Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-07
P
Priyangi A. Malaviarachchi
Clinical Research Coordinator
Also affiliated: University of Arkansas Medical Center (2018); PDL BioPharma (United States) (2006)
8 h-index
26 pubs
470 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Priyangi A. Malaviarachchi investigates host-pathogen interactions and immune responses, with a focus on infectious diseases affecting the lungs and reproductive tract. Her research utilizes *ex vivo* human precision-cut lung slices to study SARS-CoV-2 pathogenesis and evaluate antiviral drug efficacy. Malaviarachchi has also explored the role of specific immune mediators, such as Interleukin-17, in pulmonary inflammation during pneumonic plague and examined how interferon-gamma and antibodies contribute to immunity against *Chlamydia* infections, including their impact on female reproductive tract reinfections.
Her work extends to understanding disease severity in specific populations, as demonstrated by research on SARS-CoV-2 infection in a mouse model of Down Syndrome. Malaviarachchi also investigates the complex interplay of viral co-infections, examining alterations in cellular gene expression due to co-infection with Kaposi's Sarcoma-Associated Herpesvirus and SARS-CoV-2. She has published 24 papers, accumulating 465 citations, and holds an h-index of 8. Her collaborations include work with Srijon K. Banerjee, Lin‐Xi Li, Miguel A. B. Mercado, and Wuying Du at the University of Arkansas for Medical Sciences.
Metrics
- h-index: 8
- Publications: 26
- Citations: 470
Positions
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Clinical Research Coordinator publications 2007–2026University of Arkansas for Medical Sciences Institution web page
Selected Publications
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Nicotine and cotinine enhance SARS-CoV-2 entry through distinct but complementary mechanisms in human respiratory epithelial cells (2026)
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Alterations in Cellular Gene Expression Due to Co‐Infection With Kaposi's Sarcoma‐Associated Herpesvirus and SARS‐CoV‐2: Implications for Disease Severity (2024)
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An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy (2024)
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SARS-CoV-2 Infection Causes Heightened Disease Severity and Mortality in a Mouse Model of Down Syndrome (2024)
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Pulmonary Expression of Interleukin-17 Contributes to Neutrophil Infiltration into the Lungs during Pneumonic Plague (2023)
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An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy (2023)
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IFNγ and Antibody Synergize To Enhance Protective Immunity against Chlamydia Dissemination and Female Reproductive Tract Reinfections (2022)
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IFNγ and antibody synergize to enhance protective immunity against <i>Chlamydia</i> dissemination and female reproductive tract reinfections (2022)
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Innate IFN-γ Is Essential for Systemic Chlamydia muridarum Control in Mice, While CD4 T Cell-Dependent IFN-γ Production Is Highly Redundant in the Female Reproductive Tract (2020)
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Innate IFNγ is essential for systemic <i>Chlamydia</i> control while CD4 T cell-dependent IFNγ production is highly redundant in the female reproductive tract (2020)
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Antibody, but not B‐cell–dependent antigen presentation, plays an essential role in preventing <i>Chlamydia</i> systemic dissemination in mice (2020)
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PTEN is indispensable for cells to respond to MAPK inhibitors in myeloid leukemia (2018)
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Myeloma-Derived Exosomes and Soluble Factors Suppress Natural Killer Cell Function (2016)
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Stem Cell-like Characteristics of MM Plasma Cells Vary By ROS Levels: Implications for Targeted Therapy (2015)
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Low BCL11A Expression in the Myeloma Microenvironment at Diagnosis Is Associated with Early Development of MDS Cytogenetic Abnormalities and Poor Overall Survival (2014)
Collaboration Network
Top Collaborators
Bart Barlogie
University of Arkansas for Medical Sciences
6 shared publications
In database
- Infusion of haplo‐identical killer immunoglobulin‐like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation
- Stem Cell-like Characteristics of MM Plasma Cells Vary By ROS Levels: Implications for Targeted Therapy
- ATRA Upregulates Cell Surface CD1D on Myeloma Cells and Sensitizes Them to iNKT Cell-Mediated Lysis
- Activation and Expansion of Natural Killer (NK) Cells with Potent Cytotoxicity for Multiple Myeloma
- A Novel Mechanism of Action of Bortezomib: Proteasome Inhibition Down-Regulates HLA-Class I on Myeloma and Enhances NK Cell-Mediated Lysis.
