Susan M. Burks
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
General Health Scientist
Also affiliated: United States Food and Drug Administration (2013–2022)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Susan M. Burks' research focuses on mechanisms of neurotoxicity and neurodegeneration, with recent investigations into the potential impact of SARS-CoV-2 on the central nervous system. She has explored whether the virus can infect the brain via the olfactory bulb or the blood-brain barrier, and has studied its potential to cause dopaminergic degeneration in human neuronal models. Her work also includes the evaluation of circulating biomarkers for neurotoxicity, using proteomics to identify endpoints of central nervous system toxicity in rodent models. Additionally, Burks has conducted genotoxicity evaluations using primary hepatocytes isolated from rhesus macaques. Her research network includes collaborators such as John Talpos and Manuel Alejandro Ramirez-Lee from the National Center for Toxicological Research. Burks' scholarly output includes 10 publications, with an h-index of 7 and 327 total citations.
Metrics
- h-index: 10
- Publications: 16
- Citations: 623
Positions
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General Health Scientist 2008–presentNational Center for Toxicological Research Office of Research ORCID
Selected Publications
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Autophagy and protein aggregation as a mechanism of dopaminergic degeneration in a primary human dopaminergic neuronal model (2022)
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Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity (2021)
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Genotoxicity evaluation using primary hepatocytes isolated from rhesus macaque (Macaca mulatta) (2021)
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Can SARS-CoV-2 infect the central nervous system via the olfactory bulb or the blood-brain barrier? (2021)
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Tauroursodeoxycholic acid (TUDCA) is neuroprotective in a chronic mouse model of Parkinson’s disease (2020)
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Regions of the basal ganglia and primary olfactory system are most sensitive to neurodegeneration after extended sevoflurane anesthesia in the perinatal rat (2020)
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Microglial activation and responses to vasculature that result from an acute LPS exposure (2020)
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Stretch-Induced Deformation as a Model to Study Dopaminergic Dysfunction in Traumatic Brain Injury (2019)
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Amyloid Beta 25–35 induces blood-brain barrier disruption in vitro (2019)
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Neuroprotective effects of acetyl-l-carnitine (ALC) in a chronic MPTP-induced Parkinson’s disease mouse model: Endothelial and microglial effects (2019)
Collaboration Network
Top Collaborators
- Can SARS-CoV-2 infect the central nervous system via the olfactory bulb or the blood-brain barrier?
- Tauroursodeoxycholic acid (TUDCA) is neuroprotective in a chronic mouse model of Parkinson’s disease
- Amyloid Beta 25–35 induces blood-brain barrier disruption in vitro
- Stretch-Induced Deformation as a Model to Study Dopaminergic Dysfunction in Traumatic Brain Injury
- Autophagy and protein aggregation as a mechanism of dopaminergic degeneration in a primary human dopaminergic neuronal model
Showing 5 of 6 shared publications
- Tauroursodeoxycholic acid (TUDCA) is neuroprotective in a chronic mouse model of Parkinson’s disease
- Amyloid Beta 25–35 induces blood-brain barrier disruption in vitro
- Microglial activation and responses to vasculature that result from an acute LPS exposure
- Neuroprotective effects of acetyl-l-carnitine (ALC) in a chronic MPTP-induced Parkinson’s disease mouse model: Endothelial and microglial effects
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Tauroursodeoxycholic acid (TUDCA) is neuroprotective in a chronic mouse model of Parkinson’s disease
- Microglial activation and responses to vasculature that result from an acute LPS exposure
- Neuroprotective effects of acetyl-l-carnitine (ALC) in a chronic MPTP-induced Parkinson’s disease mouse model: Endothelial and microglial effects
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Tauroursodeoxycholic acid (TUDCA) is neuroprotective in a chronic mouse model of Parkinson’s disease
- Neuroprotective effects of acetyl-l-carnitine (ALC) in a chronic MPTP-induced Parkinson’s disease mouse model: Endothelial and microglial effects
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Tauroursodeoxycholic acid (TUDCA) is neuroprotective in a chronic mouse model of Parkinson’s disease
- Neuroprotective effects of acetyl-l-carnitine (ALC) in a chronic MPTP-induced Parkinson’s disease mouse model: Endothelial and microglial effects
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Can SARS-CoV-2 infect the central nervous system via the olfactory bulb or the blood-brain barrier?
- Amyloid Beta 25–35 induces blood-brain barrier disruption in vitro
- Stretch-Induced Deformation as a Model to Study Dopaminergic Dysfunction in Traumatic Brain Injury
- Amyloid Beta 25–35 induces blood-brain barrier disruption in vitro
- Stretch-Induced Deformation as a Model to Study Dopaminergic Dysfunction in Traumatic Brain Injury
- Autophagy and protein aggregation as a mechanism of dopaminergic degeneration in a primary human dopaminergic neuronal model
- Can SARS-CoV-2 infect the central nervous system via the olfactory bulb or the blood-brain barrier?
- Regions of the basal ganglia and primary olfactory system are most sensitive to neurodegeneration after extended sevoflurane anesthesia in the perinatal rat
- Genotoxicity evaluation using primary hepatocytes isolated from rhesus macaque (Macaca mulatta)
- Can SARS-CoV-2 infect the central nervous system via the olfactory bulb or the blood-brain barrier?
- Amyloid Beta 25–35 induces blood-brain barrier disruption in vitro
- Amyloid Beta 25–35 induces blood-brain barrier disruption in vitro
- Autophagy and protein aggregation as a mechanism of dopaminergic degeneration in a primary human dopaminergic neuronal model
- Amyloid Beta 25–35 induces blood-brain barrier disruption in vitro
- Autophagy and protein aggregation as a mechanism of dopaminergic degeneration in a primary human dopaminergic neuronal model
- Microglial activation and responses to vasculature that result from an acute LPS exposure
- Regions of the basal ganglia and primary olfactory system are most sensitive to neurodegeneration after extended sevoflurane anesthesia in the perinatal rat
- Microglial activation and responses to vasculature that result from an acute LPS exposure
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Tauroursodeoxycholic acid (TUDCA) is neuroprotective in a chronic mouse model of Parkinson’s disease
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Microglial activation and responses to vasculature that result from an acute LPS exposure
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