Intawat Nookaew Institution Verified

Sourced from institutional research profiles (UAMS TRI or ARA).

High Impact

Professor

University of Arkansas for Medical Sciences

faculty

Biomedical Informatics, College of Medicine

inookaew@uams.edu

57 h-index 306 pubs 17,703 cited

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Biography and Research Information

OverviewAI-generated summary

Intawat Nookaew's research focuses on applying computational and analytical methods to understand biological systems, particularly in the areas of genomics, transcriptomics, and metabolomics. His work has contributed to the genetic understanding of various organisms, including the black tiger shrimp (*Penaeus monodon*), where his group facilitated a chromosome-level genome assembly to identify growth-associated genes. Nookaew also investigates extrachromosomal circular DNA (eccDNA), developing computational tools like CReSIL for its accurate identification from long-read sequencing data. His research extends to human health, exploring the roles of circular DNA in the human germline and its association with recombination, as well as examining metabolic profiles in autism spectrum disorders. Further studies include investigating the molecular mechanisms behind bone loss and resorption, particularly in the context of osteoporosis and the effects of treatments like denosumab discontinuation and oxidized phospholipids.

With a substantial publication record of over 300 articles and a high citation count, Nookaew is recognized as a highly cited researcher. He leads an active research group at the University of Arkansas for Medical Sciences and collaborates with several colleagues within the institution, including Thidathip Wongsurawat and Piroon Jenjaroenpun, with whom he has co-authored numerous publications. His scholarly metrics, including an h-index of 57, indicate a significant impact in his fields of study. Nookaew's recent work continues to explore these diverse areas, with publications dating up to 2023 and indications of ongoing research activity.

Metrics

  • h-index: 57
  • Publications: 306
  • Citations: 17,703

Selected Publications

  • Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength (2025) DOI
  • Oat bran fiber protects against radiation-induced disruption of gut barrier dynamics and mucosal damage (2025) DOI
  • Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment (2025) DOI
  • Investigating the origins of the mutational signatures in cancer (2025) DOI
  • CAIM: coverage-based analysis for identification of microbiome (2024) DOI
  • Sensitivity and specificity of Nanopore sequencing for detecting carbapenem and 3rd-generation cephalosporin-resistant Enterobacteriaceae in urine samples: Real-time simulation with public antimicrobial resistance gene database (2024) DOI
  • Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis (2024) DOI
  • Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone (2024) DOI
  • Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome (2024) DOI
  • A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma (2024) DOI
  • High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma (2023) DOI
  • Long-term benefit of DAAs on gut dysbiosis and microbial translocation in HCV-infected patients with and without HIV coinfection (2023) DOI
  • Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation (2023) DOI
  • Exploiting nanopore sequencing for characterization and grading of <i>IDH</i>‐mutant gliomas (2023) DOI
  • CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system (2023) DOI

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