Showing 5 of 6 shared publications
Tarun K. Garg
University of Arkansas for Medical Sciences (US)
5 shared publications
- Infusion of haplo‐identical killer immunoglobulin‐like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation
- Myeloma-Derived Exosomes and Soluble Factors Suppress Natural Killer Cell Function
- ATRA Upregulates Cell Surface CD1D on Myeloma Cells and Sensitizes Them to iNKT Cell-Mediated Lysis
- Activation and Expansion of Natural Killer (NK) Cells with Potent Cytotoxicity for Multiple Myeloma
- A Novel Mechanism of Action of Bortezomib: Proteasome Inhibition Down-Regulates HLA-Class I on Myeloma and Enhances NK Cell-Mediated Lysis.
Frits van Rhee
University of Arkansas for Medical Sciences
5 shared publications
In database
- Infusion of haplo‐identical killer immunoglobulin‐like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation
- Myeloma-Derived Exosomes and Soluble Factors Suppress Natural Killer Cell Function
- ATRA Upregulates Cell Surface CD1D on Myeloma Cells and Sensitizes Them to iNKT Cell-Mediated Lysis
- Activation and Expansion of Natural Killer (NK) Cells with Potent Cytotoxicity for Multiple Myeloma
- A Novel Mechanism of Action of Bortezomib: Proteasome Inhibition Down-Regulates HLA-Class I on Myeloma and Enhances NK Cell-Mediated Lysis.
Miguel A. B. Mercado
University of Arkansas for Medical Sciences
5 shared publications
In database
- Innate IFN-γ Is Essential for Systemic Chlamydia muridarum Control in Mice, While CD4 T Cell-Dependent IFN-γ Production Is Highly Redundant in the Female Reproductive Tract
- Antibody, but not B‐cell–dependent antigen presentation, plays an essential role in preventing <i>Chlamydia</i> systemic dissemination in mice
- IFNγ and Antibody Synergize To Enhance Protective Immunity against Chlamydia Dissemination and Female Reproductive Tract Reinfections
- Innate IFNγ is essential for systemic <i>Chlamydia</i> control while CD4 T cell-dependent IFNγ production is highly redundant in the female reproductive tract
- IFNγ and antibody synergize to enhance protective immunity against <i>Chlamydia</i> dissemination and female reproductive tract reinfections
Lin‐Xi Li
University of Arkansas for Medical Sciences
5 shared publications
In database
- Innate IFN-γ Is Essential for Systemic Chlamydia muridarum Control in Mice, While CD4 T Cell-Dependent IFN-γ Production Is Highly Redundant in the Female Reproductive Tract
- Antibody, but not B‐cell–dependent antigen presentation, plays an essential role in preventing <i>Chlamydia</i> systemic dissemination in mice
- IFNγ and Antibody Synergize To Enhance Protective Immunity against Chlamydia Dissemination and Female Reproductive Tract Reinfections
- Innate IFNγ is essential for systemic <i>Chlamydia</i> control while CD4 T cell-dependent IFNγ production is highly redundant in the female reproductive tract
- IFNγ and antibody synergize to enhance protective immunity against <i>Chlamydia</i> dissemination and female reproductive tract reinfections
Susann Szmania
University of Arkansas for Medical Sciences (US)
4 shared publications
- Infusion of haplo‐identical killer immunoglobulin‐like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation
- ATRA Upregulates Cell Surface CD1D on Myeloma Cells and Sensitizes Them to iNKT Cell-Mediated Lysis
- Activation and Expansion of Natural Killer (NK) Cells with Potent Cytotoxicity for Multiple Myeloma
- A Novel Mechanism of Action of Bortezomib: Proteasome Inhibition Down-Regulates HLA-Class I on Myeloma and Enhances NK Cell-Mediated Lysis.
Peter D. Emanuel
Winthrop Rockefeller Foundation
4 shared publications
In database
- PTEN transcript variants caused by illegitimate splicing in “aged” blood samples and EBV-transformed cell lines
- PTEN is indispensable for cells to respond to MAPK inhibitors in myeloid leukemia
- CREB Deficiency: A Potential Critical Factor for Selective GM-CSF Hypersensitivity in Juvenile Myelomonocytic Leukemia.
