Biography and Research Information
OverviewAI-generated summary
Sharda P. Singh's research investigates the role of oxidative stress and mitochondrial dysfunction in neurodegenerative diseases, particularly Alzheimer's disease. Her work has explored the function of RALBP1 (RLIP76) in these processes, utilizing autopsy brains from Alzheimer's patients and immortalized hippocampal neurons. Singh also examines the impact of oxidative stress on other conditions, including skin aging and breast cancer, and has investigated potential therapeutic interventions such as dietary supplementation with sulforaphane and iron chelation.
Her publications include studies on the Keap1-Nrf2 pathway in skin aging and the anticancer activity of omega-6 fatty acids. Singh's recent work also addresses age-related skeletal muscle sarcopenia in mice, employing iron chelation as a preventative measure. With an h-index of 25 and over 2,500 citations from more than 110 publications, she is recognized as a highly cited researcher. Singh collaborates with several researchers at the University of Arkansas for Medical Sciences, including Chhanda Bose, Philip Palade, Elisabet Børsheim, and Ashley Nemec-Bakk.
Metrics
- h-index: 25
- Publications: 110
- Citations: 2,600
Selected Publications
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Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging (2025)
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Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway (2021)
Collaboration Network
Top Collaborators
- Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
- Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
- Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
- Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
- Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
- Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
- Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
- Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
- Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
- Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
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