Murat Gökden
Professor
Also affiliated: University of Iowa (2019); Saint Barnabas Medical Center (2022); Arkansas Children's Hospital (2012–2025); University of Wisconsin System (2004); The University of Texas MD Anderson Cancer Center (2001); Dokuz Eylül University (1996); Washington University in St. Louis (1997–2001); University of Arkansas Medical Center (2009–2026); Truman Medical Center (2004); University of Rochester Medicine (2022); Massachusetts General Hospital (2018); Memorial Medical Center (2001); Scriptorium (2003); American Association for Dental Research (2003); Central Arkansas Veterans Healthcare System (2004–2005); Mallinckrodt (United States) (1998); NOF Corporation (Japan) (2017); University of Applied Management Studies (2020–2025); Universidad de Manizales (2024); Institute for Conflict Research (2024); Winthrop Rockefeller Foundation (2023); Riverkeeper (2001–2003); UMass Memorial Medical Center (2001); University of Missouri–Kansas City (2004)
Faculty Researcher
Pathology, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Murat Gökden is a Professor of Pathology at the University of Arkansas for Medical Sciences. His research focuses on the molecular diagnostics and treatment strategies for central nervous system tumors. He has investigated the clinical utility of whole-genome DNA methylation profiling for primary molecular diagnosis of brain tumors and explored functional precision medicine pipelines that combine comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma. His work also includes studying the stem cell lineages and gene expression patterns in astroblastomas and identifying prognostic determinants for specific fusion-positive intracranial mesenchymal tumors.
Gökden leads a research group and has a prolific publication record, with 162 total publications and an h-index of 27, accumulating over 2,947 citations. He has secured federal funding for his research, including two NIH grants totaling $872,121. One grant, for $178,819, supports his work as PI on mechanisms of Th17-DC immunotherapy for ovarian cancer. He also serves as Co-PI on a $693,302 NIH grant investigating the role of platelets in radiation-induced immune dysregulation.
His clinical expertise is reflected in his fellowships in Cytopathology, Surgical Pathology, and Neuropathology, as well as his board certifications in Anatomic Pathology and Neuropathology. Gökden collaborates with several researchers at the University of Arkansas for Medical Sciences, including Analiz Rodriguez, J. Stephen Nix, Sateesh Jayappa, and Christopher P. Wardell.
Research Overview
Academic Appointment • Professor of Pathology Department - Pathology Education • Fellowship: Cytopathology-University of Arkansas for Medical Sciences • Fellowship: Surgical Pathology-University of Texas, MD Anderson Cancer Center • Fellowship: Neuropathology-Washington University in St. Louis • Residency: Anatomic Pathology- Washington University in St. Louis • Medical School: Dokuz Eylul Medical School, Izmir, Turkey Professional Certifications • American Board of Pathology-Anatomic Pathology • American Board of Pathology-Neuropathology • American Board of Pathology-Cytopathology
Metrics
- h-index: 27
- Publications: 164
- Citations: 2,961
Selected Publications
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Special Biopsies in Pathology: Nerve Biopsy (2026)
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Special Biopsies in Pathology: Muscle Biopsy (2026)
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Spinal neurosarcoidosis mimicking intramedullary tumors without systemic symptoms: Report of two cases and a systematic review (2026)
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Pathologic Variability Associated With Phenotypic Differences in Siblings With <scp>ACTA1</scp> Myopathy (2026)
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Illuminating Blurry Vision: Visualization of Corneal Protein Deposition With Immunofluorescence in Two Illustrative Case Reports (2026)
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Can Transcutaneous Vagus Nerve Stimulation be Effective After Rats’ Spinal Cord Injury? (2026)
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Intracranial mesenchymal tumor, FET::CREB fusion-positive: An integrative analysis of 81 cases (2026)
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PATH-79. High-grade astrocytoma with piloid features (HGAP) comprehensive update: histological grading, molecular markers and clinical outcomes (2025)
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Targeted Inhibition in Pediatric MET and ALK-Altered Hemispheric Gliomas: Objective Responses Followed by Treatment Resistance (2025)
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Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models (2025)
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Signal Recognition Particle Myopathy With Cardiac Manifestations in Rheumatoid Arthritis (2025)
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Surgery of peritorcular meningiomas: the structural basis for preservation of torcular venous flow (2025)
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Navigating molecular neuropathology of CNS neoplasms for the practicing surgical pathologist (2025)
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Can Transcutaneous Vagus Nerve Stimulation Be Effective after Rats’ Spinal Cord Injury? (2025)
