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Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Priyangi A. Malaviarachchi

Researcher

Also affiliated: Winthrop Rockefeller Foundation (2009–2010); PDL BioPharma (United States) (2006)

Faculty Researcher

8 h-index 24 pubs 468 cited

  • Humans
  • Animals
  • Mice
  • Female
  • COVID-19
  • SARS-CoV-2
  • Chlamydia Infections
  • Lung
  • Chlamydia muridarum
  • Reproductive Tract Infections
  • Cell Line
  • Killer Cells, Natural
  • Multiple Myeloma
  • Hematopoietic Stem Cell Transplantation
  • Receptors, KIR

Biography and Research Information

OverviewAI-generated summary

Priyangi A. Malaviarachchi investigates host-pathogen interactions and immune responses, with a focus on infectious diseases affecting the lungs and reproductive tract. Her research utilizes *ex vivo* human precision-cut lung slices to study SARS-CoV-2 pathogenesis and evaluate antiviral drug efficacy. Malaviarachchi has also explored the role of specific immune mediators, such as Interleukin-17, in pulmonary inflammation during pneumonic plague and examined how interferon-gamma and antibodies contribute to immunity against *Chlamydia* infections, including their impact on female reproductive tract reinfections.

Her work extends to understanding disease severity in specific populations, as demonstrated by research on SARS-CoV-2 infection in a mouse model of Down Syndrome. Malaviarachchi also investigates the complex interplay of viral co-infections, examining alterations in cellular gene expression due to co-infection with Kaposi's Sarcoma-Associated Herpesvirus and SARS-CoV-2. She has published 24 papers, accumulating 465 citations, and holds an h-index of 8. Her collaborations include work with Srijon K. Banerjee, Lin‐Xi Li, Miguel A. B. Mercado, and Wuying Du at the University of Arkansas for Medical Sciences.

Metrics

  • h-index: 8
  • Publications: 24
  • Citations: 468

Selected Publications

  • Nicotine and cotinine enhance SARS-CoV-2 entry through distinct but complementary mechanisms in human respiratory epithelial cells (2026)
    Journal of Virology DOI OpenAlex
  • Alterations in Cellular Gene Expression Due to Co‐Infection With Kaposi's Sarcoma‐Associated Herpesvirus and SARS‐CoV‐2: Implications for Disease Severity (2024)
    Journal of Medical Virology DOI OpenAlex
  • An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy (2024)
    Journal of Virology 12 citations DOI OpenAlex
  • SARS-CoV-2 Infection Causes Heightened Disease Severity and Mortality in a Mouse Model of Down Syndrome (2024)
    Biomedicines 2 citations DOI OpenAlex
  • Pulmonary Expression of Interleukin-17 Contributes to Neutrophil Infiltration into the Lungs during Pneumonic Plague (2023)
    Infection and Immunity 8 citations DOI OpenAlex
  • An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy (2023)
    bioRxiv (Cold Spring Harbor Laboratory) 3 citations DOI OpenAlex
  • IFNγ and Antibody Synergize To Enhance Protective Immunity against Chlamydia Dissemination and Female Reproductive Tract Reinfections (2022)
    Infection and Immunity 4 citations DOI OpenAlex
  • IFNγ and antibody synergize to enhance protective immunity against <i>Chlamydia</i> dissemination and female reproductive tract reinfections (2022)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Innate IFN-γ Is Essential for Systemic Chlamydia muridarum Control in Mice, While CD4 T Cell-Dependent IFN-γ Production Is Highly Redundant in the Female Reproductive Tract (2020)
    Infection and Immunity 21 citations DOI OpenAlex
  • Innate IFNγ is essential for systemic <i>Chlamydia</i> control while CD4 T cell-dependent IFNγ production is highly redundant in the female reproductive tract (2020)
    bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
  • Antibody, but not B‐cell–dependent antigen presentation, plays an essential role in preventing <i>Chlamydia</i> systemic dissemination in mice (2020)
    European Journal of Immunology 12 citations DOI OpenAlex
  • PTEN is indispensable for cells to respond to MAPK inhibitors in myeloid leukemia (2018)
    Cellular Signalling 9 citations DOI OpenAlex
  • Myeloma-Derived Exosomes and Soluble Factors Suppress Natural Killer Cell Function (2016)
    Blood 7 citations DOI OpenAlex
  • Stem Cell-like Characteristics of MM Plasma Cells Vary By ROS Levels: Implications for Targeted Therapy (2015)
    Blood 2 citations DOI OpenAlex
  • Low BCL11A Expression in the Myeloma Microenvironment at Diagnosis Is Associated with Early Development of MDS Cytogenetic Abnormalities and Poor Overall Survival (2014)
    Blood DOI OpenAlex

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Collaboration Network

29 Collaborators 5 Institutions 1 Country

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