Jeffrey A. Lewis Data-verified

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI

Associate Professor

Last publication 2026 Last refreshed 2026-05-22

faculty

17 h-index 72 pubs 864 cited

Biography and Research Information

OverviewAI-generated summary

Jeffrey A. Lewis is an Associate Professor at the University of Arkansas at Fayetteville. His research investigates the genetic and metabolic adaptations of microorganisms, particularly in response to environmental changes. Recent publications explore the genome of a nonphotosynthetic diatom, offering insights into its metabolic shift to heterotrophy and the constraints on the loss of photosynthesis. Other work examines the dynamic responses of diatoms to hypo-osmotic stress and their freshwater acclimation processes. Lewis also studies natural variation in yeast, identifying multiple pathways for increased stress resistance, and has developed laboratory activities for students to explore yeast isolation and brewing, as well as the microbiology of India Pale Ale production.

His work also extends to host-pathogen interactions, with research on diet-driven differences in host tolerance linked to global gene expression shifts in avian systems. Lewis has secured federal funding, including a $151,929 award from the NSF for the Fifth Annual NSF/MCB CAREER Awardee Conference. He collaborates with several researchers at the University of Arkansas at Fayetteville, including Stephanie E. Hood, Tara Stuecker, Andrew J. Alverson, and Kala M. Downey, with whom he has co-authored multiple publications. Lewis maintains an active lab website to share his research activities.

Metrics

  • h-index: 17
  • Publications: 72
  • Citations: 864

Selected Publications

  • Reproducibility Bundle for "MIC*: A Framework for Interpretable Analysis of Ordinal Viability Data" (2026)
  • Reproducibility Bundle for "MIC*: A Framework for Interpretable Analysis of Ordinal Viability Data" (2026)
  • Dynamic global acetylation remodeling during the yeast heat shock response (2026)
  • Dynamic global acetylation remodeling during the yeast heat shock response (2026)
  • Surprising regulatory plasticity for the conserved HOG pathway in diverse <i>Saccharomyces cerevisiae</i> strains (2025)
  • MIC*: A Framework for Interpretable Analysis of Ordinal Viability Data (2025)
    1 citation DOI OpenAlex
  • Improved vectors for retron-mediated CRISPR-Cas9 genome editing in <i>Saccharomyces cerevisiae</i> (2025)
  • Diet Driven Differences in Host Tolerance Are Linked to Shifts in Global Gene Expression in a Common Avian Host‐Pathogen System (2025)
    1 citation DOI OpenAlex
  • Dynamic global acetylation remodeling during the yeast heat shock response (2025)
    1 citation DOI OpenAlex
  • The Divergent Responses of Salinity Generalists to Hyposaline Stress Provide Insights Into the Colonisation of Freshwaters by Diatoms (2024)
    6 citations DOI OpenAlex
  • Diet driven differences in host tolerance are linked to shifts in global gene expression in a common avian host-pathogen system (2024)
    2 citations DOI OpenAlex
  • Improved vectors for retron-mediated CRISPR-Cas9 genome editing in <i>Saccharomyces cerevisiae</i> (2024)
  • Natural variation in yeast reveals multiple paths for acquiring higher stress resistance (2024)
    8 citations DOI OpenAlex
  • The divergent responses of salinity generalists to hyposaline stress provide insights into the colonization of freshwaters by diatoms (2024)
  • A hypothesis-based hop microbiology laboratory module testing the plausibility of the mythical origin of the India Pale Ale (2024)
    2 citations DOI OpenAlex

View all publications on OpenAlex →

Federal Grants 1 $151,929 total

NSF PI Jun 2024 - May 2025

Conference: Fifth Annual NSF/MCB CAREER Awardee Conference

Cross-BIO Activities $151,929

Collaboration Network

47 Collaborators 9 Institutions 2 Countries

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