protein precipitation for proteomic sample preparation in 96-well plate format
- Expanding Extender Substrate Selection for Unnatural Polyketide Biosynthesis by Acyltransferase Domain Exchange within a Modular Polyketide Synthase
- Simultaneous carbon catabolite repression governs sugar and aromatic co-utilization in <i>Pseudomonas putida</i> M2
- A multiplexed nanostructure-initiator mass spectrometry (NIMS) assay for simultaneously detecting glycosyl hydrolase and lignin modifying enzyme activities
Showing 5 of 8 shared publications
Aindrila Mukhopadhyay
Lawrence Berkeley National Laboratory (US)
7 shared publications
- Engineering Saccharomyces cerevisiae for isoprenol production
- Complete integration of carbene-transfer chemistry into biosynthesis
- Efficient production of oxidized terpenoids via engineering fusion proteins of terpene synthase and cytochrome P450
- Genome-scale and pathway engineering for the sustainable aviation fuel precursor isoprenol production in Pseudomonas putida
- Scalable and automated CRISPR-based strain engineering using droplet microfluidics
Showing 5 of 7 shared publications
Thomas C. Terwilliger
Los Alamos National Laboratory (US)
7 shared publications
- AlphaFold predictions are valuable hypotheses and accelerate but do not replace experimental structure determination
- Improved AlphaFold modeling with implicit experimental information
- Accelerating crystal structure determination with iterative <i>AlphaFold</i> prediction
- AlphaFold predictions are valuable hypotheses, and accelerate but do not replace experimental structure determination
- Improved AlphaFold modeling with implicit experimental information
Showing 5 of 7 shared publications
Tristan I. Croll
University of Cambridge (GB)
6 shared publications
- AlphaFold predictions are valuable hypotheses and accelerate but do not replace experimental structure determination
- Improved AlphaFold modeling with implicit experimental information
- Accelerating crystal structure determination with iterative <i>AlphaFold</i> prediction
- AlphaFold predictions are valuable hypotheses, and accelerate but do not replace experimental structure determination
- Community recommendations on cryoEM data archiving and validation
Showing 5 of 6 shared publications
Jay D. Keasling
University of California, Berkeley (US)
6 shared publications
- Complete integration of carbene-transfer chemistry into biosynthesis
- Expanding Extender Substrate Selection for Unnatural Polyketide Biosynthesis by Acyltransferase Domain Exchange within a Modular Polyketide Synthase
- Automated Platform for the Plasmid Construction Process
- Systematic engineering for production of anti-aging sunscreen compound in Pseudomonas putida
- A polyketide-based biosynthetic platform for diols, amino alcohols and hydroxy acids
Showing 5 of 6 shared publications
Edward E. K. Baidoo
Lawrence Berkeley National Laboratory (US)
5 shared publications
- Engineering Saccharomyces cerevisiae for isoprenol production
- Complete integration of carbene-transfer chemistry into biosynthesis
- Expanding Extender Substrate Selection for Unnatural Polyketide Biosynthesis by Acyltransferase Domain Exchange within a Modular Polyketide Synthase
- Systematic engineering for production of anti-aging sunscreen compound in Pseudomonas putida
- A polyketide-based biosynthetic platform for diols, amino alcohols and hydroxy acids
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