Ricky D. Edmondson
Professor
Also affiliated: United States Food and Drug Administration (2004–2010); University of California, Los Angeles (2006); University of Arkansas Medical Center (2011–2018); Cancer Research UK (2009); University of Manchester (2009); Cancer Research UK Manchester Institute (2009); Texas A&M University (1994–1998)
Biochemistry & Molecular Biology, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Ricky D. Edmondson's research focuses on understanding molecular mechanisms underlying disease, with recent work investigating phase separation in cancer development, the role of serine protease HTRA1 in membranous nephropathy, and the regulation of bone mass by transferrin receptor 1-mediated iron uptake. He has also explored targeted cancer therapies through the development of PROTAC degraders for NSD3 and dual WDR5 and Ikaros targets. His laboratory group investigates protein interactions and their impact on cellular processes, including the role of TNRC18 in silencing endogenous retrotransposons and the identification of novel antigens in kidney diseases using mass spectrometry.
Edmondson is a Professor in the Department of Biochemistry & Molecular Biology at the University of Arkansas for Medical Sciences. His scholarship metrics include an h-index of 32, with over 91 publications and 4,560 citations. He has collaborated extensively with researchers at his institution, including Samuel G. Mackintosh, Alan J. Tackett, Aaron J. Storey, and Stephanie D. Byrum, with whom he has co-authored multiple publications.
Metrics
- h-index: 33
- Publications: 89
- Citations: 4,667
Positions
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Professor publications 2008–2026University of Arkansas for Medical Sciences Biochemistry & Molecular Biology, College of Medicine Institutional directory
Selected Publications
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Additional file 2 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 2 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 5 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 5 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Multiplexed Detection of Membranous Nephropathy Antigens by Multi-Reaction Monitoring Mass Spectrometry (2026)
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Abstract 6079: Resistance-specific proteogenomics in melanoma PDXs (2026)
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Proteomic Profiling of Complement Components in Glomerular Disease (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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277 Proteome turnover dynamics analysis uncovers E3 ligases that enhance T-cell persistence during exhaustion (2025)
Grants & Funding
As listed on this researcher's institutional profile.
- Identification of Druggable Targets to Complement Melanoma Therapy NIH Co-Investigator
- Development of biomarkers for improved classification of proliferative lupus nephritis NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases via Arkana Laboratories Co-Investigator
- Role of HELB in the Replication Stress Response Dr. Tacketts COBRA through ACRI NIH/Nat. Inst. of General Medical Sciences via Arkansas Children's Research Institute Co-Investigator
- Biomarkers of Early Renal Functional Decline in Type 2 Diabetes NIH Co-Investigator
- IDeA National Resource for Quantitative Proteomics NIH Co-Investigator
- Development of a Precision Medicine-Based Diagnostic Tool for Membranous Nephropathy NIH/National Institutes of Health via Arkana Laboratories Principal Investigator
- Discovery and Characterization of Novel Sepsis Proteome Biomarkers NIH Co-Investigator
Collaboration Network
Top Collaborators
- Phase separation drives aberrant chromatin looping and cancer development
- Microalbuminuria in Type 1 Diabetes Is Associated With Enhanced Excretion of the Endocytic Multiligand Receptors Megalin and Cubilin
- Indicators of responsiveness to immune checkpoint inhibitors
- PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
Showing 5 of 50 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- NELL1 is a target antigen in malignancy-associated membranous nephropathy
- Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis
- Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy
- PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation
Showing 5 of 45 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- Indicators of responsiveness to immune checkpoint inhibitors
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma
Showing 5 of 42 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- Indicators of responsiveness to immune checkpoint inhibitors
- PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
Showing 5 of 38 shared publications
- GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks
- A key role for Ctf4 in coupling the MCM2‐7 helicase to DNA polymerase α within the eukaryotic replisome
- Eukaryotic Replisome Components Cooperate to Process Histones During Chromosome Replication
- Mapping the Murine Cardiac 26S Proteasome Complexes
- SUMOylation of the GTPase Rac1 is required for optimal cell migration
Showing 5 of 18 shared publications
- Primary myeloma interaction and growth in coculture with healthy donor hematopoietic bone marrow
- Changes in the Expression of Proteasome Genes in Tumor Cells Following Short-Term Proteasome Inhibitor Therapy Predicts Survival in Multiple Myeloma Treated with Bortezomib-Containing Multi-Agent Chemotherapy
- Mesenchymal Stem Cells Preconditioned with Myeloma Cells from High-Risk Patients Support the Growth of Myeloma Cells from Low-Risk Patients
- Abstract 3516: EZH2 overexpression in myeloma patients shortens survival and in-vitro data supports a potential new targeted treatment strategy
- Multiple Myeloma Cells Modulate ICAM-3 To Evade Natural Killer Cell-Mediated Lysis
Showing 5 of 14 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
Showing 5 of 14 shared publications
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags
- Dynamic global acetylation remodeling during the yeast heat shock response
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome using Tandem Mass Tags
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 13 shared publications
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags
- Dynamic global acetylation remodeling during the yeast heat shock response
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome using Tandem Mass Tags
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 13 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
Showing 5 of 12 shared publications
- NELL1 is a target antigen in malignancy-associated membranous nephropathy
- Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis
- Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
Showing 5 of 11 shared publications
- Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 11 shared publications
- Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 11 shared publications
- Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 11 shared publications
- Phosphoproteomic Analyses Reveal Signaling Pathways That Facilitate Lytic Gammaherpesvirus Replication
- Amplification of JNK Signaling Is Necessary To Complete the Murine Gammaherpesvirus 68 Lytic Replication Cycle
- Myeloma-Derived Exosomes and Soluble Factors Suppress Natural Killer Cell Function
- Abstract 3516: EZH2 overexpression in myeloma patients shortens survival and in-vitro data supports a potential new targeted treatment strategy
- Multiple Myeloma Cells Modulate ICAM-3 To Evade Natural Killer Cell-Mediated Lysis
Showing 5 of 10 shared publications
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