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Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
S
Sree Vamsee Chintapalli
High Impact
Assistant Professor (non-tenure)
Also affiliated: University of Essex (2007–2013); Pennsylvania State University (2011–2015); University of Arkansas Medical Center (2017–2026); University of Kansas Medical Center (2025); Arkansas Children's Nutrition Center (2015–2026); Arkansas Children's Research Institute (2026); University of California, Davis (2012–2014)
26 h-index
105 pubs
2,014 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Sree Vamsee Chintapalli's research focuses on the impact of diet on the gut microbiome and its downstream effects on host health, particularly in the context of metabolic diseases and offspring development. Chintapalli has investigated how maternal high-fat diets can predispose offspring to steatohepatitis, associating these outcomes with alterations in epigenetic markers and the gut microbiome. This work has been explored in both mouse and swine models, demonstrating sexually dimorphic programming of offspring liver steatosis in mice.
Further research has examined how neonatal diet, including breast milk versus formula, influences the gut microbiota and metabolome profiles at various developmental stages. Studies have also specifically investigated the impact of formula feeding on small intestine morphology, microbial abundance, and the expression of key proteins like VE-cadherin and IL-10 in neonatal pigs. Additionally, Chintapalli's work includes exploring the effects of dietary supplementation, such as with strawberries, on the gut microbiome composition and functional potential in diabetic mice, and the role of diet in altering tryptophan metabolism from serotonin to tryptamine in the neonatal porcine colon.
Chintapalli has a significant publication record, with 98 total publications and 1,958 citations, contributing to an h-index of 26. This body of work has led to designations as a highly cited researcher. Key collaborators include Adepu Kiran Kumar (13 shared publications), Umesh D. Wankhade (8 shared publications), Brian D. Piccolo (8 shared publications), and Ying Zhong (4 shared publications), all from the University of Arkansas for Medical Sciences. Chintapalli leads an active research group and maintains an active lab website.
Metrics
- h-index: 26
- Publications: 105
- Citations: 2,014
Positions
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Informatics Core Senior Analyst 2025–presentArkansas Children's Nutrition Center Pediatrics ORCID
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Assistant Professor (Tenure Track) 2021–presentUniversity of Arkansas for Medical Sciences Pediatrics ORCID
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Assistant Professor (non-tenure) 2018–presentUniversity of Arkansas for Medical Sciences Pediatrics Institutional directory
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Assistant Professor 2018–presentArkansas Children Nutrition Center Pediatrics ORCID
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Bioinformatician (Informatics Team) 2016–2025Arkansas Children's Nutrition Center Pediatrics ORCID
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Instructor 2016–2018University of Arkansas for Medical Sciences Pediatrics ORCID
Selected Publications
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From known chemical space to unannotated metabolites: a cluster-guided retention-time driven framework for biologically informed annotation (2026)
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Mutation-induced heme pocket destabilization in myoglobinopathy (2026)
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MyD88 signaling in trophoblasts contributes to maternal high fat diet-associated alterations in placental gene expression and lipid profiles (2026)
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Mutation induced heme pocket destabilization in myoglobinopathy (2026)
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Mutation induced heme pocket destabilization in myoglobinopathy (2026)
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Integrating fingerprint prediction and physicochemical property filtering to annotate unknown metabolites from high-resolution MS/MS spectra (2026)
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Urinary sodium excretion is associated with increased body mass index: A cross-sectional analytical study among adults in Kuala Lumpur, Malaysia (2026)
