Murat Gökden
Professor
Also affiliated: University of Iowa (2019); Saint Barnabas Medical Center (2022); Arkansas Children's Hospital (2012–2025); The University of Texas MD Anderson Cancer Center (2001); Harvard University (2018); Dokuz Eylül University (1996); University of Washington (1998); Washington University in St. Louis (1997–2001); University of Arkansas Medical Center (2009–2026); Truman Medical Center (2004); University of Rochester Medicine (2022); Massachusetts General Hospital (2018); Central Arkansas Veterans Healthcare System (2004–2005); MSN Laboratories (India) (2019); UMass Memorial Medical Center (2001); United States and Canadian Academy of Pathology (2003); University of Missouri–Kansas City (2004)
Pathology, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Murat Gökden's research focuses on the molecular mechanisms and diagnostic markers of various cancers, particularly ovarian and uterine serous papillary cancers, as well as central nervous system tumors. He has investigated gene expression profiles in ovarian tumors to identify potential markers for diagnosis and therapy, and has studied the overexpression of HER-2/neu in uterine serous papillary cancer.
His work also extends to neuropathology, including research on chordoma and chondrosarcoma, poorly differentiated chordomas, and malignant peripheral nerve sheath tumors. Gökden has examined neuronal caspase-3 activation in Alzheimer's disease and investigated peripheral nervous system pathology in fragile X tremor/ataxia syndrome. He has also been involved in research related to HPV vaccination for cervical cancer.
Gökden holds multiple professional certifications in Anatomic Pathology, Neuropathology, and Cytopathology. He is recognized as a high-impact researcher with a significant publication record and has secured federal funding for his investigations into cancer immunotherapy and immune dysregulation. He leads a research group and collaborates with colleagues at the University of Arkansas for Medical Sciences.
Research Overview
Academic Appointment • Professor of Pathology Department - Pathology Education • Fellowship: Cytopathology-University of Arkansas for Medical Sciences • Fellowship: Surgical Pathology-University of Texas, MD Anderson Cancer Center • Fellowship: Neuropathology-Washington University in St. Louis • Residency: Anatomic Pathology- Washington University in St. Louis • Medical School: Dokuz Eylul Medical School, Izmir, Turkey Professional Certifications • American Board of Pathology-Anatomic Pathology • American Board of Pathology-Neuropathology • American Board of Pathology-Cytopathology
Metrics
- h-index: 27
- Publications: 164
- Citations: 2,971
Positions
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Professor publications 2001–2026University of Arkansas for Medical Sciences Pathology, College of Medicine Institutional directory
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University of Arkansas for Medical Sciences publications 2001–2026ORCID
Selected Publications
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Special Biopsies in Pathology: Nerve Biopsy (2026)
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Special Biopsies in Pathology: Muscle Biopsy (2026)
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Spinal neurosarcoidosis mimicking intramedullary tumors without systemic symptoms: Report of two cases and a systematic review (2026)
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Pathologic Variability Associated With Phenotypic Differences in Siblings With ACTA1 Myopathy (2026)
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Illuminating Blurry Vision: Visualization of Corneal Protein Deposition With Immunofluorescence in Two Illustrative Case Reports (2026)
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Can Transcutaneous Vagus Nerve Stimulation be Effective After Rats’ Spinal Cord Injury? (2026)
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Intracranial mesenchymal tumor, FET::CREB fusion-positive: An integrative analysis of 81 cases (2026)
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PATH-79. High-grade astrocytoma with piloid features (HGAP) comprehensive update: histological grading, molecular markers and clinical outcomes (2025)
