Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-20
Jason S. Stumhofer
Federal Grant PI
High Impact
Associate Professor
Also affiliated: University of Arkansas Medical Center (2013); University of Pennsylvania (2006–2012)
Faculty Researcher
Microbiology & Immunology, College of Medicine
26 h-index
54 pubs
5,400 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Jason S. Stumhofer's research focuses on understanding the immune response during parasitic infections, particularly malaria. He has investigated the roles of different immune cell populations, such as B cells and T cells, in controlling Plasmodium yoelii infection in mice. His work has explored the mechanisms by which B cells develop into memory populations and their ability to respond upon re-challenge, as well as the function of specific proteins like ICOS in germinal center maintenance.
Further research by Dr. Stumhofer examines the regulation of immune cell function during acute infection. This includes investigating the role of cytokines like IL-10 and transcription factors like Bhlhe40 in modulating T cell responses. His federally funded projects, supported by the NIH/National Institute of Allergy and Infectious Diseases, have focused on designing tools to track specific B cells and understanding macrophage function during Plasmodium infection. He has published 52 papers, which have been cited over 5,300 times, contributing to his designation as a highly cited researcher.
Metrics
- h-index: 26
- Publications: 54
- Citations: 5,400
Selected Publications
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Early enhanced control of <i>Plasmodium yoelii</i> infection in IL-10–deficient mice is independent of IFN-γ, IL-12, and the humoral response (2026)
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Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment (2025)
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Bhlhe40 limits early IL-10 production from CD4 <sup>+</sup> T cells during <i>Plasmodium yoelii</i> 17X infection (2023)
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IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i> (2022)
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Towards rainbow portable Cytophone with laser diodes for global disease diagnostics (2022)
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ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection (2022)
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ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection (2021)
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IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i> (2021)
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p53 Controls Murine Gammaherpesvirus Latency and Prevents Infection-Associated <i>IgH/c-Myc</i> Translocations (2020)
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ICOS signaling promotes a secondary humoral response after re-challenge with Plasmodium chabaudi chabaudi AS (2020)
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ICOS expression is not required for memory T cell formation or maintenance, but does promote Tfh cell differentiation and the humoral response after secondary <i>Plasmodium chabaudi chabaudi</i> AS infection (2019)
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The Immunobiology of the Interleukin-12 Family: Room for Discovery (2019)
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Investigating the Role of C/Ebpδ-Deficiency in Radiation-Induced Bone Marrow Failure (2018)
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NK1.1 Expression Defines a Population of CD4+ Effector T Cells Displaying Th1 and Tfh Cell Properties That Support Early Antibody Production During Plasmodium yoelii Infection (2018)
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A subset of NK1.1+ follicular helper CD4+ T cells promotes early extrafollicular plasmablast production during <i>Plasmodium yoelii</i> infection (2017)
Federal Grants 3 $336,449 total
NIH
Contact PI
Jul 2026 - Jun 2028
Development of an organoid model for studying endemic Burkitt lymphoma pathogenesis
NIH
Contact PI
Jun 2024 - Apr 2026
Regulation of macrophage function during acute infection with Plasmodium
NIH
Contact PI
Nov 2021 - Oct 2023
Design of a B cell tetramer to track PfMSP2-specific B cells
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Stumhofer Start up Account UAMS College of Medicine Principal Investigator
- A protective role for IL-17 in blood-stage malaria NIH Principal Investigator
- Multicolor Photoacoustic Malaria Detector NIH Co-Investigator
- Understanding the contribution of atypical B cell progenitors to the humoral response NIH Principal Investigator
- Regulation and function of B cells during malaria infection- Resubmission NIH Principal Investigator
- Defining mechanisms of gammaherpesvirus-driven genomic instability in B cells NIH Co-Investigator
Collaboration Network
Top Collaborators
Enatha Ntirandekura
University of Arkansas for Medical Sciences
4 shared publications
In database
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i>
- ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection
- IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i>
- ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection
Kara A. O’Neal
University of Arkansas for Medical Sciences
3 shared publications
In database
- Bhlhe40 limits early IL-10 production from CD4 <sup>+</sup> T cells during <i>Plasmodium yoelii</i> 17X infection
- ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection
- ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection
Camille L. Foscue
University of Arkansas for Medical Sciences
3 shared publications
In database
- Bhlhe40 limits early IL-10 production from CD4 <sup>+</sup> T cells during <i>Plasmodium yoelii</i> 17X infection
- ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection
- ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection
Susie L. Brown
University of Arkansas for Medical Sciences
2 shared publications
In database
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i>
- IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i>
Jonathan J. Bauer
University of Arkansas for Medical Sciences
2 shared publications
In database
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i>
- IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i>
Juhyung Lee
University of Arkansas for Medical Sciences
2 shared publications
In database
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i>
- IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i>
Leah E. Latham
University of Arkansas for Medical Sciences
2 shared publications
In database
- ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection
- ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to <i>P. yoelii</i> infection
Hind J. Jawad
University of Arkansas for Medical Sciences (US)
1 shared publication
- Towards rainbow portable Cytophone with laser diodes for global disease diagnostics
Aayire C. Yadem
University of Arkansas for Medical Sciences (US)
1 shared publication
- Towards rainbow portable Cytophone with laser diodes for global disease diagnostics
Yulian A. Menyaev
University of Arkansas for Medical Sciences
1 shared publication
In database
- Towards rainbow portable Cytophone with laser diodes for global disease diagnostics
Mustafa Sarimollaoglu
University of Arkansas for Medical Sciences
1 shared publication
In database
- Towards rainbow portable Cytophone with laser diodes for global disease diagnostics
Jillian N. Armstrong
Yale University (US)
1 shared publication
- Towards rainbow portable Cytophone with laser diodes for global disease diagnostics
Fumiya Watanabe
University of Arkansas at Little Rock
1 shared publication
In database
- Towards rainbow portable Cytophone with laser diodes for global disease diagnostics
Alexandru S. Biris
University of Arkansas at Little Rock
1 shared publication
In database
- Towards rainbow portable Cytophone with laser diodes for global disease diagnostics
Dmitry A. Nedosekin
University of Arkansas for Medical Sciences
1 shared publication
In database
- Towards rainbow portable Cytophone with laser diodes for global disease diagnostics
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