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Enhancing Mitochondrial Function in Skeletal Muscle Cells through Metabolite Modulation: Therapeutic Implications for Muscle Metabolic Diseases (2025)
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Abstract 1547 Innovative Insights into Myoglobin-Metabolite Interactions and Muscle Cell Bioenergetics (2025)
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The Effect of Mhealth Interventions on Quality of Life in HIV Patients: A GRADE Assessed Systematic Review and Meta-Analysis (2025)
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Beyond the Known Metabolome: Predictive Strategies for Dark Matter Discovery (2025)
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Calorie restriction during gestation impacts maternal and offspring fecal microbiome in mice (2024)
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Unraveling Protein-Metabolite Interactions in Precision Nutrition: A Case Study of Blueberry-Derived Metabolites Using Advanced Computational Methods (2024)
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Quantitative Metabolomics-Driven Protein Target Prediction: A Computational Workflow for Precision Nutrition Discovery (2024)
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Effects of Statin and Annatto-extracted Tocotrienol Supplementation on Glucose Homeostasis, Bone Microstructure, and Gut Microbiota Composition in Obese Mice (2024)
Collaboration Network
Top Collaborators
Kartik Shankar
University of Colorado Anschutz (US)
31 shared publications
- Enhanced offspring predisposition to steatohepatitis with maternal high-fat diet is associated with epigenetic and microbiome alterations
- High-fat, high-fructose, high-cholesterol feeding causes severe NASH and cecal microbiota dysbiosis in juvenile Ossabaw swine
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
- Maternal High-Fat Diet Programs Offspring Liver Steatosis in a Sexually Dimorphic Manner in Association with Changes in Gut Microbial Ecology in Mice
Showing 5 of 31 shared publications
Sean H. Adams
Arkansas Children's Nutrition Center
21 shared publications
In database
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
- Sex differences in skeletal muscle revealed through fiber type, capillarity, and transcriptomics profiling in mice
- Molecular Dynamic Simulations Reveal the Structural Determinants of Fatty Acid Binding to Oxy-Myoglobin
- Novel Molecular Interactions of Acylcarnitines and Fatty Acids with Myoglobin
Showing 5 of 21 shared publications
Brian D. Piccolo
Arkansas Children's Nutrition Center
20 shared publications
In database
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
- Maternal High-Fat Diet Programs Offspring Liver Steatosis in a Sexually Dimorphic Manner in Association with Changes in Gut Microbial Ecology in Mice
- Dietary supplementation with strawberry induces marked changes in the composition and functional potential of the gut microbiome in diabetic mice
- Associations between maternal obesity and offspring gut microbiome in the first year of life
Showing 5 of 20 shared publications
Andriy Anishkin
University of Maryland, College Park
18 shared publications
In database
- Molecular Dynamic Simulations Reveal the Structural Determinants of Fatty Acid Binding to Oxy-Myoglobin
- Novel Molecular Interactions of Acylcarnitines and Fatty Acids with Myoglobin
- The S6 gate in regulatory Kv6 subunits restricts heteromeric K+ channel stoichiometry
- A versatile delivery vehicle for cellular oxygen and fuels or metabolic sensor? A review and perspective on the functions of myoglobin
- Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate
Showing 5 of 18 shared publications
Umesh D. Wankhade
Arkansas Children's Nutrition Center
17 shared publications
In database
- Enhanced offspring predisposition to steatohepatitis with maternal high-fat diet is associated with epigenetic and microbiome alterations
- High-fat, high-fructose, high-cholesterol feeding causes severe NASH and cecal microbiota dysbiosis in juvenile Ossabaw swine
- Maternal High-Fat Diet Programs Offspring Liver Steatosis in a Sexually Dimorphic Manner in Association with Changes in Gut Microbial Ecology in Mice
- Dietary supplementation with strawberry induces marked changes in the composition and functional potential of the gut microbiome in diabetic mice
- Sex-Specific Changes in Gut Microbiome Composition following Blueberry Consumption in C57BL/6J Mice
Showing 5 of 17 shared publications
