Sumit Sarkar Data-verified
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Biography and Research Information
OverviewAI-generated summary
Sumit Sarkar's research focuses on neurodegenerative diseases, particularly Alzheimer's disease, and the toxicological effects of various agents on the nervous system. His work investigates the role of metals, astrocytes, and amyloid plaques in the pathogenesis of Alzheimer's disease, utilizing animal models such as Sprague-Dawley rats and Tg-SwDI mice. Sarkar has explored methods for in vivo plaque detection and evaluated sex-related neuropathology and cognitive deficits in disease models.
His research also extends to the broader field of neurotoxicity, including quantitative analysis of brain toxicity following exposure to substances like trimethyltin. Sarkar has contributed to understanding the connection between Alzheimer's disease and type 3 diabetes, with a specific interest in health disparities within African American populations. He has also worked on developing and characterizing methods for localizing plaques and tangles in both rodent and human brain tissue.
Sarkar's scholarship metrics include an h-index of 35 and over 4,288 citations across 109 publications, designating him as a highly cited researcher. He actively collaborates with colleagues at the National Center for Toxicological Research, including James Raymick, Serguei Liachenko, Merle G. Paule, and E. Ellen Jones.
Metrics
- h-index: 35
- Publications: 109
- Citations: 4,316
Selected Publications
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Potential link of high fat diet and mRNA expression of Alzheimer's disease-related genes in the enteric mucosa of a rat model of Alzheimer's disease (2025)
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Developing non-invasive molecular markers for early risk assessment of Alzheimer's disease (2025)
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The incorporation of MALDI mass spectrometry imaging in studies to identify markers of toxicity following in utero opioid exposures in mouse fetuses (2024)
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Evaluation and Characterization of Modified K114 Method to LocalizePlaques in Rodent and Plaques and Tangles in Human Brain Tissue (2024)
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In vivo mapping of rat brain partial white matter content using hexachlorophene-induced neurotoxicity model (2024)
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A novel humanized Tau‐FAD mice represent a robust model for studying AD‐related dysfunction (2023)
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The role of astrocytes in the glymphatic network: a narrative review (2023)
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Combining tissue clearing and Fluoro-Jade C labeling for neurotoxicity assessments (2023)
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Assessment of sex-related neuropathology and cognitive deficits in the Tg-SwDI mouse model of Alzheimer’s disease (2022)
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Development of early biomarkers of Alzheimer's disease: A precision medicine perspective (2022)
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Evaluation of Styrylbenzene analog- FSB and its affinity to bind parenchymal plaques and tangles in patients of Alzheimer’s disease (2022)
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Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity (2021)
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Role of metals in Alzheimer’s disease (2021)
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Alzheimer’s disease: a step closer to understanding type 3 diabetes in African Americans (2021)
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Global Neurotoxicity: Quantitative Analysis of Rat Brain Toxicity Following Exposure to Trimethyltin (2021)
Collaboration Network
Top Collaborators
- In vivo demonstration of Congo Red labeled amyloid plaques via perfusion in the Alzheimer disease rat model
- Assessment of sex-related neuropathology and cognitive deficits in the Tg-SwDI mouse model of Alzheimer’s disease
- Global Neurotoxicity: Quantitative Analysis of Rat Brain Toxicity Following Exposure to Trimethyltin
- Evaluation and Characterization of Modified K114 Method to LocalizePlaques in Rodent and Plaques and Tangles in Human Brain Tissue
- Evaluation of Styrylbenzene analog- FSB and its affinity to bind parenchymal plaques and tangles in patients of Alzheimer’s disease
Showing 5 of 7 shared publications
- Role of metals in Alzheimer’s disease
- In vivo demonstration of Congo Red labeled amyloid plaques via perfusion in the Alzheimer disease rat model
- Evaluation and Characterization of Modified K114 Method to LocalizePlaques in Rodent and Plaques and Tangles in Human Brain Tissue
- Evaluation of Styrylbenzene analog- FSB and its affinity to bind parenchymal plaques and tangles in patients of Alzheimer’s disease
- Potential link of high fat diet and mRNA expression of Alzheimer's disease-related genes in the enteric mucosa of a rat model of Alzheimer's disease
Showing 5 of 6 shared publications
- In vivo demonstration of Congo Red labeled amyloid plaques via perfusion in the Alzheimer disease rat model
- Assessment of sex-related neuropathology and cognitive deficits in the Tg-SwDI mouse model of Alzheimer’s disease
- Evaluation and Characterization of Modified K114 Method to LocalizePlaques in Rodent and Plaques and Tangles in Human Brain Tissue
- Evaluation of Styrylbenzene analog- FSB and its affinity to bind parenchymal plaques and tangles in patients of Alzheimer’s disease
- Role of metals in Alzheimer’s disease
- The role of astrocytes in the glymphatic network: a narrative review
- Evaluation of Styrylbenzene analog- FSB and its affinity to bind parenchymal plaques and tangles in patients of Alzheimer’s disease
- Development of early biomarkers of Alzheimer's disease: A precision medicine perspective
- Global Neurotoxicity: Quantitative Analysis of Rat Brain Toxicity Following Exposure to Trimethyltin
- In vivo mapping of rat brain partial white matter content using hexachlorophene-induced neurotoxicity model
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Global Neurotoxicity: Quantitative Analysis of Rat Brain Toxicity Following Exposure to Trimethyltin
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Alzheimer’s disease: a step closer to understanding type 3 diabetes in African Americans
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Development of early biomarkers of Alzheimer's disease: A precision medicine perspective
- A novel humanized Tau‐FAD mice represent a robust model for studying AD‐related dysfunction
- Global Neurotoxicity: Quantitative Analysis of Rat Brain Toxicity Following Exposure to Trimethyltin
- Global Neurotoxicity: Quantitative Analysis of Rat Brain Toxicity Following Exposure to Trimethyltin
- Alzheimer’s disease: a step closer to understanding type 3 diabetes in African Americans
- Alzheimer’s disease: a step closer to understanding type 3 diabetes in African Americans
- Alzheimer’s disease: a step closer to understanding type 3 diabetes in African Americans
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
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