Ruud P.M. Dings Data-verified
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Researcher
faculty
Research Areas
Biography and Research Information
OverviewAI-generated summary
Ruud P.M. Dings' research focuses on the intersection of cancer biology, immunology, and therapeutic development. His work investigates mechanisms of tumor growth, immune evasion, and the response of cancer cells and their microenvironment to various treatments, including radiation therapy, targeted therapies, and nanoparticle-based interventions.
Dr. Dings has explored the inflammatory activities associated with VEGF-targeted treatments and how they can reverse tumor endothelial cell anergy. His research also examines the bystander effects of spatially fractionated radiation therapy, considering its implications from molecular to organismal levels. He has investigated the role of galectins in cellular networks, revealing synergistic activities when mixed in vitro, and has contributed to the nanoscale investigation and control of photothermal effects using gold nanostructures. Additionally, his work has explored how dysbiotic stress influences tumor vasculature sensitivity to radiotherapy and c-Met inhibitors, and the biocompatibility of materials for dendritic cell applications.
With an h-index of 39 and over 5,000 citations across 123 publications, Dr. Dings is recognized as a highly cited researcher. He leads a research group and actively collaborates with researchers at the University of Arkansas for Medical Sciences, including Samir V. Jenkins and Robert J. Griffin, as well as Narasimhan Rajaram at the University of Arkansas.
Metrics
- h-index: 40
- Publications: 127
- Citations: 5,190
Selected Publications
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Abstract 4785: Thermal regulation of dysbiotic tumor vasculature (2026)
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Abstract 7625: Development of a blood-based tumor hypoxia detection assay (2026)
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Modified tumor uptake and biodistribution of nanoparticles coated with small extracellular vesicle membranes derived from distinct tumor cell lines (2026)
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Investigating Biomarkers of Radiation Resistance in Head and Neck Cancer Using Raman Spectroscopy (2025)
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Bystander Effects in Spatially Fractionated Radiation Therapy: From Molecule To Organism To Clinical Implications (2024)
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Morphological Effects and In Vitro Biological Mechanisms of Radiation-Induced Cell Killing by Gold Nanomaterials (2023)
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Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy (2022)
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Abstract 3529: T-cell trafficking and extravasation is suppressed in distal tumors during gastrointestinal tract dysbiosis (2022)
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Gold nanorods enhance different immune cells and allow for efficient targeting of CD4+ Foxp3+ Tregulatory cells (2021)
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Nanoscale investigation and control of photothermal action of gold nanostructure-coated surfaces (2021)
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Dysbiotic stress increases the sensitivity of the tumor vasculature to radiotherapy and c-Met inhibitors (2021)
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Dendritic cell biocompatibility of ether‐based urethane films (2021)
Federal Grants 1 $348,182 total
Improvement of cellular immunotherapy during dysbiosis- Resubmission
Collaboration Network
Top Collaborators
- Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy
- Bystander Effects in Spatially Fractionated Radiation Therapy: From Molecule To Organism To Clinical Implications
- Nanoscale investigation and control of photothermal action of gold nanostructure-coated surfaces
- CB-839 induces reversible dormancy in lung tumor-cells
- Dysbiotic stress increases the sensitivity of the tumor vasculature to radiotherapy and c-Met inhibitors
Showing 5 of 20 shared publications
- Bystander Effects in Spatially Fractionated Radiation Therapy: From Molecule To Organism To Clinical Implications
- Nanoscale investigation and control of photothermal action of gold nanostructure-coated surfaces
- CB-839 induces reversible dormancy in lung tumor-cells
- Dysbiotic stress increases the sensitivity of the tumor vasculature to radiotherapy and c-Met inhibitors
- Morphological Effects and In Vitro Biological Mechanisms of Radiation-Induced Cell Killing by Gold Nanomaterials
Showing 5 of 19 shared publications
- Gold nanorods enhance different immune cells and allow for efficient targeting of CD4+ Foxp3+ Tregulatory cells
- Dysbiotic stress increases the sensitivity of the tumor vasculature to radiotherapy and c-Met inhibitors
- Dendritic cell biocompatibility of ether‐based urethane films
- Abstract 1088: Acquired radiation resistance induces thiol-dependent cisplatin cross-resistance
- Acquired Radiation Resistance Induces Thiol-dependent Cisplatin Cross-resistance
Showing 5 of 16 shared publications
- Simulating cellular galectin networks by mixing galectins in vitro reveals synergistic activity
- Cysteine Oxidation in Human Galectin-1 Occurs Sequentially via a Folded Intermediate to a Fully Oxidized Unfolded Form
- Supplementary Materials and Methods from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
Showing 5 of 12 shared publications
- Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy
- Supplementary Materials and Methods from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
Showing 5 of 11 shared publications
- Supplementary Materials and Methods from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
Showing 5 of 10 shared publications
- Supplementary Materials and Methods from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
Showing 5 of 10 shared publications
- Abstract 3529: T-cell trafficking and extravasation is suppressed in distal tumors during gastrointestinal tract dysbiosis
- Data from Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Data from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Figures SF1 to SF4 and Tables TS1 to TS4 from Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
Showing 5 of 9 shared publications
- Abstract 1088: Acquired radiation resistance induces thiol-dependent cisplatin cross-resistance
- Acquired Radiation Resistance Induces Thiol-dependent Cisplatin Cross-resistance
- Data from Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Figures SF1 to SF4 and Tables TS1 to TS4 from Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Figures SF1 to SF4 and Tables TS1 to TS4 from Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
Showing 5 of 8 shared publications
- CB-839 induces reversible dormancy in lung tumor-cells
- Abstract 3529: T-cell trafficking and extravasation is suppressed in distal tumors during gastrointestinal tract dysbiosis
- Data from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
Showing 5 of 6 shared publications
- Supplementary Materials and Methods from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
Showing 5 of 6 shared publications
- Supplementary Materials and Methods from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
Showing 5 of 6 shared publications
- Supplementary Materials and Methods from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
Showing 5 of 6 shared publications
- Supplementary Materials and Methods from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
Showing 5 of 6 shared publications
- Supplementary Materials and Methods from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Data from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
- Supplementary Tables 1-3 from Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications
Showing 5 of 6 shared publications
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