Dipendra Bhandari
Arkansas Children's Nutrition Center (US)
13 shared publications
- Myoglobin Interaction with Lactate Rapidly Releases Oxygen: Studies on Binding Thermodynamics, Spectroscopy, and Oxygen Kinetics
- Exploring GPR109A Receptor Interaction with Hippuric Acid Using MD Simulations and CD Spectroscopy
- Myoglobin–Pyruvate Interactions: Binding Thermodynamics, Structure–Function Relationships, and Impact on Oxygen Release Kinetics
- Unraveling Protein-Metabolite Interactions in Precision Nutrition: A Case Study of Blueberry-Derived Metabolites Using Advanced Computational Methods
- Computational insights on molecular interactions of acifran with GPR109A and GPR109B
Showing 5 of 13 shared publications
Laxmi Yeruva
Arkansas Children's Hospital
11 shared publications
In database
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
- Neonatal Diet Impacts Bioregional Microbiota Composition in Piglets Fed Human Breast Milk or Infant Formula
Showing 5 of 11 shared publications
Kelly E. Mercer
Arkansas Children's Nutrition Center
10 shared publications
In database
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
- Maternal High-Fat Diet Programs Offspring Liver Steatosis in a Sexually Dimorphic Manner in Association with Changes in Gut Microbial Ecology in Mice
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
Showing 5 of 10 shared publications
Anne K. Bowlin
Arkansas Children's Nutrition Center
9 shared publications
In database
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
- Neonatal Diet Impacts Bioregional Microbiota Composition in Piglets Fed Human Breast Milk or Infant Formula
Showing 5 of 9 shared publications
Thomas M. Badger
Arkansas Children's Nutrition Center
8 shared publications
In database
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
- Human Breast-Milk Feeding Enhances the Humoral and Cell-Mediated Immune Response in Neonatal Piglets
Showing 5 of 8 shared publications
Manish Kumar Saraf
Arkansas Children's Nutrition Center (US)
7 shared publications
- Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
- Human Breast-Milk Feeding Enhances the Humoral and Cell-Mediated Immune Response in Neonatal Piglets
- Erratum to: Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
Showing 5 of 7 shared publications
Adepu Kiran Kumar
University of Arkansas for Medical Sciences
7 shared publications
In database
- A versatile delivery vehicle for cellular oxygen and fuels or metabolic sensor? A review and perspective on the functions of myoglobin
- Myoglobin Interaction with Lactate Rapidly Releases Oxygen: Studies on Binding Thermodynamics, Spectroscopy, and Oxygen Kinetics
- Exploring GPR109A Receptor Interaction with Hippuric Acid Using MD Simulations and CD Spectroscopy
- Myoglobin–Pyruvate Interactions: Binding Thermodynamics, Structure–Function Relationships, and Impact on Oxygen Release Kinetics
- Unraveling Protein-Metabolite Interactions in Precision Nutrition: A Case Study of Blueberry-Derived Metabolites Using Advanced Computational Methods
Showing 5 of 7 shared publications
Ying Zhong
Arkansas Children's Nutrition Center
6 shared publications
In database
- Enhanced offspring predisposition to steatohepatitis with maternal high-fat diet is associated with epigenetic and microbiome alterations
- Maternal High-Fat Diet Programs Offspring Liver Steatosis in a Sexually Dimorphic Manner in Association with Changes in Gut Microbial Ecology in Mice
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy
- Sex-Specific Changes in Gut Microbiome Composition following Blueberry Consumption in C57BL/6J Mice
Showing 5 of 6 shared publications
Lindsay Pack
Arkansas Children's Hospital
5 shared publications
In database
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
- Xenometabolite signatures in the UC Davis type 2 diabetes mellitus rat model revealed using a metabolomics platform enriched with microbe-derived metabolites
- Infant Formula Feeding Increases Hepatic Cholesterol 7α Hydroxylase (CYP7A1) Expression and Fecal Bile Acid Loss in Neonatal Piglets
Damian B. van Rossum
Pennsylvania State University (US)
4 shared publications
- Molecular Dynamic Simulations Reveal the Structural Determinants of Fatty Acid Binding to Oxy-Myoglobin
- Novel Molecular Interactions of Acylcarnitines and Fatty Acids with Myoglobin
- The S6 gate in regulatory Kv6 subunits restricts heteromeric K+ channel stoichiometry
- Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate
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