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Targeted Inhibition in Pediatric MET and ALK-Altered Hemispheric Gliomas: Objective Responses Followed by Treatment Resistance (2025)
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Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models (2025)
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Signal Recognition Particle Myopathy With Cardiac Manifestations in Rheumatoid Arthritis (2025)
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Surgery of peritorcular meningiomas: the structural basis for preservation of torcular venous flow (2025)
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Navigating molecular neuropathology of CNS neoplasms for the practicing surgical pathologist (2025)
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Can Transcutaneous Vagus Nerve Stimulation Be Effective after Rats’ Spinal Cord Injury? (2025)
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A rare presentation of pediatric germinoma mimicking optic pathway glioma: illustrative case (2025)
Federal Grants 2 $872,121 total
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Early Events in Alzheimer Pathogenesis NIH Co-Investigator
Collaboration Network
Top Collaborators
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- SMARC-B1 deficient sinonasal carcinoma metastasis to the brain with next generation sequencing data: a case report of perineural invasion progressing to leptomeningeal invasion
- Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon
- Pituitary Metastatic Composite Tumors: A Case Report with Next-Generation Sequencing and Review of the Literature
- Proteogenomic analysis of melanoma brain metastases from distinct anatomical sites identifies pathways of metastatic progression
Showing 5 of 14 shared publications
- The Utility of PAX-2 in Distinguishing Metastatic Clear Cell Renal Cell Carcinoma From its Morphologic Mimics
- The Utility of Pax-2 and Renal Cell Carcinoma Marker Immunohistochemistry in Distinguishing Papillary Renal Cell Carcinoma From Nonrenal Cell Neoplasms With Papillary Features
- Diagnostic Utility of Renal Cell Carcinoma Marker in Cytopathology
- The utility of Pax‐2 as an immunohistochemical marker for renal cell carcinoma in cytopathology
- Expression of CD138 (Syndecan-1) in Renal Cell Carcinoma is Reduced With Increasing Nuclear Grade
Showing 5 of 9 shared publications
- Neuropathology Education Using Social Media
- Significance of Staining Intensity in Ki-67 Proliferation Index in Meningiomas, and a Critical Review of the Literature on Proliferation Index Assessment.
- Long-read sequencing for brain tumors
- SMARCA4-deficient central nervous system metastases: A case series and systematic review
- Miyoshi Muscular Dystrophy Due to Novel Splice Site Variants in DYSF Gene
Showing 5 of 9 shared publications
- BAG3 Myopathy Presenting With Prominent Neuropathic Phenotype and No Cardiac or Respiratory Involvement: A Case Report and Literature Review
- Toxic Myopathy due to Antidopaminergic Medication Without Neuroleptic Malignant Syndrome
- A novel noncoding FKRP mutation in early onset limb-girdle muscular dystrophy
- Limb-Girdle Muscular Dystrophy R9 due to a Novel Complex Insertion/Duplication Variant in FKRP Gene
- Anti-dopaminergic medication related myopathy causing respiratory muscle weakness without neuroleptic malignant syndrome (P3.461)
Showing 5 of 6 shared publications
- Mitochondrial Ultrastructural Defects in NDUFS3-Related Disorder
- BAG3 Myopathy Presenting With Prominent Neuropathic Phenotype and No Cardiac or Respiratory Involvement: A Case Report and Literature Review
- A novel noncoding FKRP mutation in early onset limb-girdle muscular dystrophy
- Limb-Girdle Muscular Dystrophy R9 due to a Novel Complex Insertion/Duplication Variant in FKRP Gene
- Miyoshi Muscular Dystrophy Due to Novel Splice Site Variants in DYSF Gene
Showing 5 of 6 shared publications
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Proteogenomic analysis of melanoma brain metastases from distinct anatomical sites identifies pathways of metastatic progression
- Genomic and Transcriptomic Profiling of Brain Metastases
- Primary glioblastoma of the cauda equina with molecular and histopathological characterization: Case report
- Long-read sequencing for brain tumors
Showing 5 of 6 shared publications
- Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium: Identification of candidate molecular markers for ovarian cancer diagnosis and therapy
- Vaccination with HPV-18 E7–Pulsed Dendritic Cells in a Patient with Metastatic Cervical Cancer
- Discrimination between uterine serous papillary carcinomas and ovarian serous papillary tumours by gene expression profiling
- Selection of HER-2/neu-positive tumor cells in early stage cervical cancer: implications for Herceptin-mediated therapy
- Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models
- Loss of SMARCB1/INI1 expression in poorly differentiated chordomas
- Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes
- Papillary tumor of the pineal region with synchronous suprasellar focus and novel cytogenetic features
- A novel rotation and scale-invariant deep learning framework leveraging conical transformers for precise differentiation between meningioma and solitary fibrous tumor
- Author Correction: Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes
- Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes
- Intracranial mesenchymal tumor, FET::CREB fusion-positive: An integrative analysis of 81 cases
- Author Correction: Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes
- PATH-34. CLINICOPATHOLOGIC CHARACTERIZATION OF DIFFUSE PEDIATRIC-TYPE HIGH-GRADE GLIOMA, H3-WILDTYPE AND IDH-WILDTYPE: AN AGGRESSIVE AND GENOMICALLY COMPLEX GROUP OF TUMORS AFFECTING CHILDREN AND ADULTS
- PATH-79. High-grade astrocytoma with piloid features (HGAP) comprehensive update: histological grading, molecular markers and clinical outcomes
- Diffuse Leptomeningeal Glioneuronal Tumor: First Description of Metastasis to the Lung and Bone Marrow
- Operative planning for a functional precision medicine assay of recurrent high-grade glioma: illustrative case
- Functional precision medicine assay for recurrent meningioma: a proof of principle. Illustrative case
- NCMP-15. A CASE OF SYSTEMIC METASTATIC DIFFUSE LEPTOMENINGEAL GLIONEURAL TUMOR
- Navigating molecular neuropathology of CNS neoplasms for the practicing surgical pathologist
- Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium: Identification of candidate molecular markers for ovarian cancer diagnosis and therapy
- Vaccination with HPV-18 E7–Pulsed Dendritic Cells in a Patient with Metastatic Cervical Cancer
- Discrimination between uterine serous papillary carcinomas and ovarian serous papillary tumours by gene expression profiling
- Selection of HER-2/neu-positive tumor cells in early stage cervical cancer: implications for Herceptin-mediated therapy
- Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium: Identification of candidate molecular markers for ovarian cancer diagnosis and therapy
- Vaccination with HPV-18 E7–Pulsed Dendritic Cells in a Patient with Metastatic Cervical Cancer
- Discrimination between uterine serous papillary carcinomas and ovarian serous papillary tumours by gene expression profiling
- Selection of HER-2/neu-positive tumor cells in early stage cervical cancer: implications for Herceptin-mediated therapy
- PEHO syndrome: KIF1A mutation and decreased activity of mitochondrial respiratory chain complex
- Clinicopathologic Findings of CARS2 Mutation
- Mitochondrial Ultrastructural Defects in NDUFS3-Related Disorder
- Absence of seizures in Rasmussen encephalitis with active inflammation
- Solitary fibrous tumors of the spine: a pediatric case report with a comprehensive review of the literature
- Absence of seizures in Rasmussen encephalitis with active inflammation
- ETMR-15. Central Nervous System Embryonal Tumor with EWSR1 translocation: Evolving changes in histology, sequencing, and epigenetics at relapse in 2 patients and potential treatment implications
- A rare presentation of pediatric germinoma mimicking optic pathway glioma: illustrative case
- Toxic Myopathy due to Antidopaminergic Medication Without Neuroleptic Malignant Syndrome
- Glioblastoma, IDH ‐Wildtype, CNS WHO Grade 4, Associated with Deep Brain Stimulation in a Patient with Essential Tremor: Report of a Case with Molecular Characterization, and Review of the Literature
- Clinical Reasoning: A 73-year-old man with diplopia and ataxia
- Anti-dopaminergic medication related myopathy causing respiratory muscle weakness without neuroleptic malignant syndrome (P3.461)
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