Match tier
Listed
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
P
Philip Palade
High Impact
Professor
Also affiliated: Muscular Dystrophy Association (1983); University of Padua (1994); Haverford College (1968); University of Cologne (1994); Anhui Medical University (2013); Vanderbilt University (1983–1984); University of Washington (1977–1985); San Diego State University (1994–2001); University of Arkansas Medical Center (2008–2009); Central Arkansas Veterans Healthcare System (2013); First Affiliated Hospital of Anhui Medical University (2013); The University of Texas Medical Branch at Galveston (1983–2006); Southern Medical University (2013); Rice University (2010); University of Pennsylvania (1977); Saarland University (1980–1981)
Pharmacology & Toxicology, College of Medicine
39 h-index
128 pubs
5,152 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Philip Palade's research focuses on the physiological mechanisms of ion channel function in muscle and cardiac tissue. His work has investigated calcium and chloride conductances in various muscle preparations, including frog muscle membrane and rat diaphragm fibers. He has explored the effects of external ions, such as calcium, on these conductances, as well as the influence of substances like local anesthetics on sodium channel function.
Palade has also contributed to understanding slow calcium and potassium currents across muscle membranes using specialized techniques. His more recent publications have touched upon vascular calcium channels, their role in high blood pressure, and therapeutic implications. His scholarly output includes 128 publications with over 5,151 citations, and he holds an h-index of 39, reflecting his recognition as a highly cited researcher. He leads a research group and collaborates with colleagues at the University of Arkansas for Medical Sciences, including Sharda P. Singh and Chhanda Bose.
Metrics
- h-index: 39
- Publications: 128
- Citations: 5,152
Positions
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Professor publications 2006–2025University of Arkansas for Medical Sciences Pharmacology & Toxicology, College of Medicine Institutional directory
Selected Publications
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Uncovering immune pathways for therapeutic targeting of hypertension (2025)
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Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications (2025)
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The pleiotropic effects of PCSK9 in cardiovascular diseases beyond cholesterol metabolism (2025)
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Direct Impact of PCSK9 on SMC Senescence and Apoptosis: A New Focus in Cardiovascular Diseases (2024)
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Book Review of Heart Disease: It is All in Your Head, and What to Do About It (2022)
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Rlip Depletion Alters Oncogene Transcription at Multiple Distinct Regulatory Levels (2022)
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Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells (2021)
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RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease (2021)
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Role of RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease (2021)
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Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway (2021)
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Haploinsufficiency Interactions between RALBP1 and p53 in ERBB2 and PyVT Models of Mouse Mammary Carcinogenesis (2021)
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Multi-omic analysis reveals the anti-aging impact of sulforaphane on the microbiome and metabolome (2020)
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KATP Channel Openers Inhibit Lymphatic Contractions and Lymph Flow as a Possible Mechanism of Peripheral Edema (2020)
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Sulforaphane prevents age‐associated cardiac and muscular dysfunction through Nrf2 signaling (2020)
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Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice (2020)
Grants & Funding
As listed on this researcher's institutional profile.
- CALCIUM RELEASE FROM ISOLATED SARCOPLASMIC RETICULUM NIH Principal Investigator
- Cav1.2 Transcript Regulation in Heart and Smooth Muscle NIH Principal Investigator
- RNA interference to decrease vascular CaV1.2 in hypertension American Heart Association (South Central Affiliate) Principal Investigator
- THE ALPHA-1C CALCIUM CHANNEL IN MUSCLE NIH Principal Investigator
- CA RELEASE FROM SARCOPLASMIC RETICULUM: THE FROG PACKAGE NIH Principal Investigator
- PHARMACOLOGY OF MUSCLE EXCITATION-CONTRACTION COUPLING NIH Principal Investigator
- CALCIUM RELEASE PROCESS OF SARCOPLASMIC RETICULUM NIH Principal Investigator
- MicroRNA to decrease vascular CaV1.2 in hypertension NIH Principal Investigator
- PHARMACOLOGY OF QUANTAL INTRACELLULAR CALCIUM RELEASE NIH Principal Investigator
- CA INDUCED CA RELEASE FROM STRIATED MUSCLE NIH Principal Investigator
Collaboration Network
Top Collaborators
Sharda P. Singh
Texas Tech University
12 shared publications
In database
- Sulforaphane prevents age‐associated cardiac and muscular dysfunction through Nrf2 signaling
- Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice
- Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
- RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Topical 2′-Hydroxyflavanone for Cutaneous Melanoma
Showing 5 of 12 shared publications
Sanjay Awasthi
Texas Tech University (US)
12 shared publications
- Sulforaphane prevents age‐associated cardiac and muscular dysfunction through Nrf2 signaling
- Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice
- Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
- RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Topical 2′-Hydroxyflavanone for Cutaneous Melanoma
Showing 5 of 12 shared publications
Chhanda Bose
Texas Tech University
10 shared publications
In database
- Sulforaphane prevents age‐associated cardiac and muscular dysfunction through Nrf2 signaling
- Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice
- RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Topical 2′-Hydroxyflavanone for Cutaneous Melanoma
- Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells
Showing 5 of 10 shared publications
Ashly Hindle
Texas Tech University (US)
6 shared publications
- RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Topical 2′-Hydroxyflavanone for Cutaneous Melanoma
- Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells
- Rlip Depletion Suppresses Growth of Breast Cancer
- Haploinsufficiency Interactions between RALBP1 and p53 in ERBB2 and PyVT Models of Mouse Mammary Carcinogenesis
Showing 5 of 6 shared publications
Abhilash Krishna
Rice University (US)
4 shared publications
- Rate-dependent Ca2+ signalling underlying the force-frequency response in rat ventricular myocytes: a coupled electromechanical modeling study
- Modeling CICR in rat ventricular myocytes: voltage clamp studies
- Multiphysics model of a rat ventricular myocyte: A voltage-clamp study
- Ca2+ Signaling in Rat Ventricular Myocytes
Miguel Valderrábano
Houston Methodist (US)
4 shared publications
- Rate-dependent Ca2+ signalling underlying the force-frequency response in rat ventricular myocytes: a coupled electromechanical modeling study
- Modeling CICR in rat ventricular myocytes: voltage clamp studies
- Multiphysics model of a rat ventricular myocyte: A voltage-clamp study
- Ca2+ Signaling in Rat Ventricular Myocytes
Sharad S. Singhal
City of Hope (US)
4 shared publications
- Topical 2′-Hydroxyflavanone for Cutaneous Melanoma
- Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells
- Rlip Depletion Suppresses Growth of Breast Cancer
- Haploinsufficiency Interactions between RALBP1 and p53 in ERBB2 and PyVT Models of Mouse Mammary Carcinogenesis
Ji‐Hyun Lee
Texas Tech University (US)
4 shared publications
- Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells
- Rlip Depletion Suppresses Growth of Breast Cancer
- Haploinsufficiency Interactions between RALBP1 and p53 in ERBB2 and PyVT Models of Mouse Mammary Carcinogenesis
- Rlip Depletion Alters Oncogene Transcription at Multiple Distinct Regulatory Levels
Li Pang
University of Arkansas for Medical Sciences
3 shared publications
In database
- Vascular-Specific Increase in Exon 1b-Encoded CaV1.2 Channels in Spontaneously Hypertensive Rats
- Angiotensin II causes endothelial-dependent increase in expression of CaV1.2 protein in cultured arteries
- Angiotensin II Upregulates CaV1.2 Protein Expression in Cultured Arteries via Endothelial H2O2 Production
John W. Clark
Rice University (US)
3 shared publications
- Rate-dependent Ca2+ signalling underlying the force-frequency response in rat ventricular myocytes: a coupled electromechanical modeling study
- Modeling CICR in rat ventricular myocytes: voltage clamp studies
- Ca2+ Signaling in Rat Ventricular Myocytes
Xianwei Wang
First Affiliated Hospital of Xinxiang Medical University (CN)
3 shared publications
- High Fat Diet Causes Renal Fibrosis in LDLr-null Mice Through MAPK-NF-κB Pathway Mediated by Ox-LDL
- Direct Impact of PCSK9 on SMC Senescence and Apoptosis: A New Focus in Cardiovascular Diseases
- The pleiotropic effects of PCSK9 in cardiovascular diseases beyond cholesterol metabolism
Se‐Ran Jun
University of Arkansas for Medical Sciences
3 shared publications
In database
- Sulforaphane prevents age‐associated cardiac and muscular dysfunction through Nrf2 signaling
- Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice
- Multi-omic analysis reveals the anti-aging impact of sulforaphane on the microbiome and metabolome
Amrita K. Cheema
University of Washington (US)
3 shared publications
- Sulforaphane prevents age‐associated cardiac and muscular dysfunction through Nrf2 signaling
- Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice
- Multi-omic analysis reveals the anti-aging impact of sulforaphane on the microbiome and metabolome
Marjan Boerma
University of Arkansas for Medical Sciences
3 shared publications
In database
- Sulforaphane prevents age‐associated cardiac and muscular dysfunction through Nrf2 signaling
- Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice
- Multi-omic analysis reveals the anti-aging impact of sulforaphane on the microbiome and metabolome
Eugénia Carvalho
University of Coimbra (PT)
3 shared publications
- Sulforaphane prevents age‐associated cardiac and muscular dysfunction through Nrf2 signaling
- Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice
- Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
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