Philip Palade

High Impact

Professor

UAMS

Last publication 2025 Last refreshed 2026-05-02

faculty

Pharmacology & Toxicology, College of Medicine

39 h-index 128 pubs 5,110 cited

Research Areas

Links

ORCID Lab Website Research Group UAMS TRI Profile

OverviewAI-generated summary

Philip Palade, Professor in the Department of Pharmacology & Toxicology at the University of Arkansas for Medical Sciences, investigates molecular mechanisms underlying diseases, with a recent focus on cardiovascular diseases and neurodegenerative conditions. His work has explored the role of proteins such as RALBP1 in oxidative stress and mitochondrial dysfunction, particularly in the context of Alzheimer's disease and mammary carcinogenesis. He has also studied the impact of PCSK9 on smooth muscle cell senescence and apoptosis, and its broader implications in cardiovascular health beyond cholesterol metabolism. Further research interests include the immune pathways involved in hypertension and the anticancer activities of specific dietary components, such as omega-6 fatty acids and sulforaphane.

Dr. Palade's scholarship includes 128 publications and over 5,100 citations, reflected in an h-index of 39. He is recognized as a highly cited researcher. His collaborations within the University of Arkansas for Medical Sciences include significant work with Sharda P. Singh (6 shared publications), Chhanda Bose (5 shared publications), Yunmeng Liu (2 shared publications), and Katherine Deck (2 shared publications). Dr. Palade maintains an active research group and laboratory website, indicating ongoing research activities.

Metrics

h-index: 39
Publications: 128
Citations: 5,110

Selected Publications

Uncovering immune pathways for therapeutic targeting of hypertension (2025)

DOI OpenAlex
Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications (2025)

DOI OpenAlex
The pleiotropic effects of PCSK9 in cardiovascular diseases beyond cholesterol metabolism (2025)

3 citations DOI OpenAlex
Direct Impact of PCSK9 on SMC Senescence and Apoptosis: A New Focus in Cardiovascular Diseases (2024)

5 citations DOI OpenAlex
Book Review of Heart Disease: It is All in Your Head, and What to Do About It (2022)

DOI OpenAlex
Rlip Depletion Alters Oncogene Transcription at Multiple Distinct Regulatory Levels (2022)

DOI OpenAlex
Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells (2021)

14 citations DOI OpenAlex
RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease (2021)

22 citations DOI OpenAlex
Role of RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease (2021)

7 citations DOI OpenAlex
Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway (2021)

21 citations DOI OpenAlex
Haploinsufficiency Interactions between RALBP1 and p53 in ERBB2 and PyVT Models of Mouse Mammary Carcinogenesis (2021)

7 citations DOI OpenAlex

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Grants & Funding

CALCIUM RELEASE FROM ISOLATED SARCOPLASMIC RETICULUM NIH Principal Investigator
Cav1.2 Transcript Regulation in Heart and Smooth Muscle NIH Principal Investigator
RNA interference to decrease vascular CaV1.2 in hypertension American Heart Association (South Central Affiliate) Principal Investigator
THE ALPHA-1C CALCIUM CHANNEL IN MUSCLE NIH Principal Investigator
CA RELEASE FROM SARCOPLASMIC RETICULUM: THE FROG PACKAGE NIH Principal Investigator
PHARMACOLOGY OF MUSCLE EXCITATION-CONTRACTION COUPLING NIH Principal Investigator
CALCIUM RELEASE PROCESS OF SARCOPLASMIC RETICULUM NIH Principal Investigator
CALCIUM RELEASE PROCESS OF SARCOPLASMIC RETICULUM NIH Principal Investigator