- Restoring Cell Responsiveness to GM-CSF and IL-3 by PTEN Is Via Controlling the Regulation of Egr-1 In TF-1a Cell Line
Jessica I. Gann
University of Arkansas for Medical Sciences
4 shared publications
In database
- Innate IFN-γ Is Essential for Systemic Chlamydia muridarum Control in Mice, While CD4 T Cell-Dependent IFN-γ Production Is Highly Redundant in the Female Reproductive Tract
- Myeloma-Derived Exosomes and Soluble Factors Suppress Natural Killer Cell Function
- IFNγ and Antibody Synergize To Enhance Protective Immunity against Chlamydia Dissemination and Female Reproductive Tract Reinfections
- Innate IFNγ is essential for systemic <i>Chlamydia</i> control while CD4 T cell-dependent IFNγ production is highly redundant in the female reproductive tract
Wuying Du
University of Arkansas for Medical Sciences
4 shared publications
In database
- Innate IFN-γ Is Essential for Systemic Chlamydia muridarum Control in Mice, While CD4 T Cell-Dependent IFN-γ Production Is Highly Redundant in the Female Reproductive Tract
- IFNγ and Antibody Synergize To Enhance Protective Immunity against Chlamydia Dissemination and Female Reproductive Tract Reinfections
- Innate IFNγ is essential for systemic <i>Chlamydia</i> control while CD4 T cell-dependent IFNγ production is highly redundant in the female reproductive tract
- IFNγ and antibody synergize to enhance protective immunity against <i>Chlamydia</i> dissemination and female reproductive tract reinfections
Roger D. Pechous
University of Arkansas for Medical Sciences (US)
4 shared publications
- An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy
- Pulmonary Expression of Interleukin-17 Contributes to Neutrophil Infiltration into the Lungs during Pneumonic Plague
- An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy
- SARS-CoV-2 Infection Causes Heightened Disease Severity and Mortality in a Mouse Model of Down Syndrome
Jumei Shi
University of Arkansas for Medical Sciences (US)
3 shared publications
- Infusion of haplo‐identical killer immunoglobulin‐like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation
- Activation and Expansion of Natural Killer (NK) Cells with Potent Cytotoxicity for Multiple Myeloma
- A Novel Mechanism of Action of Bortezomib: Proteasome Inhibition Down-Regulates HLA-Class I on Myeloma and Enhances NK Cell-Mediated Lysis.
Guido Tricot
University of Arkansas for Medical Sciences
3 shared publications
In database
- Infusion of haplo‐identical killer immunoglobulin‐like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation
- Activation and Expansion of Natural Killer (NK) Cells with Potent Cytotoxicity for Multiple Myeloma
- A Novel Mechanism of Action of Bortezomib: Proteasome Inhibition Down-Regulates HLA-Class I on Myeloma and Enhances NK Cell-Mediated Lysis.
John D. Shaughnessy
University of Arkansas for Medical Sciences
3 shared publications
In database
- Infusion of haplo‐identical killer immunoglobulin‐like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation
- Activation and Expansion of Natural Killer (NK) Cells with Potent Cytotoxicity for Multiple Myeloma
- A Novel Mechanism of Action of Bortezomib: Proteasome Inhibition Down-Regulates HLA-Class I on Myeloma and Enhances NK Cell-Mediated Lysis.
Joshua Epstein
University of Arkansas for Medical Sciences (US)
3 shared publications
- Myeloma-Derived Exosomes and Soluble Factors Suppress Natural Killer Cell Function
- Stem Cell-like Characteristics of MM Plasma Cells Vary By ROS Levels: Implications for Targeted Therapy
- Low BCL11A Expression in the Myeloma Microenvironment at Diagnosis Is Associated with Early Development of MDS Cytogenetic Abnormalities and Poor Overall Survival
Shmuel Yaccoby
University of Arkansas for Medical Sciences
3 shared publications
In database
- Stem Cell-like Characteristics of MM Plasma Cells Vary By ROS Levels: Implications for Targeted Therapy
- ATRA Upregulates Cell Surface CD1D on Myeloma Cells and Sensitizes Them to iNKT Cell-Mediated Lysis
- Low BCL11A Expression in the Myeloma Microenvironment at Diagnosis Is Associated with Early Development of MDS Cytogenetic Abnormalities and Poor Overall Survival
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