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A rare presentation of pediatric germinoma mimicking optic pathway glioma: illustrative case (2025)
Federal Grants 2 $872,121 total
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Early Events in Alzheimer Pathogenesis NIH Co-Investigator
Collaboration Network
Top Collaborators
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon
- Genomic and Transcriptomic Profiling of Brain Metastases
- Primary glioblastoma of the cauda equina with molecular and histopathological characterization: Case report
- SMARCA4-deficient central nervous system metastases: A case series and systematic review
Showing 5 of 11 shared publications
- SMARCA4-deficient central nervous system metastases: A case series and systematic review
- Miyoshi Muscular Dystrophy Due to Novel Splice Site Variants in <i>DYSF</i> Gene
- Operative planning for a functional precision medicine assay of recurrent high-grade glioma: illustrative case
- A rare case of atypical intradural extramedullary glioblastoma diagnosed utilizing next-generation sequencing and methylation profiling: illustrative case
- Long-read sequencing for brain tumors
Showing 5 of 7 shared publications
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Genomic and Transcriptomic Profiling of Brain Metastases
- Primary glioblastoma of the cauda equina with molecular and histopathological characterization: Case report
- Long-read sequencing for brain tumors
- Intracranial hematolymphoid malignancies: A case series with molecular characterization
- Diffuse Leptomeningeal Glioneuronal Tumor: First Description of Metastasis to the Lung and Bone Marrow
- Operative planning for a functional precision medicine assay of recurrent high-grade glioma: illustrative case
- Functional precision medicine assay for recurrent meningioma: a proof of principle. Illustrative case
- NCMP-15. A CASE OF SYSTEMIC METASTATIC DIFFUSE LEPTOMENINGEAL GLIONEURAL TUMOR
- Navigating molecular neuropathology of CNS neoplasms for the practicing surgical pathologist
- Mitochondrial Ultrastructural Defects in NDUFS3-Related Disorder
- Limb-Girdle Muscular Dystrophy R9 due to a Novel Complex Insertion/Duplication Variant in <i>FKRP</i> Gene
- Miyoshi Muscular Dystrophy Due to Novel Splice Site Variants in <i>DYSF</i> Gene
- Pathologic Variability Associated With Phenotypic Differences in Siblings With <scp>ACTA1</scp> Myopathy
- Targeted Inhibition in Pediatric MET and ALK-Altered Hemispheric Gliomas: Objective Responses Followed by Treatment Resistance
- ETMR-15. Central Nervous System Embryonal Tumor with EWSR1 translocation: Evolving changes in histology, sequencing, and epigenetics at relapse in 2 patients and potential treatment implications
- A rare presentation of pediatric germinoma mimicking optic pathway glioma: illustrative case
- Navigating molecular neuropathology of CNS neoplasms for the practicing surgical pathologist
- Operative planning for a functional precision medicine assay of recurrent high-grade glioma: illustrative case
- A rare case of atypical intradural extramedullary glioblastoma diagnosed utilizing next-generation sequencing and methylation profiling: illustrative case
- Long-read sequencing for brain tumors
- Functional precision medicine assay for recurrent meningioma: a proof of principle. Illustrative case
- SMARCA4-deficient central nervous system metastases: A case series and systematic review
- Large B-cell Lymphoma With Interferon Regulatory Factor 4 Rearrangement Presenting as a Primary Central Nervous System Lymphoma in the Brain
- Brain Autopsy Findings in a Patient Who Received Lipid Emulsion Therapy for Suspected Drug Intoxication
- Unexpected Presentations of Histiocytic Disorders as Mass Lesions in the Central Nervous System and Spine
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon
- Genomic and Transcriptomic Profiling of Brain Metastases
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon
- Genomic and Transcriptomic Profiling of Brain Metastases
- Spectrum of Hemorrhagic Encephalitis in COVID-19 Patients: A Case Series and Review
- CD8 Encephalitis: A Diagnostic Dilemma
- Spectrum of Acute Necrotizing Hemorrhagic Encephalitis in COVID-19 patients: A case series and Review (P1-1.Virtual)
- Spectrum of Hemorrhagic Encephalitis in COVID-19 Patients: A Case Series and Review
- CD8 Encephalitis: A Diagnostic Dilemma
- Spectrum of Acute Necrotizing Hemorrhagic Encephalitis in COVID-19 patients: A case series and Review (P1-1.Virtual)
- Spectrum of Hemorrhagic Encephalitis in COVID-19 Patients: A Case Series and Review
- CD8 Encephalitis: A Diagnostic Dilemma
- Spectrum of Acute Necrotizing Hemorrhagic Encephalitis in COVID-19 patients: A case series and Review (P1-1.Virtual)
- Spectrum of Hemorrhagic Encephalitis in COVID-19 Patients: A Case Series and Review
- CD8 Encephalitis: A Diagnostic Dilemma
- Spectrum of Acute Necrotizing Hemorrhagic Encephalitis in COVID-19 patients: A case series and Review (P1-1.Virtual)
- Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes
- A novel rotation and scale-invariant deep learning framework leveraging conical transformers for precise differentiation between meningioma and solitary fibrous tumor
- Author Correction: Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes
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